Comparison of the histopathological effects of acepromazine and xylazine as premedication on liver in Pigeon
Subject Areas : Histology
1 - department of veterinary medicine
Keywords: liver, Histopathology, pigeon, ketamine acepromazine xylazine,
Abstract :
The goal of performing this research was to review and compare histopathological effects of acepromazine and xylazine as a pre-anesthetic drug on liver tissue in pigeon. So, we used 18 clinically healthy male pigeons in the age range 8 to 12 months and their weight was between 300 to 450 g. The first group considered as the witness group and they were injected 30 mg/kg ketamine. And the second group were injected 1 mg/kg acepromazine intramuscularly and after 10 minutes, they were injected 30 mg/kg ketamine. The third group were injected 5 mg/kg xylazine and 10 minutes after that, they were injected 30 mg/kg ketamine. 24 hours after the injections, tissue samples were taken frome the pigeons' liver and histopathological reviews were performed. In histopathological reviews, the three groups' livers showed a normal situation but we witnessed a mild hyperemia in the second group and a mild mononuclear infiltration in kidney interstitum in the second and third group around the portal. The results of this research, for the first time showed that the use of acepromazine – ketamine and xylazine – ketamine anesthetic regimens in pigeons, does not cause any considerable histopathological damage in liver tissue.
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