1,3-Dipolar Cycloaddition Reaction of Dibenzalaceton with Non-stabilized Azomethinylides: Synthesis of New Spirooxindolo(pyrrolizidines/ pyrrolidines)
Subject Areas : International Journal of Bio-Inorganic Hybrid Nanomaterials
Keywords: Proline, 1, 3-Dipolar cycloaddition, Azomethinylides, Spiro-oxindolo(pyrrolizidines/ pyrrolidines), isatin, Sarcosine,
Abstract :
1,3-dipolar cycloaddition reaction of 1 mol or 2 mol of dibenzalaceton with 1 mol of non-stabilized azomethinylides generated in situ by decarboxylative condensation of isatin and proline or sarcosine give the novel new spiro-oxindolo(pyrrolizidines/ pyrrolidines) instead of bis-spirooxindolo( pyrrolizidines/ pyrrolidines).