بررسی جامع زیست حسگرهای نوری
محورهای موضوعی : شیمی و مهندسی شیمی کلیه گرایش ها
نوشین داداش زاده
1
*
,
ناصر مصلحی میلانی
2
1 - Department of physics, Faculty of physics,Hadishahr Branch, Islamic Azad University,jolfa, Iran.
2 - گروه فیزیک، واحد اهر، دانشگاه آزاد اسلامی، اهر، ایران
کلید واژه: انواع زیست حسگرهای نوری, کاربرد زیست حسگرهای نوری, تشدید پلاسمون سطحی,
چکیده مقاله :
حسگرها، عملکرد ارزشمندی را در مطالعات زیست محیطی، کشاورزی، بازرسی و ایمنی مواد غذایی، پاسخ سریع و مقرون به صرفه در بیوتکنولوژی، تشخیص بیماری و خدمات پزشکی و ... از خود نشان داده‌اند. از میان بسیاری از دسته‌های حسگرها، حسگرهای زیستی نوری به دلیل اندازه‌گیری‌های انتخابی، سریع و بسیار حساس خود، دارای مزایای اضافی مانند استحکام، قابلیت اطمینان و پتانسیل ادغام بر روی تراشه هستند. در مورد حسگرهای زیستی نوری، آنالیت با استفاده از نور با تکنیک‌های مبتنی بر برچسب یا بدون برچسب شناسایی می‌شود. در این مقاله برخی از پیشرفت‌های قابل توجه در دهه گذشته در زمینه حسگرهای زیستی نوری با تاکید بر رویکردهای ساخت آنها و حوزه‌های کاربردی رو به رشد، بررسی شده است. همراه با برخی از مقاله‌های با دقت انتخاب شده در مورد پیشرفت‌های جدید در حسگرهای زیستی نوری مروری کوتاه از حسگرهای زیستی نوری از زمان پیشرفت نیز ارائه شده است. همچنین چالش‌ها و آینده فناوری‌های حسگر زیستی نوری در حال ظهور در دهه جاری ارائه شده است.
چکیده انگلیسی:
Sensors have shown valuable performance in environmental studies, agriculture, inspection and food safety, quick and cost-effective response in biotechnology, disease diagnosis and medical services, etc. Among the many categories of sensors, optical biosensors have additional advantages such as robustness, reliability, and the potential for on-chip integration due to their selective, rapid, and highly sensitive measurements. Biosensors are analytical tools used for the detection of specific analytes such as cholesterol, urea, etc. that have biomolecules such as nucleic acids, proteins, carbohydrates as key elements for the detection of these analytes along with transducers and data analysis and visualization tools. In the case of optical biosensors, the analyte is detected using light with either label-based or label-free techniques. In this paper, some of the significant advances in the field of optical biosensors in the past decade are reviewed, with an emphasis on their fabrication approaches and growing application areas. Along with some carefully selected articles on new developments in optical biosensors in the past decade, a brief overview of optical biosensors since their development is also provided. Another focus of the current review is the classification of biosensors, typical structures along with emerging advances in optical biosensing that are likely to dominate the current decade. Also, the challenges and future of emerging optical biosensor technologies in the current decade are presented.
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