Green synthesis of imidazole derivatives using multicomponet reactions of ninhydrins

Subject Areas : Iranian Journal of Organic Chemistry

Received: 2023-10-01 Accepted : 2023-10-20 Published : 2023-10-30

Keywords: Ninhydrin, Primary amine, Arylisocyanates, Multi component reaction,

Abstract :

An efficient synthesis of functionalized imidazols via a one-pot reaction between ninhydrin, primary alkylamines, and arylisocyanates, in water at room temperature is described.

References:

Mechanistic Investigation of the [1+4] Cycloaddition Reaction Between Alkyl Isocyanides and 3-benzylidene-2,4-pentanedione: A Theoretical Study
Print Date : 2020-07-17
Synthesis and characterization of PTS and PDATS: Two maiden functionalized energetic polymers having tetrazole and triazine rings
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BF3 catalyzed hydroarylation reactions of arylsubstituted alkynes with different electron rich arenes
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Synthesis of some 3-indolyl heterocycles and evaluation of its antimicrobial activity
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1,3,4-Thiadiazole rings as π-spacers in triphenylamine based dyes: A density functional theory study of reactivity, UV/Visible spectra, structural and optical properties
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Graphical Abstract
Print Date : 2014-05-01

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Green synthesis of imidazole derivatives using multicomponet reactions of ninhydrins