The Effectiveness of Mindfulness-based Cognitive Therapy on Depression, Auality of Life, and Serum Cortisol Levels of Depressed People

Subject Areas : Journal of Animal Biology

Zahra  Olyaie ¹ (Department of Clinical Psychology, Shiraz Branch, Islamic Azad University, Shiraz, Iran.)
Masoud  Mohammadi ² (Department of Clinical Psychology, Shiraz Branch, Islamic Azad University, Shiraz, Iran.)
Kazem  Anvari ³ (Cancer Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.)
SeyedEbrahim  Hosseini ⁴ (Department of Physiology, Shiraz Branch, Faculty of Science, Zand Shiraz Institute of Higher Education, Shiraz, Iran.)

Received: 2021-11-07 Accepted : 2022-01-10 Published : 2022-08-23

Keywords: Cortisol, mindfulness-based cognitive therapy, Quality of Life (QoL), Depressed People,

Abstract :

Depression is now a common chronic illness in most communities all over the world that may disrupt normal functioning, cause depressive thoughts, and negatively affect the quality of life (QoL). The aim of this study was to assess the effectiveness of mindfulness-based cognitive therapy on quality of life (QoL), depression and cortisol levels in people with depression. Thirty women with depression were selected voluntarily and randomly assigned to experimental (n = 15) and control (n = 15) groups. For the experimental group, treatment sessions were held for eight 90-minute sessions per week and the control group did not receive any treatment. To measure the variables, Beck Depression Inventory (BDI-II and SF36 Quality of Life Questionnaire) was used twice (before and after treatment) and to measure cortisol levels, blood samples were taken between 8 and 10 am before the onset of first and last treatment sessions and analysis of covariance (ANCOVA) was employed to analyze the data. The results showed that mindfulness-based cognitive therapy in the pretest-posttest phase reduced depression and cortisol rate from 23.87 and 14.48 to 10.13 and 11.95, respectively and increased quality of life from 32.90 to 83.52 in the experimental group (p < 0.001). Based on the findings of the present study, it can be concluded that mindfulness-based cognitive therapy can improve the mental status and quality of life of patients with depression.

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