The role of adrenergic system on the effect of EMF on acute pain sensation
Subject Areas : clinical veterinary scienceM.R Rahimnejad, 1 , M.R. Zarindast 2
1 - Department of Basic Science, Faculty of Veterinary Medicine
2 - Islamic Azad University, Karaj Branch, Iran
Keywords: pain, α Adrenergic, β Adrenergic, EMF,
Abstract :
Although numerous factors participate in pain sensation, efficient studies have never been performed on these factors yet. Among these factors modifying effects of Electro Magnetic Field (EMF) on both intensity and durationof pain sensation is undeniable.This study has been performed on ten quintet groups of mice. In fact, the role of adrenergic system on the effect ofEMF on acute pain sensation has been examined treating with four drugs (yohimbine, xylazine, propranolol andsalbutamol). The animals were divided into two groups, the first group were exposed to EMF (one hour in a dayfor 7 days), whereas the second group did not. Both groups were treated with the drugs (IP) separately.The results revealed that Yohimbin (α2 Blocker) decreased and Xylazine (α2 Agonist) increased the analgesiceffect of EMF on acute pain but Propranolol (β1, β2, β3 Blocker) and Salbutamol (β2 Agonist) didn’t show anysignificant difference in analgesic effect of EMF on acute pain.In conclusion, the results showed that the EMF has the antinociceptive effect on the acute pain threshold via adrenergic system.
