Number 3 Volume 7

Open Access Article

1 - Tandem Synthesis and Optical Rotatory Dispersion Studies of a Novel Spiro Lactone (methyl 3-(benzo[d]thiazol-2-ylamino)-7,9-dimethyl-2,6,8,10-tetraoxo-1-oxa-7,9-diazaspiro[4.5]dec-3-ene-4-carboxylate)
Karim Ghafouri Samira Arab-salmanabadi Sajjad Sedaghat

Spiro compounds are of interest due to their interesting conformational features and their structural implications on biological systems. The asymmetric characteristic of the molecule due to the chiral spiro carbon is one of the important criteria of the biological acti More

Spiro compounds are of interest due to their interesting conformational features and their structural implications on biological systems. The asymmetric characteristic of the molecule due to the chiral spiro carbon is one of the important criteria of the biological activities. These structures are a widespread structural motif found as key elements of numerous drugs and designed medicinal agents in medicinal chemistry. Synthesis of these compounds always has been a challenging for organic chemists because it often requires synthetic design based on specific strategies. Due to the great importance of this class of compounds, chemists have a special attention to the synthesis of these compounds and a range of synthesis methods has been reported. In the current research a novel optically active spiro-lactone was synthesized via a tandem protocol ( michael addition, aldol reaction and γ-lactonization consecution) between benzo[d]thiazol-2-amine and dimethyl-acetylene dicarboxylate in the presence of 2, 4, 5, 6(1H, 3H)–pyrimidinetetrone (Alloxan). The synthesized compound has been successfully characterized by spectroscopy techniques. Also, evaluation of special optical rotatory on this synthesized spiro-lactone was investigated. Manuscript profile

Open Access Article

2 - SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 3-(2’-n-BUTYLBENZOFURAN-3’-YL)-5-ARYL-4, 5-DIHYDRO-1H-PYRAZOLES.
RAKESH P.N.ROSHAN D.M PUROHIT SANDIP K.MATARIYA

3-(2’-n-butylbenzofuran-3’-yl)-5-aryl-4, 5-dihydro-1H-pyrazoles (4a-4k) have been synthesized. The synthesized products have been assayed for their antimicrobial activity against Gram+ve, Gram-ve bacteria and fungi. All the synthesized products were assigned More

3-(2’-n-butylbenzofuran-3’-yl)-5-aryl-4, 5-dihydro-1H-pyrazoles (4a-4k) have been synthesized. The synthesized products have been assayed for their antimicrobial activity against Gram+ve, Gram-ve bacteria and fungi. All the synthesized products were assigned with IR, 1HNMR, Mass Spectra, TLC, and elemental analysis. Some of the products showed moderate activity, compare with known standard drugs. Manuscript profile

Open Access Article

3 - Soure orange skin as an Adsorption for Azo dyes removal from aqueous media
Parya Nasehi

In this study Soure orange skin as a good, natural and inexpensive adsorbent has been introduced and used for the removal of Erythrosine and red Carmoisine dyes from several water solutions successfully. The effect of various parameters such as pH, dye concentration, am More

In this study Soure orange skin as a good, natural and inexpensive adsorbent has been introduced and used for the removal of Erythrosine and red Carmoisine dyes from several water solutions successfully. The effect of various parameters such as pH, dye concentration, amount of adsorbent, contact time and temperature on removal processing was investigated. Adsorption isothermal data could be interpreted by the Langmuir and Freundlich, isotherm models. Manuscript profile

Open Access Article

4 - Synthesis of some isatin Schiff bases in microwave irradiation condition
Mohammad K Mohammadi

An efficient and mild methodology for rapid and efficient synthesis of isatin Schiff bases was described under microwave irradiation and solvent free condition.aromatic or heterocyclic Primary amines and isatin could be selectively reacted under microwave irradiation in More

An efficient and mild methodology for rapid and efficient synthesis of isatin Schiff bases was described under microwave irradiation and solvent free condition.aromatic or heterocyclic Primary amines and isatin could be selectively reacted under microwave irradiation into the corresponding isatin Schiff bases in high yields and short reaction time. Manuscript profile

Open Access Article

5 - Synthesis of new phenanthro imidazole derivatives in solvent free condition
Masih Golkari

phenanthro Imidazole derivatives were made synthesis the combinations of phenanthroquinone , Benzealdehyde derivatives in the presence of amines compounds. In all reactions, reactions were investigated under Microwave conditions. The structure of all compounds was studi More

phenanthro Imidazole derivatives were made synthesis the combinations of phenanthroquinone , Benzealdehyde derivatives in the presence of amines compounds. In all reactions, reactions were investigated under Microwave conditions. The structure of all compounds was studied by an IR Spectrums and 1HNMR Spectrums. Excellent yields, short reaction times, simplicity of operation and easy separation are several advantages of this technique. The results shown that the optimal conditions for the formation of phenanthro derivative of imidazole are at 70 ˚C, the power of 400 W and the time of two minutes. Manuscript profile

Open Access Article

6 - Synthesis of imidazole derivatives using nano-La0.5Pb0.5MnO3 perovskite-type oxide
Ali Javid

In this work,three component condensation of [9,10]-phenanthraquinone with benzaldehyde and ammonium acetate and nano Perovskites catalyst La0.5Pb0.5MnO3(NP-LPMO) was evaluated using a multicomponent reaction of phenanthroquinone,aromatic aldehydes and ammonium acetate More

In this work,three component condensation of [9,10]-phenanthraquinone with benzaldehyde and ammonium acetate and nano Perovskites catalyst La0.5Pb0.5MnO3(NP-LPMO) was evaluated using a multicomponent reaction of phenanthroquinone,aromatic aldehydes and ammonium acetate for preparation of imidazole derivatives. This reaction done under reflux conditions and compare with reaction with reaction in solvent-free reaction. Manuscript profile

XML

List of Articles