Evaluation of allergic rhinitis frequency in patient with migraine without aura who refers to 22 bahman neurology clinic during 2013-2014

Subject Areas : علوم پزشکی

Alireza Al Hashem ¹ , Maryam Hassan Pour Moghadam ² , Mahbubeh Adami Dehkordi ³

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Received: 2017-06-06 Accepted : 2017-06-06 Published : 2013-05-22

Keywords: IgE, Migraine without Aura, allergic rhinitis,

Abstract :

Background: In the recent years, base on the reports of allergists and otolaryngologists, the correlation between allergic diseases and migraine headaches has increased. This is partially due to a better understanding of inflammatory mediators with vasoactive function that play an important role in these diseases. This study aimed to evaluation of allergic rhinitis frequency in patients with migraine without aura. Methods: This analytical-descriptive study was carried out on 212 patients with migraine without aura who refers to neurology clinic of a university hospital in Mashhad, Iran. The diagnosis of migraine without aura was assessed according to IHS (International Headache Society) criteria. All of these patients evaluated for allergic rhinitis. The tool of gathering the data was a questionnaire asking about age, sex, marital status, family history and clinical symptoms of allergic rhinitis; also total serum IgE levels were estimated in patients with clinical symptoms of allergic rhinitis by using enzyme linked immunosorbent assay (ELISA) kit. Data was analyzed by SPSS and P < 0.005 considered as the level of significance.  Findings: A total of 212 patients (59% female and 48% male, mean age 30.9 years) participated in the study. The frequency of allergic rhinitis in migraine patients was 28.3%. There was a significant difference between frequency of allergic rhinitis and frequency of migraine attacks (P < 0.0001), but there wasn’t significant difference between frequency of allergic rhinitis with age, sex, marital status, family history and clinical symptoms of allergic rhinitis. Conclusion: We propose that inflammatory mediators play a key role in triggering migraine by means of vasodilation and inflammation in the pathogenesis of migraine headaches. Thus, the avoidance of conditions that cause allergic reactions in migraine patients may be a simple and effective way for prophylaxis or their treatment.  

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