بررسی فراوانی اختلالات عملکرد تیروئید در بیماران دیابت تیپ 2 مراجعه کننده به کلینیک داخلی بیمارستان 22 بهمن مشهد، بین سالهای 1392 تا 1393

Subject Areas : علوم پزشکی

Sahar  Ghare ¹ (متخصص غدد، استادیار دانشکده پزشکی دانشگاه آزاد اسلامی واحد مشهد)
Golnaz  Latifian ² (دانشجوی پزشکی دانشگاه آزاد اسلامی واحد مشهد)
Vahid  Pooresmaeel ³ (نویسنده پاسخگو، PhD ، استادیار گروه بیوشیمی دانشکده پزشکی دانشگاه آزاد اسلامی واحد مشهد)

Received: 2017-02-22 Accepted : 2017-02-22 Published : 2016-09-22

Keywords: frequency, Diabetes mellitus, Thyroid dysfunction,

Abstract :

Background: Thyroid diseases are common in public population. New methods of evaluation have made it efficient and cheap to detect these diseases in special groups. According to previous studies the prevalence of thyroid dysfunction is higher in diabetic patients compare to normal population. Moreover, poor control of metabolism is associated with increased rate of thyroid dysfunction. In this study we decided to evaluate the frequency of thyroid dysfunction in type 2 diabetic patients.   Methods: This is a cross sectional study in which patients visited the internal medicine clinic at 22 Bahman hospital in Mashhad from 2013 till 2014 were evaluated. 524 type 2 diabetic adult patients (over 18 years old) were included (184 males and 340 females). Exclusion criteria were pregnancy, acute and severe disease during the last 3 months, using any of the following medicines: glucocorticoids, amiodarone, interferon, iodide and lithium. TSH, FT4, Age, gender and existence of goiter were compared among all the patients. Results: From all 524 type 2 diabetic patients with the mean age of 56 years, 28.2% suffered from thyroid dysfunction. 20.2% had clinical hypothyroidism, 3.8% had subclinical hypothyroidism, 1.9% had clinical hyperthyroidism, 1.3% had subclinical hyperthyroidism and 1% had goiter. There was a statistically meaningful association between age and clinical hyperthyroidism (p=0.012), that shows the frequency was higher in younger than 50 years and also between subclinical hypothyroidism and existence of goiter (p= 0.013). Conclusion: The Frequency of thyroid dysfunction in type 2 diabetic patients is clearly higher than overall prevalence reported in the country (10.5%). According to this significant differences and also effects of thyroid function in glucose and lipid metabolism, so it seems logical to evaluate thyroid function in diabetic patients.

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