A novel three-component reactions of 4-hydroxycumarine for the synthesis of oxazine derivatives in water
Subject Areas : Iranian Journal of Organic Chemistry
Seyyed Jalal Shams Najafi
1
(
)
Maryam Ghazvini
2
(
)
Atefeh Navabi
3
(
)
Keywords: 1, Three-component reaction, isocyanide, 2-hydroxyacetophenone, 3-benzoxazine, Isoquinoline,
Abstract :
A simple and proficient method for the synthesis of 1,3-benzoxazine derivatives via three-component reaction of isocyanide and isoquinoline with 2-naphthol in water in the presence of piperidine at 70oC is reported.