Anti-inflammatory activity of leaf extract of Solanum anomalum

Subject Areas : Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)

جود اکوکون ¹ , کوفره دیویز ² , لوییس آمازو ³ , امام یوموه ⁴

1 - Department of pharmacology and toxicology, Faculty of pharmacy, University of Uyo, Uyo, Nigeria
2 - Department of Physiology, Faculty of Basic Medical Sciences, University of Uyo, Uyo, Nigeria
3 - Department of Pharmacology and Therapeutics, College of Medicine, Evans Enwerem University, Orlu Campus, Imo State
4 - Department of pharmacology and toxicology, Faculty of pharmacy, University of Uyo, Uyo, Nigeria

Received: 2016-02-19 Accepted : 2016-04-15 Published : 2017-01-01

Keywords: Solanum anomalum, Antiinflammatory, Oedema,

Abstract :

Background & Aim: Solanum anomalum Thonn. ex Schumach. (familySolanaceae) is a shrub growing up to 2 metres tall. The edible fruits are gathered from the wild and consumed locally and the leaves are used locally in the treatment of various diseases. Evaluation of anti-inflammatory activity of leaf extract of Solanum anomalum was carried out to ascertain its uses in traditional medicine. Experimental: The crude leaf extract (70 – 210 mg/kg) of Solanum anomalum was investigated for anti-inflammatory activity using various experimental models; carragenin, egg albumin and xylene induced oedema. Results: The extract (70 -210 mg/kg) caused a significant (p Recommended applications/industries: The plant, Breynia nivosa, possesses antiinflammatory property which can be exploited in the treatment of inflammatory diseases.

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