اثرات کود سدیمی و آفلاتوکسین B1 بر وزن بدن جوجههای گوشتی
Subject Areas : Camel
1 - Institute of Nutrition, Dietetics and Feed Production, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic
2 - Department of Hygiene and Food Industry Technology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic
Keywords: جوجه گوشتی, آلکالین فسفاتاز, آفلاتوکسین B1, وزن بدن جوجهها, کود سدیم,
Abstract :
هدف از این مطالعه بررسی اثر محافظتی کود طبیعی جاذب سدیم (HuNa) در جیره بر پیشگیری از اثر سمیت آفلاتوکسین B1 (AFB1) در جوجههای گوشتی بود. 72 جوجه گوشتی آمیخته هایبرو به صورت تصادفی در 4 گروه تقسیم شدند: گروه کنترل (G1) و سه گروه آزمایشی (G2 تا G4) با افزودن HuNa (G2)، تنها AFB1 (G3) و HuNa و AFB1 (G4). HuNa به مخلوط خوراک کامل برای جوجهها افزوده شد (با نسبت 1 گرم HuNa در هر 100 گرم مخلوط خوراک). AFB1 نیز با غلظت 25 میکروگرم در هر کیلوگرم وزن بدن افزوده گردید. پارامترهای ارزیابی شده عبارت از وزن بدن و سطوح سرمی آلکالین فسفاتاز (ALP) بود. AFB1 و HuNa برای جوجههای گوشتی از 28 روزگی به کار گرفته شدند. کاهش معنیدار آماری در فعالیت ALP (05/0>P) در گروه G3 در مقایسه با گروه G1 جوجههای گوشتی از 42 تا 56 روزگی به بعد مشاهده شد. ولی افزایش معنیدار آماری در فعالیت ALP (05/0>P) در گروه G4 در مقایسه با گروه G1 مشاهده گردید. وزن بدن جوجههای گوشتی پس از قرار گرفتن در معرض AFB1 (G3) در مقایسه با شاهد (G1) حدود 180 گرم پایینتر بود. همچنین افزودن HuNa سبب افزایش وزن بدن جوجههای گوشتی تا حدود 67/26 گرم در انتهای آزمایش در مقایسه با گروه شاهد گردید. افزایش معنیدار آماری (05/0>P) در وزن بدن برای گروه G3 و G4 در سن 56 روزگی در مقایسه با سن 28 روزگی ثبت گردید. نتایج این آزمایش نشان میدهند که HuNa اثر مثبتی بر رشد جوجههای گوشتی داشته و میتواند یک افزودنی طبیعی مناسب برای رشد جوجههای گوشتی در برابر اثرات زیانآور آفلاتوکسینها باشد.
Abo-Norag M., Edrington T.S., Kubena L.F. and Harvey R.B. (1995). Influence of a hydrated sodium calcium aluminosilicate and virginiamycin on aflatoxicosis in broiler chicks. Poult. Sci. 74, 626-632.
Beers K.W., Glahn R.P., Bottje G.W. and Huff W.E. (1992). Aflatoxin and glutathione in domestic fowl (Gallus Domesticus) II. Effects on hepatic blood flow. Comp. Biochem. Phys. 101, 463-467.
Blahovec J. and Šlesárová L. (1991). Enzymes and Clinical Enzymology (Slovak langue). Zenit Press, Košice, SlovakRepublic.
Cheng Y.H., Shen T.F., Pang V.F. and Chen B.J. (2000). Effects of aflatoxin and carotenoids on growth performance and immune response in mule ducklings. Comp. Biochem. Phys. 128, 19-26.
Decree of the Ministry of Agriculture of the Slovak Republic No. 440. (2006). Requirements on Technological Proceedings and Index Nutrition of Food Mixtures.
Denli M., Okan F. and Doran F. (2004). Effect of conjugated linoleic acid (CLA) on the performance and serum variables of broiler chickens intoxicated with aflatoxin B1. South. African J. Anim. Sci. 34(2), 97-103.
Denli M. and Okan F. (2006). Efficacy of different adsorbent in reducing the toxic effects of aflatoxin B1 in broiuler diets. South African J. Anim. Sci. 36(4), 222-228.
Desheng Q., Fan L., Yanhu Y. and Niya Z. (2005). Adsorption of aflatoxin B1 on montmorillonite. Poult. Sci. 84(6), 959-961.
Diaz G.J., Calabrese E. and Blain R. (2008). Aflatoxicosis in chickens (Gallus gallus): an example of hormesis? Poult. Sci. 87(4), 727-732.
Doerr J.A., Huff W.E., Wabeck C.J., Chaloupka G.W., May J.D. and Merkley J.W. (1983). Effects of low level chronic aflatoxicosis in broiler chikens. Poult. Sci. 62, 1971-1977.
Edrington T.S., Kubena L.F., Harvey R.B. and Rottinghaus G.E. (1997). Influence of a superactivated charcoal on the toxic effects of aflatoxin or T-2 toxin in growing broilers. Poult. Sci. 76, 1205-1211.
Espada Y., Domingo M., Gomez J. and Calvo M.A. (1992). Pathological lesions following an experimental intoxication with aflatoxin B1 in broiler chickens. Res. Vet. Sci. 53, 275-279.
FernandezN.J. and Kidney B.A. (2007). Alkaline phosphatase: beyond the liver. Vet. Clin. Pathol. 36(3), 223-233.
Garaleviciene D., Pettersson H., Augonyte G., Elwinger K. and Lindber J.E. (2001). Effects of moulds and toxin contaminated barley on laying hen’s performance and health. Arch. Tierernahr. 55, 25-42.
Gawai K.R., Vodela J.K., Dalvi P.S. and Dalvi R.R. (1992). Comparative assessment of the effect of aflatoxin B1 on hepatic dysfunction in some mammalian and avian species. Comp. Biochem. Physiol. 101, 415-418.
Ghahri H., Habibian R. and Fam M.A. (2010). Effect of sodium bentonite, mannan oligosaccharide and humate on performance and serum biochemical parameters during aflatoxicosis in broiler chickens. Glob. Vet. 5(2), 129-134.
Ghosh R., Banerjee D.K. and Ghosh R. (1997). Complexation of trace elements with humic acids from soil, sediment and sewage. Chem. Speciation Bioavail. 9, 15-19.
Giambrone J.J., Diáener U.l., DavisN.D., Panangala V.S. and Hoerr F.J. (1985). Effects of purified aflatoxin on broiler chickens. Poult. Sci. 64, 852-858.
Huwig A., Freimund S., Käppeli O. and Dutler H. (2001). Mycotoxin detoxication of a animal feed by different adsorbents. Toxicol. Lett. 122, 179-188.
Jansen van Rensburg C., Van Rensburg C.E.J., Van Ryssen J.B.J., Casey N.H. and Rottinghaus G.E. (2006). In vitro and in vivo assessment of humic acid as an aflatoxin binder in broiler chickens. Poult. Sci. 85, 1576-1583.
Jindal N., Mahipal S.K. and Mahajan N.K. (1993). Effect of hydrate sodium calcium aluminosilicate on prevention of aflatoxicosis in broilers. Indian J. Anim. Sci. 63, 649-652.
Kaplan M.M. (1987). Laboratory tests. Pp. 219 in Diseases of the Liver. L. Schiff, E.R. Schiff and J.B. Lippincott, Eds. Philadelphia, USA.
Klein P.J., Vleet T.R., Hall J.O. and Coulombe R.A. (2002). Dietary butylated hydroxytoluene protects against aflatoxicosis in turkey. Toxicol. Appl. Pharmacol. 182, 1078-1303.
Kubena L.F., Harvey R.B., Bailey R.H., Buckley S.A. and Rottinghaus G.E. (1998). Effects of a hydrated sodium calcium aluminosilicate (T-Bind) on mycotoxicosis in young broiler chickens. Poult. Sci. 77, 1502-1509.
Madden U.A., Stahr H.M. and Stino F.K. (1999). Effect on performance and biochemical parameters when soil was added to aflatoxin-contaminated poultry rations. Vet. Hum. Toxicol. 41, 213-221.
Miazzo R., Peralta M.F., Magnoli C., Salvano M., Ferrero S., Chiacchiera S.M., Carvalho E.C.Q., Rosa C.A.R. and Dalcero A. (2005). Efficacy of sodium bentonite as a detoxifier of broiler feed contaminated with aflatoxin and fumonisin. Poult. Sci. 84, 1-8.
Oliveira C.A.F., Rosmaninho J.F., Butkeraitis P., Correa B., Reis T.A., Guerra J.L., Albuquerque S.R. and Moro M.E.G. (2002). Effect of low levels of dietary aflatoxin B1 on laying Japanese quail. Poult. Sci. 81, 976-980.
Park D.L. (2002). Effect of processing on aflatoxin. Adv. Exp. Med. Biol. 504, 173-179.
Phillips T.D., Sarr A.B., Grant P.G., Van-Egmont H.P., Visconti A., Boenke A. and Speijers G.J.A. (1994). Selective chemisorption and detoxification of aflatoxins by phyllosilicate clay. Pp. 204-213 in Proc. Int. Workshop. Held.Nat. Toxin. Lisbon, Portugal.
Písaříková B., Zralý Z. and HerzigI. (2010). The effect of dietary sodium humate supplementation on nutrient digestibility in growing pigs. Acta Vet. Brno.79, 349-353.
Pittet A. (1998). Natural occurrence of mycotoxins in foods and feeds-an updated review. Rev. Med. Vet. 49, 479-492.
Raina J.S., Roy K.S. and Singh B. (1991). Biochemical and histochemical studies in experimental mycotoxicosis in chicks. Indian J. Anim. Sci. 62, 1276-1293.
Rauber R.H., Dilkin P., Giacomini L.Z., Araújo de Almeida C.A. and Mallmann C.A. (2007). Performance of turkey poults fed different doses of aflatoxins in the diet. Poult. Sci. 86, 1620-1624.
Rosa C.A., Miazzo R., Magnoli C., Salvano M., Chiacchiera S.M., Ferrero S., Seanz M., Carvalho E.C. and Dalcero A. (2001). Evaluation of the efficacy of bentonite from the south of Argentina to ameliorate the toxic effects of aflatoxin in broilers. Poult. Sci. 80, 139-144.
Sadeghi A.A., Saei M.M., Nikkhah A. and Ahmadvand H. (2013). The effect of Myrtus communis oil extract on growth performance, serum biochemistry and humoral immune responses in broiler chicks fed diet containing aflatoxin B1. Arch. Tierz. 56(84), 1-12.
Sehu A., Ergun L., Cakir S., Ergun E., Cantekin Z., Sahin T., Essiz D., Sreyyupoglu B., Gurel Y. and Yigit Y. (2007). Hydrated sodium calcium aluminosilicate for reduction of aflatoxin in quails (Coturnix coturnix japonica). Deutsch. Tierarztl. Wochenschr. 114, 252-259.
Sheng-Qun Y., Xing-Zuo L. and An-Guo Z. (2009). In vitro evaluation of the efficacy of sodium humate as an aflatoxin B1 adsorbent. Australian J. Bas. Appl. Sci. 3(2), 1296-1300.
Skalická M., Koréneková B., Naď P. and Makóová Z. (2002a). The role of natrium humate on cadmium elimination and copper level in poultry. Chem. Inžyn. Ekolog. 9, 1251-1255.
Skalická M., Koréneková B., Jacková A., Kottferová J. and Ondrašovič M. (2002b). The importance of sorbents in elimination of xenobiotics from the environment. Fol. Vet. 46, 169-170.
Spark K.M., Wells J.D. and Johnson B.B. (1997). Sorption of heavy metals by mineral humic substrates. Australian J. Soil. Res. 35, 113-122.
Sutabhaha S., Suttajit M. and Niyomca P. (1992). Studies of aflatoxins in Chiang Mai, Thailand. Kitasato Arch. Exp. Med. 65, 45-52.
Tessari E.N., Oliveira C.A., Cardoso A.L., Ledoux D.R. and Rottinghaus G.E. (2006). Effects of aflatoxin B1 and fumonisin B1 on body weight, antibody titres and histology of broiler chicks. Poult. Sci. 47, 357-364.
Yousef M.I., Salem M.H., Kamel K.I., Hassan G.A. and El-Nouty F.D. (2003). Influence of ascorbic acid supplementation on the haematological and clinical biochemistry parameters of male rabbits exposed to aflatoxin B1. J. Environ. Sci. Health B. 38, 193-209.
Verma J., Johri T.S. and Swain B.K. (2003). Effect of varying levels of aflatoxin, ochratoxin and their combinations on the performance and egg quality characteristics in laying hens. Asian-Australas J. Anim. 167, 1015-1019.
Williams J.H., Philips T.D., Jolly P.E., Stiles J.K., Jolly C.M. and Aggarwal D. (2004). Human aflatoxicosis in developing countries: a review of toxicology, exposure, potential health consequences and interventions. Am. J. Clin. Nutr. 80, 1106-1122.