The effect of intraperitoneal injection of alcoholic extract Foeniculum vulgare seed on gonadotropic and testosterone hormones in male wistar rats

Subject Areas : Journal of Animal Biology

سیده فهیمه  میرسید ¹ (کارشناسی ارشد بیولوژی جانوری دانشگاه آزاد اسلامی واحد دامغان)
عبدالحسین  شیروی ² (استادیار دانشگاه آزاد اسلامی واحد دامغان)
میترا  حیدری نصرآبادی ³ (استادیاردانشگاه آزاد اسلامی واحد پرند)

Received: 2014-06-24 Accepted : 2017-05-21 Published : 2008-11-21

Keywords: Testosterone, Testis, FSH, LH, Rat, Alcoholic extract Feenel,

Abstract :

Always population increase is assumed one the main problems of societies and population control with chemical drugs is one of the most human concern.Side effects of use this drugs drives human to use of vegetable drugs. Foeniculum vulgare is one of them witch this current study addressed to survey the effect of its seed alcoholic extract on gonadotropin hormones changes. In this study is used the male rat of wistar race 2-3 month aged (with the approximated weight of 190andplusmn;10 gr). Animal was classified to four experimental group and one control groups. Four experimental group for 15 days was received the doses of 35,70,140,280 mg/kg of fennel seed alcoholic extract. At this time was inject the physiology serum to control group intraperitonealy(IP). During experimental take place blood sampling from animals in 7 and 15 to asses the hormone and the testosterone hormone such as LH, FSH was evaluated with considering to results the level of LH, FSH in case group in first week has significant difference to control group at sometime and decreasing trend in dose of 35 to 280 mg/kg. Furthermore the levels of these hormones in second week at case groups show the significant difference with decreasing trend. This is Warthy to say that the level of testosterone hormone has significant difference only between first and second week.