آنالیز فرود ژنی بنیانگذاران و تنوع آللی در یک جمعیت تحت انتخاب بلدرچین ژاپنی
Subject Areas : Camel
1 - Department of Animal Science, Faculty of Agriculture, Lorestan University, Khorram-Abad, Iran
2 - Department of Animal Science, Faculty of Agricultural Science, Payame Noor University, Tehran, Iran
Keywords: تنوع ژنتیکی, بلدرچین ژاپنی, بنیانگذار, فرود ژنی,
Abstract :
این مطالعه برای بررسی آنالیز شجره و دراپ ژنی جهت نمایش تنوع ژنتیکی و توصیه یک استراتژی انتخاب برای بهبود وزن سینه در یک جمعیت بلدرچین ژاپنی انجام شد. تعداد 312 پرنده به دو گروه مساوی تقسیم شدند. یک لاین (S1) برای وزن چهار هفتگی بدن بر اساس ارزش‌های اصلاحی و دیگری (S2) برای وزن سینه در چهار هفتگی بر اساس انتخاب بین خانوادگی، انتخاب شدند. توزیع فراوانی‌های آللی حاصل از بنیانگذاران با استفاده از شجره هر لاین در نرم افزار شبیه‌ساز دراپ ژنی تخمین زده شد. نتایج نشان داد بهبود ژنتیکی خالص برای وزن بدن و وزن سینه در لاین‌های S1 و S2 به ترتیب 3/28 و 7/9 گرم در مقابل 3/23 و 8/6 گرم بود. میانگین تعداد آلل‌های باقیمانده برای آخرین نسل لاین‌های S1 و S2به ترتیب 6/59 و 2/31 بود که به ترتیب 1/19 و 10 درصد کل آلل‌های اختصاص یافته به جمعیت پایه هر لاین بود. می‌توان نتیجه‌گیری نمود که برای تداوم پاسخ به انتخاب جهت بهبود وزن سینه، انتخاب غیر مستقیم وزن بدن بر اساس ارزش‌های اصلاحی قابل توصیه است. نتایج حاصل از آنالیز دراپ ژنی آشکار نمود که در این تحقیق انتخاب بین خانوادگی پیشرفت ژنتیکی بیشتر و تنوع ژنتیکی باقیمانده بیشتری نسبت به انتخاب انفرادی بر اساس ارزش‌های اصلاحی ندارد.
Baes C. and Reinsch N. (2008). TIGER: A software system for fine-mapping quantitative trait loci. Arch. Tierzucht. 51(4), 402-412.
Blackburn H. (2012). Genetic selection and conservation of genetic diversity. Reprod. Domest. Anim. 47(4), 249-254.
Berg P. (2010). EVA version 1.3. http://eva.agrsci.dk. Accessed Mar. 2013.
Boichard D., Maignel L. and Verrier E. (1997). The value of using probabilities of gene origin to measure genetic variability in a population. Genet. Sel. Evol. 29, 5-23.
Caballero A. and García-Dorado A. (2013). Allelic diversity and its implications for the rate of adaptation. Genetics. 195(4), 1373-1384.
Caballero A. and Hill W. (1992). Effective size of nonrandom mating populations. Genetics. 130(4), 909-916.
Carlborg Ö., Jacobsson L., Åhgren P., Siegel P. and Andersson L. (2006). Epistasis and the release of genetic variation during long-term selection. Nat. Genet. 38, 418-420.
Falconer D.S., Mackay T.F. and Frankham R. (1996). Introduction to Quantitative Genetics. Benjamin Cummings, Wilmington, Delaware, USA.
Fernández J., Villanueva B., Pong-Wong R. and Toro M.A. (2005). Efficiency of the use of pedigree and molecular marker information in conservation programs. Genetics. 170(3), 1313-1321.
Frankham R., Ballou G.D. and Briscoe D.A. (2002). Introduction to conservation genetics. Cambridge University Press. Cambridge, United Kingdom.
Gilmour A.R., Cullis B.R., Welham S.J. and Thompson R. (2000). ASReml Users' Manual. New South Wales Agriculture, Orange, Australia.
Goddard M. and Smith C. (1990). Optimum number of bull sires in dairy cattle breeding. J. Dairy Sci. 73(4), 1113-1122.
Gutié J.P., Cervantes I., Molina A., Valera M. and Goyache F. (2008). Individual increase in inbreeding allows estimating effective sizes from pedigrees. Genet. Sel. Evol. 40(4), 359-378.
Hill W.G. (2000). Maintenance of quantitative genetic variation in animal breeding programmes. Livest. Prod. Sci. 63(2), 99-109.
Honda T., Nomura T., Fukushima M. and Mukai F. (2002). Gene dropping analysis of founder contributions in a closed Japanese black cattle population. Anim. Sci. J. 73(2), 105-111.
Javanmard A., Mohammadabadi M.R., Zarrigabayi G.E., Gharahedaghi A.A., Nassiry M.R., Javadmansh A. and Asadzadeh N. (2008). Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus). Russian J. Genet. 44(4), 495-497.
Khaldari M., Pakdel A., Mehrabani Yegane H., Nejati Javaremi A. and Berg P. (2010). Response to selection and genetic parameters of body and carcass weights in Japanese quail selected for 4-week body weight. Poult. Sci. 89(9), 1834-1841.
Lacy R.C. (1995). Clarification of genetic terms and their use in the management of captive populations. Zoo Biol. 14(6), 565-577.
Lange K., Cantor R., Horvath S., Perola M., Sabatti C., Sinsheimer J. and Sobel E. (2001). Mendel version 4.0: a complete package for the exact genetic analysis of discrete traits in pedigree and population data sets. Am. J. Hum. Genet. 69(1), 1886.
MacCluer J.W., VandeBerg J.L., Read B. and Ryder O.A. (1986). Pedigree analysis by computer simulation. Zoo Biol. 5(2), 147-160.
Man W., Nicholas F. and James J. (2007). A pedigree-analysis approach to the descriptive epidemiology of autosomal-recessive disorders. Prev. Vet. Med. 78(3), 262-273.
Melka M., Sargolzaei M., Miglior F. and Schenkel F. (2012). Genetic diversity of Guernsey population using pedigree data and gene-dropping simulations. Animal. 7(2), 192-201.
Meuwissen T. (2009). Genetic management of small populations: A review. Acta. Agric. Scandinavica. 59(2), 71-79.
Mohammadabadi M.R., Nikbakhti M., Mirzaee H.R., Shandi A., Saghi D.A., Romanov M.N. and Moiseyeva I.G. (2010). Genetic variability in three native Iranian chicken populations of the Khorasan province based on microsatellite markers. Russian J. Genet. 46(4), 505-509.
Moradian H., Esmailizadeh A.K., Sohrabi S. and Mohammadabadi M.R. (2015). Identification of quantitative trait loci associated with weight and percentage of internal organs on chromosome 1 in Japanese quail. J. Agric. Biotechnol. 6(4), 143-158.
Moradian H., Esmailizadeh A.K., Sohrabi S.S., Nasirifar E., Askari N., Mohammadabadi M.R. and Baghizadeh A. (2014).
Genetic analysis of an F2 intercross between two strains of Japanese quail provided evidence for quantitative trait loci affecting carcass composition and internal organs. Mol. Biol. Rep. 41(7), 4455-4462.
Nomura T., Honda T. and Mukai F. (2001). Inbreeding and effective population size of Japanese Black cattle. J. Anim. Sci. 79(2), 366-370.
Ori R.J., Esmailizadeh A.K., Charati H., Mohammadabadi M.R. and Sohrabi S.S. (2014). Identification of QTL for live weight and growth rate using DNA markers on chromosome 3 in an F2 population of Japanese quail. Mol. Biol. Rep. 41(2), 1049-1057.
Ruzina M.N., Shtyfurko T.A., Mohammadabadi M.R., Gendzhieva O.B., Tsedev T. and Sulimova G.E. (2010). Polymorphism of the BoLA-DRB3 gene in the Mongolian, Kalmyk, and Yakut cattle breeds. Russian J. Genet. 46(4), 456-463.
Sohrabi S.S., Esmailizadeh A.K., Baghizadeh A., Moradian H., Mohammadabadi M.R., Askari N. and Nasirifar E. (2012). Quantitative trait loci underlying hatching weight and growth traits in an F2 intercross between two strains of Japanese quail. Anim. Prod. Sci. 52(11), 1012-1018.
Sölkner J., Filipcic L. and Hampshire N. (1998). Genetic variability of populations and similarity of subpopulations in Austrian cattle breeds determined by analysis of pedigrees. Anim. Sci. 67(2), 249-256.
Sonesson A.K. and Meuwissen T.H.E. (2000). Maring schemes for optimum contribution selection with constrained rates of inbreeding. Genet. Sel. Evol. 32(3), 231-238.
Sørensen M.K., Sørensen A.C., Baumung R., Borchersen S. and Berg P. (2008). Optimal genetic contribution selection in Danish Holstein depends on pedigree quality. Livest. Sci. 118(3), 212-222.
Suwanlee S., Baumung R., Sölkner J. and Curik I. (2007). Evaluation of ancestral inbreeding coefficients: Ballou’s formula versus gene dropping. Conserv. Genet. 8(2), 489-495.
Trinderup M., Jorgensen J.N. and Hansen M. (1999). Conservation considerations on Danish Shorthorn cattle using pedigree analysis. Anim. Gen. Res. Inf. 26, 27-33.
Varkoohi S., Babak M.M.S., Pakdel A., Javaremi A.N., Zaghari M. and Kause A. (2010). Response to selection for feed conversion ratio in Japanese quail. Poult. Sci. 89(8), 1590-1598.
Wright S. (1969). The Theory of Gene Frequencies. The University of Chicago Press, Chicago, USA.
Yamashita J., Hironori O., Hasegawa T., Honda T. and Nomura T. (2010). Gene dropping analysis of ancestral contributions and allele survival in Japanese thoroughbred population. J. Equin Sci. 21(3), 39-45.
Zhao G., Chen J., Zheng M., Wen J. and Zhang Y. (2007). Correlated responses to selection for increased intramuscular fat in a Chinese quality chicken line. Poult. Sci. 86(11), 2309-2314.
