The relationship between physical activity and thyroid hormones in pregnant women
Subject Areas : Effects of Movement and Exercise in HealthKurosh Razi 1 , سید علی حسینی 2 , abas Moghadasi 3
1 - Department of Physical Education, Shiraz Branch, Islamic Azad University, Shiraz, Iran
2 - گروه مدیریت ورزش، واحد مرودشت، دانشگاه آزاد اسلامی، مرودشت، ایران.
3 - Department of Exercise physiology, Shiraz branch, Islamic Azad University, Shiraz, Iran
Keywords: Physical Activity, Thyroid Hormones, Pregnancy,
Abstract :
Background and Purpose: Pregnancy is associated with many anatomical and physiological changes, and a healthy pregnancy requires metabolic and hormonal adaptation that involves the hypothalamus, pituitary, parathyroid and adrenal glands. Studies have shown that proper nutrition along with physical activity can have positive effects on hormonal responses. The aim of this study was to investigate the relationship between physical activity and thyroid hormones in pregnant women. Material and Methods: In this causal-comparative study, 60 pregnant mothers (average weight 64.92±8.59 kg and height 161.88±7.30 cm) referred to Dr. Baziari's laboratory in Shiraz (for self and fetal health screening) were selected as a statistical sample. To measure thyroid hormones, 5 cc of blood samples were taken from the vein of the anterior part of the elbow, and to measure physical activity, the PPAQ standard questionnaire for pregnant women was used. Kolmogorov- Smirnov statistical and Pearson's correlation coefficient tests were used to analyze the research findings (P≥0.05). Results: The results showed that there is no significant relationship between home activity (P=0.90), transportation activity (P=0.59), work environment activity (P=0.34), sports and entertainment activities (29 (P=0.0) and total physical activity (P=0.25) TSH. Also, there is no significant relationship between home activity (P=0.94), transportation activity (P=0.56), work environment activity (P=0.14), sports and entertainment activities (P=0.78) and total physical activity (P=0.51) with T4 and finally there is no significant relationship between home activity (P=0.11), transport activity (P=0.20), work environment activity (P=0.44), sports and entertainment activities (P=0.41) and total physical activity (P=0.82) with T3.
1. Stagnaro-Green A, Abalovich M, Alexander E, Azizi F, Mestman J, Negro R, et al. Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and Postpartum. Thyroid 2011;21(10):1081-1125
2. Yamamoto T, Amino N, Tanizawa O, Ichihara K, Azukizawa M, Miyai K. Longitudinal study of serum thyroid hormones, chorionic gonadotrophin and thyrotrophin during and after normal pregnancy. Clin Endocrinol 1979;10(5):459-68.
3. Casey BM, Leveno KJ. Thyroid disease in pregnancy. Obstet Gynecol. 2006; 108(5):1283–92.
4. Kahn M, Robien K, DiPietro L. Maternal leisure-time physical activity and risk of preterm birth: a systematic review of the literature. J Physical Act Health 2016;13(7):796–807.
5. Johnson M, Campbell F, Messina J, Preston L, Buckley Woods H, Goyder E. Weight management during pregnancy: a systematic review of qualitative evidence. Midwifery 2013;29(12):1287–96.
6. Barakat R, Perales M, Garatachea N, Ruiz J, Lucia A.Exercise during pregnancy. A narrative review asking: what do we know? Br J Sports Med 2015;49(21): 1377–81.
7. Mokaberian M, Farokhi A, Tahmasebi Boroujeni S.The effect of exercise during pregnancy on health indexes of infants. Motor Behavior 2015; 18(6): 71-84. [Farsi]
8. Currie L, Woolcott Ch, Fell D, Armson A, Dodds L.The Association between Physical Activity and Maternal and Neonatal Outcomes: A Prospective Cohort. Matern Child Health J 2014; 18(8): 1823–30.
9. Monk C, Fifer WP, Myers MM, Sloan RP, Trien L, Hurtado A. . .Maternal stress responses and anxiety during pregnancy: Effects on fetal heart rate. Dev Psychobiol 2000; 36(1): 67-77.
10. Yoo S, Zeanah M. ACOG guidelines on exercise during pregnancy: effect on pregnancy outcome. J Obstet Gynecol Neonatal Nurs 2008 Apr;26(4):265-9.
11. Clapp 3rd JF. Long-termoutcome after exercising throughout pregnancy: fitness and cardiovascular risk. Am J Obstet Gynecol 2008;199(5):489 [e1–6].
12. Clapp J. Child and maternal health with exercise: a clinical update. Clin Sport Med J 2008,5:20-33.
13. Abbasi, S., Moazami, M., Bijeh, N., & Mirmajidi, S. R. (2015). Investigation of the Relationship between Physical Activity Levels, Maternal Weight (before delivery) and Serum Cortisol Level (during labor) in Nulliparous Women. The Iranian Journal of Obstetrics, Gynecology and Infertility, 18(151), 12-19. doi: 10.22038/ijogi.2015.4625
14. Chasan-Taber L, Schmidt MD, Roberts DE, Hosmer D, Markenson G, Freedson PS. Development and validation of pregnancy physical activity questionnaire. Med Sci Sports Exerc 2004; 36(10): 1750-60.
15. Mehran N, Abbaszadeh F, Bagheri A, Noroozi M. Relation between Home Work and Preterm Labor. hayat 2012; 18(5): 46-54.
16. Kazemi A, Ahmadi P. Relationship between physical activity during the first 20 weeks of gestation and hypertension in pregnancy. J Shahrekord Univ Med Sci. 2007; 9 (2) :20-27.
17. Manar LK, Escott SV. Food nutrition & diet theraphy. 11th ed. Philadelphia: RA Chelk-Johnson;2004. p: 21.
18. Borhani Haghighi M, Pasand Mojdeh H, Alipour F. The Role of Thyroid Hormones in the Central Nervous System. Shefaye Khatam 2017; 5 (4) :87-97.
19. Delshad H, and Azizi F. Thyroid and pregnancy. Journal of medical council of iran. 2008 (26): 392- 408.
20. Menna Allah Mohammed Abbas, Salwa Mostafa El Badrey, Abeer Mohamed ElDeeb, Ahmed Mahmoud Sayed. Effect of aerobic exercises on the thyroid hormones in treated hypothyroid pregnant women. J Adv Pharm Edu Res 2019;9(4):49-53.
21. alimoradi S, valipour dehnou V, fathi M. The Effect of a Period of Aerobic Training on Serum Levels of IGF-1 and Thyroid Hormones in Women with Subclinical Hypothyroidism. cmja 2019; 9 (1) :3583-3597
22. Nikseresht, A., Jahromi, M., Basirat, N., & Sobhanian, S. (2022). Influence of aerobic exercise and Ramadan fasting on fluctuation of some blood hormones. Pars Journal of Medical Sciences, 7(4), 23-34. doi: 10.29252/jmj.7.4.4
23. sobhani, V., & shirvani, H. (2022). The Effect of a Period of Selected Aerobic Training on the Response of Thyroid and Cortisol Hormones to Exhaustive Exercise in Women. Journal of Military Medicine, 18(3), 253-261.
24. Boyden TW, Pamenter RW, Stanforth P, Rotkis T, Wilmore JH. Evidence for Mild Thyroidal Impairment in Women Undergoing Endurance Training. The Journal of Clinical Endocrinology & Metabolism. 1982 Jan; 54(1):53-6.
25. Pourvaghar MJ, Shahsavar A. The alteration of serum thyroid hormone and its stimulating in nanoscale on athletics men. Digest Journal of Nanomaterials and Biostructures. 2009 Jun 1; 4(2):263-7
26. Sheffield JS, Cunningham FG. Thyrotoxicosis and heart failure that complicate pregnancy. American journal of obstetrics and gynecology. 2004;190(1):211-7
27. Papendieck P, Chiesa A, Prieto L, Gruneiro-Papendieck L. Thyroid disorders of neonates born to mothers with Graves' disease. Journal of pediatric endocrinology & metabolism : JPEM. 2009;22(6):547-53.
28. Mandel SJ, Cooper DS. The use of antithyroid drugs in pregnancy and lactation. The Journal of clinical endocrinology and metabolism. 2001;86(6):2354-9.
29. Anckaert E, Poppe K, Van Uytfanghe K, Schiettecatte J, Foulon W, Thienpont LM. FT4 immunoassays may display a pattern during pregnancy similar to the equilibrium dialysis ID-LC/tandem MS candidate reference measurement procedure in spite of susceptibility towards binding protein alterations. Clin Chim Acta. 2010;411(17-18):1348-53
30. Pakarinen A, Alén M, Häkkinen K, Komi P. Serum thyroid hormones, thyrotropin and thyroxine binding globulin during prolonged strength training. Eur J Appl Physiol Occup Physiol. 1988;57:394-8.
31. Darya Noosh F, Saeb M, Sheykhani, H. The study on the effects of twelve-weeks aerobic Exercise on the changes in some antioxidants and thyroid hormones and the relationship between them in non-athlete female university students. J Manag Sys. 2011;6:1-12.
32. Baghian, T., Heidarian Pour, A., & Shokri, E. (2018). The Effects of Submaximal Endurance Training/Detraining and Gonadotropin Releasing Hormone Agonists on Growth and Thyroid Hormones Serum Concentrations in Girls with Precocious Puberty. Sport Physiology, 10(40), 51-68. doi: 10.22089/spj.2019.5830.1765
