-
حرية الوصول المقاله
1 - Phytochemical investigation and isolation of new compounds from the stems of <i>Tinospora cordifolia</i> Miers
Shahnaj Sultana Mohammed Ali Mohammad JameelTinospora cordifolia (Willd.) Miers, (Menispermaceae), a glabrous, deciduous and trailing plant found in tropical India, China, Sri Lanka, Bangladesh and Myanmar. It is used to treat anemia, debility, diabetes, diarrhea, dysentery, dyspepsia, fevers, jaundice, rheumatis أکثرTinospora cordifolia (Willd.) Miers, (Menispermaceae), a glabrous, deciduous and trailing plant found in tropical India, China, Sri Lanka, Bangladesh and Myanmar. It is used to treat anemia, debility, diabetes, diarrhea, dysentery, dyspepsia, fevers, jaundice, rheumatism, urinary and skin diseases and snake bites. Its air-dried stem powder was exhaustively extracted with methanol. The concentrated methanolic extract was adsorbed on silica gel (60-120 mesh) for the preparation of a slurry. The dried slurry was chromatographed over silica gel column packed in petroleum ether. The column was eluted with petroleum ether, chloroform and methanol successively in order of increasing polarity to isolate a variety of new chemical constituents characterized as trans-cinnamoyl 2-n-hexanyl-7-methoxynaphthyl amide (2), trans-cinnamoyl 2-n- pentanyl- 6,7- dimethoxynaphthyl amide (3), trans-cinnamoyl 2-n-octanyl-7-methoxynaphthyl amide (4), β-D-arabinosyl-O-geranilan-10′-oate (5), 4,5,7-trimethoxy-2-naphthol-2-O-α-L- arabinofuranosyl-(2′→1′′)-O-α-L-arabinopyranosyl-2′′-O-pentane (6), 5,7-dimethoxy-2-naphthol-2-O-α-L-arabinopyranosyl-(2′→1′′)-α-L- arabinopyranosyl-2′′-O-decane (7) and 5-hydroxy-4''-methoxy-7- flavanoxy- (7→7'''')- β-O-labdan-1-en-3''''α,19''''-olide-18''''-oic acid (tinolabdenyl flavanone) (8) along with cetyl alcohol (1). The structures of all the isolated phytoconstituents have been established on the basis of spectral data analysis and chemical reactions. تفاصيل المقالة -
حرية الوصول المقاله
2 - Understanding the phytochemical constitution, antioxidant potential and spectral characteristics of aqueous extracts of the chosen leafy vegetables from south India
Sobha Kota Pradeep Dumpala Hariseetharam Prasad Dachepalli Anantha Ratna KumariThe phytochemical composition, total phenolic and ascorbic acid contents of the aqueous extracts of six south Indian leafy vegetables viz. Amaranthus viridis L, Hibiscus cannabinus L, Spinacea oleracea L, Mentha spicata L, Murraya koenigii L and Coriandrum sativum L wer أکثرThe phytochemical composition, total phenolic and ascorbic acid contents of the aqueous extracts of six south Indian leafy vegetables viz. Amaranthus viridis L, Hibiscus cannabinus L, Spinacea oleracea L, Mentha spicata L, Murraya koenigii L and Coriandrum sativum L were tested, characterized and the antioxidant potential evaluated. Also, aqueous leaf extracts of A. viridis and H. cannabinus were demonstrated for their ability to form silver nanoparticles. All the aqueous extracts demonstrated the presence of flavonoids, saponins, tannins (except M. koenigii) and terpenoids (except S. oleracea) while phlobatannins (only in M. spicata), steroids, cardiac glycosides, alkaloids and proteins were absent in all the leaves tested. Carbohydrates were found only in the aqueous extract of H. cannabinus. The total phenolic content was the order of 0.9, 0.2, 1.8, 0.8 and 2.1 mgGAE/g of the leaves for A. viridis, H. cannabinus, M. spicata, M. koenigii and C. sativum respectively while S. oleracea did not respond to total phenolic content assay by FC method. Ascorbic acid, present in all the leafy vegetables with the lowest value of 0.3 mg/g in M. spicata and highest value of 1.9 mg/g in C. sativum. A highly significant DPPH radical scavenging activity was found in H. cannabinus (82.76%) followed by M. spicata (78.08%) and C. sativum (69.76%) at an extract concentration of 31.25 mg/ml while A. viridis, S. oleracea and M. koenigii showed 72.95%, 58.27% and 75.38% respectively at a concentration of 50 mg/ml. FT-IR spectral characterization of the extracts and the synthesized silver nanoparticles (Ag NPs) indicated the presence of N-H amines, O-H stretch, C-H out of plane bending vibrations, C=C stretching of alkenes, C=O stretch of amide and C≡C stretch of alkynes. The leafy vegetables can be used for the synthesis of lead compounds which will cure diseases. تفاصيل المقالة -
حرية الوصول المقاله
3 - Chemical constituents and antimicrobial activities of some isolated compounds from the Cameroonian species of <i>Senna alata</i> (<i>Cassia alata</i> L. Roxb synonym, The plant list 2013). (Leguminosae)
Simplice Chimi Fotso Alain Tcho Tadjong Willifred Dongmo Tekapi Tsopgni Bruno Lenta Celine Nkenfou Jean Duplex Wansi Flavien Aristide A. TozeOne fatty acid (1), one monoglycol ester (2), three diterpenes (3-5), four steroids (6-9), four triterpenes (10-13), three flavonoids (14-16), three anthraquinones (17-19) and one benzoquinone (20), were isolated from the methanolic extract of the leaves and trunk of Se أکثرOne fatty acid (1), one monoglycol ester (2), three diterpenes (3-5), four steroids (6-9), four triterpenes (10-13), three flavonoids (14-16), three anthraquinones (17-19) and one benzoquinone (20), were isolated from the methanolic extract of the leaves and trunk of Senna alata. These compounds were obtained by extensive silica gel chromatography and their structures elucidated by 1D and 2D nuclear magnetic resonance (NMR) as well as comparison with literature data. Compounds (2-4) have been reported for the first time from this species. Some isolated compounds and methanolic crude extract of leaves and trunk were screened in vitro for their antimicrobial activities. Kaempferol (16) exhibited strong activity against all the tested strains, with MIC values varying from 15.5 to 31.2 µg/mL, emodin (18) was active with a strong activity (7.8 µg/mL) exhibited on Pseudomonas aeruginosa. The trunk crude extract showed a strong activity with MIC values varying from 15.6 to 62.5 µg/mL. تفاصيل المقالة -
حرية الوصول المقاله
4 - Phytochemistry, traditional uses, and pharmacology of the genus <i>Ekebergia</i> (Meliaceae): A review
Guy Paulin Mouthe Kemayou Sorelle Fotsing Kache Liliane Clotilde Dzouemo Gervais M. Happi Simeon Fogue Kouam Jean Claude TchouankeuEkebergia (Meliaceae) is a genus of flowering shrubs and trees widely distributed in the African continent. It is represented by four species namely E. capensis Sparrm, E. benguelensis Welw. ex C.DC, E. pterophylla (C.DC.) Hofmeyr and E. pumila I.M.Johnst. The informati أکثرEkebergia (Meliaceae) is a genus of flowering shrubs and trees widely distributed in the African continent. It is represented by four species namely E. capensis Sparrm, E. benguelensis Welw. ex C.DC, E. pterophylla (C.DC.) Hofmeyr and E. pumila I.M.Johnst. The information for this review has been collected via a survey performed through several online libraries including the Plantlist, Jstor, Scifinder, PubMed, Google Scholar, Web of Science and Dictionary of Natural Products. So far, about 69 distinct compounds have been isolated during the previous phytochemical studies of Ekebergia genus plants. These compounds belong to diverse classes of metabolites such as limonoids, triterpenoids, coumarins, steroids, alkaloids, stilbenes and phenolic compounds. Some of these isolates displayed various bioactivities including antiplasmodial, antimicrobial, antiproliferative or uterotonic activities. This review covers the traditional uses, the phytochemical and pharmacological investigations of the genus Ekebergia over the last four decades (1980 to 2020). تفاصيل المقالة -
حرية الوصول المقاله
5 - تاثیر ضدباکتریایی اسانس مریم گلی بر علیه 4 باکتری بیماری زای انسانی و شناسایی ترکیبات تشکیل دهنده اسانس
اشرف کریمی نیک وحید دریجانیدر بسیاری از نقاط دنیا استفاده از طب گیاهی برای درمان بسیاری از بیماری های عفونی سابقه دیرینه سنتی دارد. به دلیل اثرات جانبی و مقاومتی که میکروارگانیسم های بیماریزا در مقابل آنتی بیوتیک ها ایجاد می کنند، اخیراً توجه زیادی به استخراج ترکیبات فعال بیولوژیکی از گونه های گی أکثردر بسیاری از نقاط دنیا استفاده از طب گیاهی برای درمان بسیاری از بیماری های عفونی سابقه دیرینه سنتی دارد. به دلیل اثرات جانبی و مقاومتی که میکروارگانیسم های بیماریزا در مقابل آنتی بیوتیک ها ایجاد می کنند، اخیراً توجه زیادی به استخراج ترکیبات فعال بیولوژیکی از گونه های گیاهی مورد استفاده در طب گیاهی شده است. هدف این مطالعه بررسی فعالیت ضد باکتریایی اسانس گیاه مریم گلی بر روی 4 سویه استاندارد باکتری و شناسایی ترکیبات شیمیایی تشکیل دهنده آن بوده است. اسانس گیاه با روش تقطیر آبی توسط دستگاه کلونجر استخراج شد و از طریق گاز کروماتوگرافی- اسپکتروسکوپی جرمی (طیف سنج جرمی) تجزیه و تحلیل شد. ۱۰ ترکیب شناسایی شدند که لینالول (8/54 درصد) و اسکلارول (3/27 درصد) به عنوان ترکیبات غالب شناسایی گردیدند. فعالیت ضد میکروبی اسانس گیاه در برابر سویه های استاندارد باسیلوس سرئوس، استافیلوکوکوس اورئوس، اشریشیاکلای و سالمونلاانتریکا ارزیابی شد. نتایج نشان داد که همه باکتری های مورد مطالعه نسبت به اسانس حساس بودند. حداقل غلظت کشندگی اسانس نسبت به باکتری استافیلوکوکوس اورئوس، باسیلوس سرئوس، اشریشیاکلای و سالمونلاانتریکا به ترتیب 15/0، 15/0، 38/0 و 77/0 درصد بودند. نتایج به دست آمده به کارگیری اسانس گیاه بومی مریم گلی مورد استفاده در طب سنتی را برای درمان عفونت های میکروبی و یا به عنوان نگهدارنده مواد غذایی تایید و پیشنهاد می نماید. تفاصيل المقالة -
حرية الوصول المقاله
6 - Pharmacognostic studies of Spermadictyon suaveolens Roxb. and their traditional ethnomedicinal utilization: A review
مازنا اروج نصیر شادBackground & Aim: The current study was performed to evaluate the ethnobotanical uses, chemical constituents of Spermadictyon suaveolens Roxb. and their pharmacological activities through literature search. Owing to its traditional medicinal uses, its preliminary ph أکثرBackground & Aim: The current study was performed to evaluate the ethnobotanical uses, chemical constituents of Spermadictyon suaveolens Roxb. and their pharmacological activities through literature search. Owing to its traditional medicinal uses, its preliminary phyto-evaluation has resulted in various bioactive compounds, which have been shown to have antimicrobial and antiviral potential.Experimental: We conducted a survey in diverse databases (such as Google scholar, Scopus, and Web of Science, etc.) and professional websites with a key word related to our study. Firstly, we evaluated the traditional utilization of Spermadictyon suaveolens Roxb. and then the pharmacological studies.Results: Spermadictyon suaveolens are traditionally utilized by tribes to treat bone pain, wound healing, diabetes, snake bites, scorpion stings, viral infection, and for making gunpowder charcoal. The leaves, flowers, and stems of Spermadictyon suaveolens have been investigated for various chemical compounds with pharmacological activities, such as antifungal, antimicrobial, antimalarial, antioxidant, anticancer, anti-inflammatory, anti-diuretic, and insecticidal activities. The root and bark are not well explored for chemical constituents and pharmacological activities.Recommended applications/industries: Spermadictyon suaveolens Roxb need to be subjected to scientific verification based on their traditional utilization, which may lead to a better and effective alternative phytoconstituents for the management of various diseases. تفاصيل المقالة -
حرية الوصول المقاله
7 - Pharmacognostic investigation of Astragalus graveolens leaf and their traditional ethnomedicinal utilization
خورشید رحمان غلام مجتبی شاه محمد اجمل شاه محمد فیاز جان آلام سامیا عباسی مریم شهید اقرا بی بیBackground & Aim: The current study was performed to evaluate the ethnobotanical uses, chemical constituents of Astragalus graveolensBuch. Leaves and their pharmacological activities through literature search. The preliminary phyto-evaluation of this plant has produ أکثرBackground & Aim: The current study was performed to evaluate the ethnobotanical uses, chemical constituents of Astragalus graveolensBuch. Leaves and their pharmacological activities through literature search. The preliminary phyto-evaluation of this plant has produced a number of bioactive chemicals, some of which have been proven to have antibacterial and cytotoxic potential as a result of its traditional therapeutic applications.Experimental: We conducted a survey in diverse databases (such as Google scholar, Scopus, and Web of Science, etc.) and professional websites with a key word related to our study. Firstly, we evaluated the traditional utilization of Astragalus graveolensBuch. and then the pharmacological studies.Results: Astragalus graveolens has a number of health advantages, including the ability to treat toothaches, strengthen tooth roots, nourish and treat chest infections, kidney, stomach and toothaches. Renal issues, burns, hypertension, and demulcent. Back pain, kidney pain, tooth pain, diabetes, tooth pain, bone pain, bone pain in the bone and tooth pain. They used in food, as a sweetener, a tonic, a headache and stomach pain reliever and to speed up the healing of deep wounds that are infected. The leaves of Astragalus graveolens have been investigated for various chemical compounds with pharmacological activities, such as antifungal, antimicrobial, antimalarial, antioxidant, anticancer, anti-inflammatory, anti-diuretic, analgesic and insecticidal activities. The leaves are not well explored for chemical constituents and pharmacological activities.Recommended applications/industries: Astragalus graveolens Buch. need to be subjected to scientific verification based on their traditional utilization, which may lead to a better and effective alternative phytoconstituents for the management of various diseases. تفاصيل المقالة
سند
Sanad is a platform for managing Azad University publications
الروابط
المراكز ذات الصلة
دعامة
الصفحات الرسمية
حقوق هذا الموقع الإلكتروني مملوكة لنظام SANAD Press Management. © 1442-1446