Green synthesis of functionalized oxaphosphole-1,2,4-triazoles: Investigation of biological Activity

Haerizadeh, Narjes; Koohi, Maryam

Manuscript ID : 697963 Visit : 97 Page: 3379 - 3384

Article Type: Original Research

Green synthesis of functionalized oxaphosphole-1,2,4-triazoles: Investigation of biological Activity

Subject Areas : Iranian Journal of Organic Chemistry

Narjes Haerizadeh ¹ , Maryam Koohi ²

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Received: 2022-12-21 Accepted : 2022-12-21 Published : 2022-08-01

Keywords: Ammonium thiocyanate, Esterification, N-formylmorpholine, Acid chlorides, 3-Hydroxy-2-butanone,

Abstract :

The reaction of activated acetylenic compounds with triphenylphosphine (Ph3P) in the presence of isatins or itsderivatives and hydrazonoyl chlorides led to oxaphosphole-1,2,4-triazole derivatives in good yields. Also, antioxidant property of some prepared compounds was investigated using diphenyl-picrylhydrazine (DPPH) radical trapping experiment.

References:

Mechanistic Investigation of the [1+4] Cycloaddition Reaction Between Alkyl Isocyanides and 3-benzylidene-2,4-pentanedione: A Theoretical Study
Print Date : 2020-07-17
Synthesis and characterization of PTS and PDATS: Two maiden functionalized energetic polymers having tetrazole and triazine rings
Print Date : 2014-02-01
BF3 catalyzed hydroarylation reactions of arylsubstituted alkynes with different electron rich arenes
Print Date : 2014-11-01
Synthesis of some 3-indolyl heterocycles and evaluation of its antimicrobial activity
Print Date : 2016-08-01
1,3,4-Thiadiazole rings as π-spacers in triphenylamine based dyes: A density functional theory study of reactivity, UV/Visible spectra, structural and optical properties
Print Date : 2015-11-01
Graphical Abstract
Print Date : 2014-05-01

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Green synthesis of functionalized oxaphosphole-1,2,4-triazoles: Investigation of biological Activity