Evaluation of the immunological changes in the use of Sumac herb powder (Rhuscoriaria) compared with Levamisole in dogs
Subject Areas : Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)علی وحید دستجردی 1 , سام ترکان 2 , محسن جعفریان 3
1 - گروه علوم درمانگاهی، دانشکده دامپزشکی، واحد شهرکرد، دانشگاه آزاد اسلامی، شهرکرد، ایران؛
2 - گروه علوم درمانگاهی، دانشکده دامپزشکی، واحد شهرکرد، دانشگاه آزاد اسلامی، شهرکرد، ایران؛
3 - گروه علوم درمانگاهی، دانشکده دامپزشکی، واحد شهرکرد، دانشگاه آزاد اسلامی، شهرکرد، ایران؛
Keywords: Dog, sumac, Levamisole, Immunology,
Abstract :
Background & Aim: One of the major problems of modern medicine is the increasing consumption of synthetic drugs and frequent use of them will result in side effects. Considering this issue, patients should be mainly motivated to use pharmaceutical plants. Regarding the positive effects of sumac on the immune system, in the present study, we made a decision to compare sumac with levamisole as a chemical immune system stimulant compound. Experimental: In this research, 8 native breed of dogs were studied for ten days. The dogs were divided into four groups of two including a control group, a group consuming levamisole, a group consuming the amount of 10 mg per kg sumac, and a group receiving 5 mg per kg sumac. Then, blood samples were taken and the relevant tests were performed after completing the period of intaking the prescribed amount of powders of sumac plant and oral levamisole. Results: According to present results, significant differences were observed between treatment and control groups in terms of some factors including phagocytosis, multiplicity of phagocytosis mass and IGM whereas there was no significant difference in other factors (p < 0.05). It was revealed that sumac plant same as levamisole can increase immunity and phagocytosis in dogs. Recommended applications/ industries: In present study, considering the significant positive effects of sumac on some immunological parameters, this herb is recommended to be prescribed in the food.
Abuk, K.A., Andrew, H.L., Shiv, P. 2015. cellular and molecular immunology.8th ed. Pp 1-10.
Ahmadian Atari, M.M., Amin, G.H., Fazeli, M.R. and Jamalifar, H. 2007. Survey of the antibacterial activity of sumac fruit. Medical Plants Periodical, 1:1-9.
Allen, D.G., Pringle, J.K., Smith, D.A., Pasloske, K. and Day, K. 1998. Handbook of veterinary drugs, Lippincott-Raven Publishers, Pp.134.
Amin, G.R. 1991. Popular medicinal plants of Iran. Iranian Research Institute of Medicinal Plants Tehran, 3:1-8.
Atiyabe, N. 2005. Veterinary clinical pathology and laboratory methods. Tehran University Puplication, Tehran, Pp. 20-30.
Capcarova, M., Slamecka, J., Abbas, K., Kolesarova, A.,Kalafova, A., Valent, M., Filipejova, T., Chrastinova, L., Ondruska, L. and Massanyi, P. 2012. Effects of dietary inclusion of Rhus coriaria on internal milieu of rabbits. Journal of Animal Physiology and Animal Nutrition, 96(3): 459-465.
Dehkordi, H.S., Dehkordi, M.J., Chaleshtori, M.R., Khamesipour, F., Katsande, S. 2015. Effect of alcohol extract of Zataria multiflora (Boiss), Satureja bachtiarica (Bunge) and Zaravschanica membranacea (Boiss) on immuno-hematologic factors in rats. Tropical Journal of Pharmaceutical Research, 14(11):1999-2004.
Einstein, R., Jones, R., Knifton, A. and Starmer, G. 1994. Principles of veterinary therapeutics, Longman Scientific and Technical, Pp. 570.
Fazeli, M.R., Amin, G., Attari, M.M.A., Ashtiani, H., Jamalifar, H. and Samadi, N. 2007. Antimicrobial activities of Iraniansumacandavishan-e shirazi (Zataria multiflora) against some food-borne bacteria. Food Control, 18(6): 646-649.
Ghamarian, A.R., Mirzaie, E.H. 2008. Animal drugs of iran.Tehran. Noorbakhsh Puplication, Pp. 51.
Mozafarrian, V. 1998. Dictionary of the names of Iranian plants. Farhange Moaser, Tehran, Pp. 29-31.
Shahbazi, P. Maleknia, N. 2005. General Biochemistry. Tehran University Press, Tehran. p 502.
Sharbati alishah, A., Daneshyar, M., Aghazadeh, A.M. 2012. Effects of different levels of sumac seed on growth, blood parameters and Carcass characteristics of broilers under heat stress. Journal of Animal Science. 97:49-51.
Taha, S.O. 2013. In Vivo Antimicrobial Activity of Ethanol Extract of Sumac (Rhus coriaria) on Klebsiella pneumoniae. British Journal of Pharmacology and Toxicology, 4(1): 1-4.
Tohouri,S.H. 2010.Encyclopedia of medical plants. Qom. padideh danesh puplication, Pp: 267-269.
Zargari, A. 1997. Iranian medicinal plants. Tehran University Publications, Tehran, 1: 558-565.
Zolfaghari, B., GHanadi, A., Moshkelgosha, V., Monirifard, R., Deghan, M. and Nilfroshzadeh, M.A. 2011. Evaluation and clinical assessment of A combination herbal remedy In the treatment of recurrent labialis herpes. Urmia Medical Journal, 22(4): 315-321.