• فهرس المقالات Phenylpropanolamine (PPA) Drug

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        1 - Synthesis of PbS Functionalized with gelatin as a Fluorescence-Enhanced Sensor for determination of Phenylpropanolamine (PPA) drug in blood and urine samples
        Shirin Bouroumand Farzaneh Marahel Fereydoon Khazali
        Sensor synthesis synthesized PbS functionalized with gelatin quantum dots have been considered as novel drugs sensors due to their ultrafine size, photo-stability and excellent fluorescent properties. In this study, a facile method was developed for the preparation of f أکثر
        Sensor synthesis synthesized PbS functionalized with gelatin quantum dots have been considered as novel drugs sensors due to their ultrafine size, photo-stability and excellent fluorescent properties. In this study, a facile method was developed for the preparation of fluorescent water-soluble PbS quantum dots with gelatin sensor. The fluorescence of the PbS quantum dots sensor functionalized with gelatin synthesis is selectively and sensitively enhanced by addition of the Phenylpropanolamine (PPA) drug-induced aggregation of sensor PbS with gelatin. This finding was further used to design a fluorometric method for the determination of (PPA) drug, The reaction is followed fluoremetrically by measuring the absorbance at 335 nm. 2.5×10-2 molL-1 PbS with gelatin sensor, calibration graph in the rang of 0.05 - 10.0 µg L-1 (PPA) drug. The absorbance is linear from 0.05 up to 100.0 µg L−1 in aqueous solution with repeatability (RSD) of 3.5% at a concentration of 10.0 µg L−1 and a detection limit of 2.2 µg L−1 by the fixed-time method of 60 sec. The relative standard deviation for 10.0 µg L-1 (PPA) drug is %95. The applicability of the method was demonstrated by the determination of the (PPA) drug in urine and blood samples تفاصيل المقالة
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        2 - Designed a Fluorescent Method by Using PbS with Gelatin via Quantum Dots for the Determination of Phenylpropanolamine Drug in Human Fluid Samples
        Shirin Bouroumand Farzaneh Marahel Fereydoon Khazali
        Fluorescent chemical sensors to detect drugs, by increasing fluorescence emission and absorption or by shutting down, because they are non-destructive, the ability to show decomposed concentrations, fast response, high accuracy have been considered and used. In this res أکثر
        Fluorescent chemical sensors to detect drugs, by increasing fluorescence emission and absorption or by shutting down, because they are non-destructive, the ability to show decomposed concentrations, fast response, high accuracy have been considered and used. In this research, a chemical sensor was synthesized PbS functionalized with gelatin quantum dots for Phenylpropanolamine (PPA) drug. The calibration curve was linear in the range of (0.05 to 10.0 µgL−1). The standard deviation of less than (2.0 %), and detection limits (3S/m) of the method (0.05 µgL−1) in time 60 s, 335 nm were obtained for sensor level response PbS Quantum Dot–Gelatin nanocomposites sensor with (99 %), confidence evaluated. The observed outcomes confirmed the suitability recovery and a very low detection limit for measuring the Phenylpropanolamine drug. The method fluorometric introduced to measure Phenylpropanolamine in real samples such as urine and blood was used and can be used for other drugs and hospital samples. The chemical PbS Quantum Dot–Gelatin nanocomposites sensor made it possible as an excellent sensor with good reproducibility. تفاصيل المقالة