Electro spraying is similar to electro spinning but when the viscosity of polymeric solution is not high enough to form nanofibers, electro spraying can be used to make nanoparticles .In this study Chitosan / gum tragacanth blend nanoparticles were produced using electro - spinning / sparying device and the chitosan and gum tragacanth concretions on properties of resulting nanoparticles was investigated . The morphology of electro - sprayed chitosan / gum tragacanth blend were characterized using scanning electron microscope (SEM) . The results showed that electro spraying technique is capable of forming gum tragacanth - chitosan blend nanoparticles with an average size of 200 to 300 nm . The miscibility of blend was determined using Fourier transform infrared spectrometer (FTIR) . Antibacterial property of samples was also investigated. Wettability results of gum tragacanth - chitosan nanoparticles ( Contact - angle measurements ) indicate hydrophilic property of nanoparticles which is needed for biocompatible applications.` تفاصيل المقالة