Study of Opportunistic Infections in Diabet Mellitus patients in Islamic Azad University Hospitals

Subject Areas : Medical Microbiology

Mohammad Karim  Rahimi ¹ (Microbiology and Biology Department, Islamic Azad University, Parand Branch, Parand, Iran)
Saeed  Zaker Bostanabad ² (Microbiology and Biology Department, Islamic Azad University, Parand Branch, Parand, Iran)
Talieh  Hashemizonooz ³ (Microbiology Department, Islamic Azad University, Tehran Medical Branch, Tehran, Iran)
Mohammad  Bossak ⁴ (Laboratory of Microbiology, Islamic Azad University, Tehran Medical Branch, Tehran, Iran)
Parvaneh  Adimi ⁵ (Laboratory of Microbiology, Islamic Azad University, Tehran Medical Branch, Tehran, Iran)
Mozhghan  Masoumi ⁶ (Laboratory of Microbiology, Islamic Azad University, Tehran Medical Branch, Tehran, Iran)
Zahra  Tayebi ⁷ (Laboratory of Microbiology, Islamic Azad University, Tehran Medical Branch, Tehran, Iran)

Received: 2009-04-14 Accepted : 2009-05-15 Published : 2009-04-01

Keywords: Opportunistic infections, Diabet mellitus, Blood sugar, Blood Urea Nitrogen,

Abstract :

Background and Objective: Diabet mellitus is a chronic disease. In this disorder, due to abnormal glucose metabolism, direct and indirect complications in many organ systems, including ocular, cardio-vascular, vernal, and cerebral and suppression of immune system have been occurred. Decreasing of both cellular and humoral immune system is a important factor for opportunistic infections. Prevention and control of these infections and recognize of their frequency and risk factor is very important. Material and Methods: In this study, 118 diabetic patients that admitted in Islamic Azad University hospitals were included. Chief complaint of every patient, important finding in clinical examinations and results of microbial culturing from opportunistic infections had been analyzed. Result: From 118 patients, 65 cases (55%) were female and 53 cases (45%) were male. Mean age of patients was 59.6 ± 11.7 years old and mean duration time of disease was 13.6 ± 7.8 years. Thirty one cases (26.1%) infected by opportunistic bacterial. From patient's samples (in microbial culturing), 12 cases (38.5%0 Escherichia coli, 9 cases (29%) fungal pathogens, 5 cases (16.3%0 staphylococcus aurous and 5 cases (16.3%0 Pseudomonas aeruginosa were isolated. Conclusion: Because of high frequency of infections in diabetic patients, using of preventing methods is important. On the other hand, diagnostic and treatment of these infections prevent from their complications.