Cellular structures are broadly used because of their exclusive properties in tissue engineering. This research proposes a new method, both in design and manufacturing, to engineer their mechanical properties considering gradient material and geometrical features and evaluate the possibility of using created structures as bone implants. Schwarz-primitive surface has been utilized to design cellular structures with different porosities and unit cell sizes. A total of 18 cellular structures were designed and fabricated using the SLS 3D printer with a new unconventional approach in adjusting the settings of the machine, and their mechanical properties were extracted. The structures' internal properties were evaluated using the FESEM. Comparing the mechanical compressive test results showed that adjustments in material and geometry improved mechanical properties (such as the compressive moduli, compressive strength, and yield strength). For instance, in 3 mm samples, the elastic modulus in material gradient and geometrical gradient structures is 20% and 73 % higher than the minimum values of the uniform structure. FESEM imaging revealed that adjusting the absorbed energy by powders (controlled by laser characteristics) leads to the formation of natural voids with diameters in the range of 6 to 144 μm for the gradient structures. Evaluation of the designed structures showed that 6 of them (4 uniform porosity and 2 geometrically gradient) have mechanical behavior of the desired tissue. The research outcomes can assist in optimizing manufactured parts by SLS 3D printers with internal and external controlled properties to obtain more desirable mechanical characteristics, especially for tissue engineering applications. تفاصيل المقالة