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Open Access Article
1 - Evaluation of Cichoric Acid of Echinacea purpurea Extract under Different Ecological Conditions in Semnan Province Iran
Elahe Rostami Bahareh Kashefi Nahid MasoudianEchinacea purpurea is an herbaceous perennial plant as members of the Asteraceae family. It is one the important medicinal plant in pharmacy industrial. Active substances of Echinaceae are amplifier of body's immune system and antivirus. Echinacea is not native to Iran. MoreEchinacea purpurea is an herbaceous perennial plant as members of the Asteraceae family. It is one the important medicinal plant in pharmacy industrial. Active substances of Echinaceae are amplifier of body's immune system and antivirus. Echinacea is not native to Iran. The phytochemical traits of medicinal plants depend on ecological conditions involving growing areas, climate conditions; various grow stages and genetic modifications. The aim of this study was the evaluation of cichoric acid of E. purpurea extract in different ecological conditions in Semnan, Iran. Dormancy in seeds was broken by treating them with strafication in 4 °C for 48 h, was grown in nursery beds for autumn and early winter and transfered to four areas with different ecological conditions in late winter. Chashm, Ahuvan, Semnan and Foladmahale were chosen for this experiment. The spacing of plantlet was about 25 × 45 cm in the field. After 2- 3 months, aerial parts of the plants collected in all areas and extract samples were prepared and characterized using high- performance liquid chromatography (HPLC). The components of a basic HPLC system were shown significant values of the cichoric acid in plants under four habitats. The level of cichoric acid in one condition was more than standards level that reported in another references. In addition, ecological diversities have significant impacts the quantity of cichoric acid in E. purpurea.   Manuscript profile -
Open Access Article
2 - Evaluation of Removal Efficiency of Cr (VI) Ions from Aqueous Solution Using Chitosan
Soheil Sobhanardakani Raziyeh Zandipak Mohadeseh Bonyadi Hassan Parvizimosaed Mehran Moslemi Mahsa Tahergorabi Tahergorabi Seyed Mehdi HosseiniIn this research, chitosan was used for the removal of Cr (VI) ions from aqueous solution. The effect of parameters like solution pH, initial Cr (VI) concentration, agitation time, amount of adsorbent and agitation speed on the adsorption process was studied. The experi MoreIn this research, chitosan was used for the removal of Cr (VI) ions from aqueous solution. The effect of parameters like solution pH, initial Cr (VI) concentration, agitation time, amount of adsorbent and agitation speed on the adsorption process was studied. The experimental equilibrium data were analyzed by using various models such as Langmuir and Freundlich. Freundlich isotherm model fitted well with data. In addition, the experimental data was fitted to kinetic models including the pseudo-first-order and pseudo-second-order and based on calculated respective parameters such as rate constants, equilibrium adsorption capacities and correlation coefficients. The removal process follows the pseudo-second-order kinetic model. The results suggest that chitosan could be employed as a low-cost material for the removal of Cr(VI) ions from aqueous solutions.   Manuscript profile -
Open Access Article
3 - Occupational Health Risk Assessment of Iranian Drilling Industry
Seyed Reza Shadizadeh Elahe AtaallahiDrilling industry provides a significant potential for occupational health risks. Thus, health-related hazards (chemical, physical, ergonomic and biological) must be recognized, evaluated and controlled in order to prevent occupational illnesses which come from exposure MoreDrilling industry provides a significant potential for occupational health risks. Thus, health-related hazards (chemical, physical, ergonomic and biological) must be recognized, evaluated and controlled in order to prevent occupational illnesses which come from exposure to them. For these, a good occupational health risk assessment needs to be applied. Risk assessment monitors risks and provides guidance for decision-making. This project identifies all the occupational health risks and estimated risk levels. At last, the risk numbers are assessed their significance by the use of occupational health risk assessment techniques to minimize the risks. The main goal is to gain a level of risk protection which is acceptable with a good model. Therefore, the Occupational health risk assessment worksheet illustrates health hazards into four categories of every tasks of drilling industry. The risk categorized in the five levels and the high risks of Iranian drilling industry are those in the category of c.   Manuscript profile -
Open Access Article
4 - Investigation of Cosenza Mutation in Patients with Deficiency of Glucose-6-Phosphate Dehydrogenase (G6PD) in North West of Iran
Omolbanin Javadi omoalbanin Javadi Habib Onsori habib onsoriGlucose-6-phosphate dehydrogenase (G6PD) is a greatly polymorphic enzyme encoded by human X-linked gene. G6PD deficit is the most public enzymopathy in human with about 400 million people affected globally. It is the main controlling enzyme in the hexose monophosphate s MoreGlucose-6-phosphate dehydrogenase (G6PD) is a greatly polymorphic enzyme encoded by human X-linked gene. G6PD deficit is the most public enzymopathy in human with about 400 million people affected globally. It is the main controlling enzyme in the hexose monophosphate shunt catalase the oxidation of glucose-6-phosphate to 6-phosphogluconolacton and the creation of reducing equals in the form of NADPH to meet the cellular redox formal and its absence origin hemolytic anemia - favism and newborn jaundice. Mutation in this enzyme cause three major types of unusual phenotype, including Mediterranean, Chatham and Cosenza. In this study, by Rapid Genomic DNA Extraction (RGDE) method, from 90 blood samples of unrelated male and female patients with genetic deficiency of G6PD, DNA was removed and next digestion by Eco81I enzymes, in order to research for Cosenza mutation, they were analyzed by means of PCR-RFLP. Sequencing methods were used. Of 90 patients, one patient had a Cosenza mutation frequency of 1.01%. Eighty-nine patients (98.99%) were not affected by the Cosenza-type mutation. Accordingly, Cosenza mutation is not regarded as the most common mutation in Iranian North-west population.   Manuscript profile -
Open Access Article
5 - Physicochemical and Organoleptic Properties of Lighvan Cheese Fortified with Protulaca Oleracea Seed Oil
Majid Keyvani Marzieh BolandiCheese has high nutritional value in human health although is naturally poor in essential fatty acids. Essential fatty acids revealed crucial roles in nutritional diet and have been suggested as disease prevention agent. Protulaca Oleracea (purslane) has considerable am MoreCheese has high nutritional value in human health although is naturally poor in essential fatty acids. Essential fatty acids revealed crucial roles in nutritional diet and have been suggested as disease prevention agent. Protulaca Oleracea (purslane) has considerable amounts of omega 3, 6 and 9 fatty acids as well as magnesium, potassium and vitamin C. The aim of this study is production and characterization of Lighvan cheese fortified with Protulaca Oleracea seed oil. Results indicated that increasing of Protulaca Oleracea seed oil caused significant increased omega 3,6 and 9 concentration in cheese (P<0.05). Protulaca Oleracea seed oil fortification showed no significant effects on physicochemical properties of Lighvan cheese (P>0.05). Lighvan cheese containing 2.5% Protulaca Oleracea (purslane) seed oil showed the highest sensory attributes. Â Â Â Manuscript profile -
Open Access Article
6 - Electrochemical Evaluation of Hydroxyapatite/ZrN Coated Magnesium Biodegradable Alloy in Ringer Solution as a Simulated Body Fluid
Seyed Rahim Kiahosseini Abdollah Afshar Majid Mojtahedzadeh Larijani Mardali YousefpourMagnesium alloys as biodegradable materials can be used in body as an implant materials but since they have poor corrosion resistance, it is required to decrease their corrosion rate by biocompatible coatings. In this study, hydroxyapatite (HA) coatings in the presence MoreMagnesium alloys as biodegradable materials can be used in body as an implant materials but since they have poor corrosion resistance, it is required to decrease their corrosion rate by biocompatible coatings. In this study, hydroxyapatite (HA) coatings in the presence of an intermediate layer of ZrN as a biocompatible material, deposited on AZ91 magnesium alloy by ion beam sputtering method at 300 °C temperature and at different times 180, 240, 300, 360 and 420 min. Then changes in corrosion resistance of samples in Ringer's solution as a solution similar to the human body was evaluated in two ways, potentiodynamic polarization and electrochemical impedance spectroscopy (EIS). To investigate the causes of the destruction of the samples, the surface of samples was studied by scanning electron microscopy (SEM). The results showed that because of porous coatings created, the corrosion potential of the samples was about +55mV higher than the uncoated substrate that by changing the deposition time, was not observed the significant change But with increasing deposition time to 360 min, corrosion current decreased which represents an increase of corrosion resistance of magnesium alloy in body solution. However, a further increase in deposition time to 420 min, due to increase thickness and stress in the layer, the corrosion resistance of the samples was reduced. The results of the EIS confirm the corrosion behavior of the polarization method, too.   Manuscript profile -
Open Access Article
7 - Assessment of Phytoextraction Potential of Fenugreek (Trigonellafoenum-graecum L.) to Remove Heavy Metals (Pb and Ni) from Contaminated Soil
Leela Kaur Kasturi Gadgil Satyawati SharmaThe objective of the present study was to evaluate the effect of metal mobilizing agents, ethelynediaminetetraacetic acid (EDTA) and salicylic acid (SA), on the accumulation and translocation of lead (Pb) and nickel (Ni) by fenugreek (Trigonellafoenum-graecumL.) plants MoreThe objective of the present study was to evaluate the effect of metal mobilizing agents, ethelynediaminetetraacetic acid (EDTA) and salicylic acid (SA), on the accumulation and translocation of lead (Pb) and nickel (Ni) by fenugreek (Trigonellafoenum-graecumL.) plants in contaminated soil. EDTA and SA were amended at 100 mM and 1.0 mM respectively. Pb and Ni content were estimated using ICP-OES. Plant samples were prepared for scanning electron microscope (SEM) analysis to investigate metals distribution in different tissues (root, stem and leaf) of plant. The results showed that EDTA increased Pb and Ni uptake as compared to SA. SEM analysis revealed that in the presence of EDTA, the deposition of Pb particles was predominantly in vascular tissues of the stem and leaf. Â Â Â Manuscript profile -
Open Access Article
8 - Determination of Carbamazepine in Biological Samples Using Ultrasound-Assisted Emulsification Micro-extraction and Gas Chromatography
Manoochehr Bahmaei Faezeh Khalilian Hossein Ali MashayekhiIn this study, simple and efficient ultrasound-assisted emulsification microextraction (USAEME) combined with gas chromatography-flame ionization detector (GC-FID) was developed for the preconcentration and determination of carbamazepine in biological samples. In this m MoreIn this study, simple and efficient ultrasound-assisted emulsification microextraction (USAEME) combined with gas chromatography-flame ionization detector (GC-FID) was developed for the preconcentration and determination of carbamazepine in biological samples. In this method, the fine droplets of 1-octanol were formed and dispersed in the sample with the help of ultrasonic waves, which accelerated the formation of the fine cloudy solution without using disperser solvents. Several factors influencing the extraction efficiency such as the nature and volume of organic solvent, extraction temperature, ionic strength and centrifugation time were investigated and optimized. The new method (USAEME) provided detection limits of 0.6 µg L-1 and 1.2 µg L-1 in urine and plasma samples, respectively. The calibration graphs were linear in the range of 2.5-500 µg L-1 and 5.0-500 µg L-1 in urine and plasma, respectively. This proposed method was successfully applied to the analysis of carbamazepine in biological samples.    Manuscript profile
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