The Effects of Inhaling the Toxic Mixture of Bleach and Detergent Materials on Leukocytes of Mice

Subject Areas : Journal of Animal Biology

غلامحسن  واعظی ¹ (دانشیار دانشگاه آزاد اسلامی واحد سمنان، سمنان، ایران)
فاطمه  طوسی ² (دانشگاه آزاد اسلامی، واحد دامغان، گروه زیست شناسی، دامغان، ایران)
عبدالحسین  شیروی ³ (دانشگاه آزاد اسلامی، واحد دامغان، گروه زیست شناسی، دامغان، ایران)
مهسا  پورکاظم ⁴ (دانشگاه آزاد اسلامی، واحد دامغان، گروه زیست شناسی، دامغان، ایران)
فرشته  علی آبادی ⁵ (دانشگاه آزاد اسلامی، واحد دامغان، گروه زیست شناسی، دامغان، ایران)

Received: 2014-06-22 Accepted : 2017-05-21 Published : 2011-01-21

Keywords: Mice, Detergent, chlorine, Bleach, Leukocyte, Inhalation,

Abstract :

Today,bleachandcleaningmaterialsarethemost commonproductsthatareused bythe public.Sometimes amixtureofbleachanddetergentsforcleaninguse someoftheChemistryof thefurtherrelease ofchlorine gaspoisoningandthesymptomsaresevere.Chlorinegashas been knownas a mucus membranes and respiratory tract irritant .This gas can increase free radicals. Free radicalscancausecell damage.Theeffects ofinhalingthe gasanditsconsumptiononbody tissuesandbloodcells,complete informationis available The aimof this studythe effects ofinhalingtoxicmaterials,bleachanddetergentmixtureofbloodcellsinthemice.42adult male mice NMRIweighing35andplusmn;3 g and10 to 8weeksto6 groupswere divided intoexperimentalandcontrolgroups. Experimentalgroup1 - 2 -3 withthechamberaglass(chamber)to beinhaledfor 20 minutestosprayamixtureof1 ccof bleachanddetergent were usedby thenebulizer.Experimentalgroups4-5-6, 35minutestoinhalethe same amountofmaterialreceivedmiceat24 to 48-72 hoursafterinhalationofblood sampling, they werethenGiemsastainedslidespreparedandexaminedNewbury.Thestudywasdoneby increasing theexposuretimeincreasedsignificantly thenumber ofleukocytesanderythrocyteswere foundtohavebeentransformed.Increasedduration ofexposure toa mixture ofbleachanddetergent, and over time changesincreased thenumber ofleukocytes.