Acute Toxicity, Brine Shrimp Lethality and Phytochemical Screening of Lannea schimperi and Searsia longipes

Subject Areas : Journal of Chemical Health Risks

Musa Chacha ¹ , Nicolaus Mbugi ²

1 - Nelson Mandela African Institution of Science and Technology, Tanzania
2 - Nelson Mandela African Institution of Science and Technology, Tanzania

Received: 2018-11-07 Accepted : 2019-03-20 Published : 2019-06-01

Keywords:

References:

1. Maroyi A., 2011. An Ethnobotanical Survey of Medicinal Plants Used by the People in Nhema Communal Area, Zimbabwe. J. Ethnopharmacol. 136(2), 347–54. Retrieved (http : // dx.doi.org / 10.1016 / j. jep. 2011 . 05 . 003)

2. Okoth D.A., 2014. Phytochemistry and Bioactive Natural Products from Lannea Alata, Lannea rivae, Lannea schimperi and Lannea schweinfurthii (Anacardiaceae ). Phd Thesis, University of Kwazulu-Natal, South Africa.

3. Moshi M.J., Mbwambo Z.H., 2002. Experience of Tanzanian Traditional Healers in the Management of Non-Insulin Dependent Diabetes Mellitus. Pharm Biol. 40(7), 552–560.

4. Kisangau D.P., Lyaruu H.V., Hosea K.M., Joseph C.C., 2007. Use of Traditional Medicines in the Management of HIV/AIDS Opportunistic Infections in Tanzania: A Case in the Bukoba Rural District. J Ethnobiol Ethnomed. 3,1-8.

5. Chinsembu K.C., Hedimbi M., 2010. An Ethnobotanical Survey of Plants Used to Manage HIV/AIDS Opportunistic Infections in Katima Mulilo, Caprivi Region, Namibia. J Ethnobiol Ethnomed. 6, 1-9.

6. Moshi M.J., Mbwambo Z.A., Nondo R.S., Masimbaa P.J., Kamuhabwa A., Kapingu M. C., Thomas P., Richard M., 2006. Evaluation of Ethnomedical Claims and Brine Shrimp Toxicity of Some Plants Used in Tanzania as Traditional Medicines. African J. Tradit Complement. Altern Med. 3(3), 48-58.

7. Jeruto P., Lukhoba C., Ouma G., Otieno D., Mutai C., 2008. An Ethnobotanical Study of Medicinal Plants Used by the Nandi People in Kenya. J Ethnopharmacol. 116(2), 370-376.

8. Egbe E.O., Akumka D.D., Adamu M., Mikail H.G., 2015. Phytochemistry, Antinociceptive and Anti-inflammatory Actvities of Methanolic Leaves Extract of Lannea schimperi (Hoschst. Ex Rich) ENG. Recent Pat. Biotechnol. 9(2), 145-152.

9. Sherfi T.K., Ibrahim A.A., Ahmed A.A.A., Omer G., 2016. Phyto-Constituents and Antioxidant Activity of Rhus abyssinica, Heeria insignis and Lannea schimperi (Anacardiaceae family). Eur Acad Res. 4(8), 6493 - 6509.

10. Haule E.E., Moshi M.J., Nondo R.S., Mwangomo D.T., Mahunnah R.L., 2012. A study of antimicrobial activity, acute toxicity and cytoprotective effect of a polyherbal extract in a rat ethanol-HCl gastric ulcer model. BMC Res Notes. 5(1), 1-9.

11. Djakpo O., Yao W., 2010. Rhus Chinensis and Galla Chinensis – Folklore to Modern Evidence: Review Phytother Res. 24, 1739–1747.

12. Miller A.J., Young D.A., Wen J., 2001. Phylogeny and Biogeography of Rhus (Anacardiaceae ) Based on ITS Sequence Data. Int J Plant Sci. 162(6), 1401–1407.

13. Duke J.A., Ayensu E.S., 1985. Medicinal Plants of China. Vol. 2. Algonac, MI.

14. Kuo S.C., Teng C.M., Lee L.G., Chiu T.H., Wu T.S., Huang S.C., Wu J.B., Shieh T.Y., Chang R.J., Chou T. C., 1990. 6-Pentadecylsalicylic Acid; An Antithrombin Component Isolated from the Stem of Rhus semialata var. roxburghii. Planta Med. 57(3), 247-249.

15. Ouyang M.A., Chang C.I., Wein Y.S., Kuo Y.H., 2008. New Phenol Glycosides from the Roots of Rhus Javanica Var. Roxburghiana. J Chin Chem. Soc. 55(1), 223-227.

16. Abbasi A.M., Khan M.A., Ahmad M., Zafar M., Khan H., Muhammad N., Sultana S., 2009. Medicinal Plants Used for the Treatment of Jaundice and Hepatitis Based on Socio-Economic Documentation. Afr J Biotechnol. 8(8), 1643–1650.

17. Abbassi F., Hani K., 2012. In vitro antibacterial and antifungal activities of Rhus tripartitum used as antidiarrhoeal in Tunisian folk medicine. Nat Prod Res. 26(23), 2215-2218.

18. Kuma F., Birhanu T., Hirpa E., Nekemte E., 2015. Advanced Review on Anthelmintic Medicinal Plants. Rep Opin. 7(5), 6-16.

19. Tlili N., Mejri H., Yahia Y., Saadaoui E., Rejeb S., Khaldi A., Nasri N., 2014. Phytochemicals and Antioxidant Activities of Rhus Tripartitum (Ucria) Fruits Depending on Locality and Different Stages of Maturity. Food Chem. 160, 98–103.

20. Mtunzi F.M., Ejidike I.P., Matamela T., Dikio E., Klink M.J., 2017. Phytochemical Profiling , Antioxidant and Antibacterial Activities of Leaf Extracts from Rhus Leptodictya. International Journal of Pharmacognosy and Phytochemical Research. Int J Phytochem Pharmacol Res. 9(8), 1090–1099.

21. Anwer T., Sharma M., Khan G., Iqbal M., Ali M.S., Alam M.S., Safhi M.M., Gupta N., 2013. Rhus coriaria ameliorates insulin resistance in non-insulin-dependent diabetes mellitus (NIDDM) rats.
Acta Pol Pharm. 70(5), 861-867.

22. Abu-Reidah I.M., Ali-Shtayeh M.S., Jamous R.M., Arráez-Román D., Segura-Carretero A., 2015. HPLC-DAD-ESI-MS/MS Screening of Bioactive Components from Rhus Coriaria L. (Sumac) Fruits. Food Chem.166, 179–191.

23. OECD., 2001. Guidance Document on Acute Oral Toxicity Testing. OECD Guidel. Test. Chem.

24. Meyer B.N., Ferrigni N.R., Putnam J.E., Jacobsen L.B., Nichols D.E., McLaughlin J.L., 1982. Brine Shrimp: A Convenient General Bioassay for Active Plant Constituents. Planta Med. 45(5), 31-34.

25. Gul R., Jan S.U., Faridullah S., Sherani S., Jahan N., 2017. Preliminary Phytochemical Screening, Quantitative Analysis of Alkaloids, and Antioxidant Activity of Crude Plant Extracts from Ephedra intermedia Indigenous to Balochistan. Sci World J. 2017, 1-7.

26. Olorunnisola O. S., Adetutu A., Owoade A. O., Adesina B. T., Adegbola P., 2017. Toxicity evaluation and protective effect of Rhus longipes Engl. leaf extract in paracetamol induced oxidative stress in wister rats. J Phytopharmacol. 6(2),73–77.

27. Diallo A., Eklu-Gadegkeku K., Mobio T., Moukha S., Agbonon A., Aklikokou K., Creppy E.E., Gbeassor M., 2009. Protective effect of Moringa oleifera Lam. and Lannea kerstingii extracts against cadmium and ethanol-induced lipid peroxidation. J Pharmacol Toxicol.4(4), 160-166.

28. Sanchez C., Gupta M., Vasquez M., Montenegro G., 1993. Bioessay with Brine Artemia to Predict Antibacterial and Pharmacologic Activity. Rev Med Panama. 18(1), 62-69.

29. Gabr S.A., Alghadir A.H., 2015. Phytochemical analysis and in vitro antifungal activities of bioactive fractions from leaves of Rhus coriaria (SUMAC). J Pure Appl Microbiol. 9, 559-565.