• فهرس المقالات Nonlinear system of Differential Equation

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        1 - Optimal Control of Hand, Foot and Mouth Disease Model using Variational Iteration Method
        Devipriya Ganeshan L. Jane Darne
        In this paper, the optimal control of transmission dynamics of hand, foot and mouth disease (HFMD), formulated by a compartmental deterministic SEIPR (Susceptible-Incubation (Exposed)- Infected - Post infection virus shedding - Recovered) model with vaccination and trea أکثر
        In this paper, the optimal control of transmission dynamics of hand, foot and mouth disease (HFMD), formulated by a compartmental deterministic SEIPR (Susceptible-Incubation (Exposed)- Infected - Post infection virus shedding - Recovered) model with vaccination and treatment as control parameters is considered. The objective function is based on the combination of minimizing the number of infected individuals and the cost involved in the interventions of vaccination given to the susceptible population and treatment given to the infected population. The existence for the optimal control pair is proved and the characterization of the optimal control pair is obtained by applying the Pontryagin's maximum principle. The variational iteration method is adopted to solve the non-linear Hamilton equations derived from the Pontryagin's maximum principle theory. These equations constitute a two-point boundary value problem. By considering the correction functionals of the Hamilton equations, the Lagrange multipliers are easily identified and practical iteration formulas are derived. An algorithm is developed, based on this formulas, to determine iteratively the solutions of the Hamilton equations with a desired accuracy. With the aid of solutions obtained, the optimal control law can be easily deduced. The results were analyzed and interpreted graphically using Maple. تفاصيل المقالة
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        2 - Analytical Solution of the Effect of Awareness Program by Media on the Spread of an Infectious Disease by Homotopy Perturbation Method
        Devipriya Ganeshan
        In this paper, the nonlinear dynamical system modeling the effect of awareness program by media on spread of infectious disease is considered. The model is mathematically formulated by the deterministic compartmental model consisting of susceptible population, infected أکثر
        In this paper, the nonlinear dynamical system modeling the effect of awareness program by media on spread of infectious disease is considered. The model is mathematically formulated by the deterministic compartmental model consisting of susceptible population, infected population, aware population and cumulative density of awareness spread by the media. Homotopy perturbation method is used to obtain the approximate solution of the governing nonlinear differential equation, which consists in determining the series solution convergent to the exact solution or enabling to built the approximate solution of the problem. Numerical solutions are obtained and the results are discussed graphically using Maple. The method allows to determine the solution in form of the continuous function, and shows the significance of awareness program driven by media in spread of an infectious disease, but due to immigration, the disease may remain endemic . The simulation analysis of the model with different parameter values confirms the analytical results. تفاصيل المقالة