Introduction: Cardiac natriuretic peptides (NPs) play an important role in the regulation of energy expenditure in skeletal muscle and adipose tissue. A systematic review on the effects of exercise on NPs in patients with heart failure reported that aerobic and resistance training reduced NPs; however, the effects of exercise on NPs and the underlying mechanism of exercise-induced NP secretion in sedentary subjects remain unknown. The aim of this study was to determine the effect of a single bout of circuit resistance training on aminoterminal propeptide (NT-proBNP) levels in sedentary men. Material & Methods: In this study, Fifteen healthy male (aged: 24.5 ± 1.2 years; ± SD) volunteered to participate in this study. The subjects were performed circuit resistance training consisted of 8 stations in the following order: chest press, barbell shoulder press, seated cable rows, barbell curl, overhead triceps extension, curl up, squat and hamstring with machine. This training was circularly performed in 8 stations and included 4 sets with 6 maximal repetitions at 70% of 1-RM in each station. Each circuit and set was separated by 5 min and 30 s rest respectively. NT-proBNP plasma concentrations were measured before and immediately after the resistance training. Paired-sample t- test was used to analyze the data. Results: The results demonstrated that NT-proBNP levels were increased significantly after the circuit resistance training (27.76% and P=0.01). Conclusions: In conclusion, a single bout of circuit resistance training in sedentary men led to a fast rise of plasma NT-proBNP concentrations. تفاصيل المقالة

Introduction: Elevated levels of galectin-3 have been found to be significantly associated with higher risk of death in both acute decompensate heart failure and chronic heart failure populations. Although endurance exercise is a crucial element in cardiovascular disease prevention, the relationship between exercise and plasma levels of galectin-3 is still unknown. The aim of this study was to determine the effect of an exhaustive aerobic exercise on galectin-3 levels in healthy males. Material & Methods: Fifteen healthy male (aged: 22.2 ± 2.3 years; ± SD) volunteered to participate in this study. The subjects were performed Bruce protocol as the exhaustive aerobic exercise. The blood sample was taken before and immediately after the completion of the exhaustive aerobic exercise. Wilcoxon test and Spearman correlation test were used to analyze the data. Results: The results demonstrated that galectin-3 had no significant changes in response to the exhaustive aerobic exercise (297.6 ± 180.5 vs. 294.9 ± 190.3 pg/ml). No significant correlation was observed between the post-exercise levels of galectin-3 with body mass (r = 0.1, P = 0.7), BMI (r = ‒ 0.1, P = 0.7), body fat percentage (r = 0.06, P = 0.8), WHR (r = 0.02, P = 0.9), or VO2max (r = 0.2, P = 0.4). Conclusions: In conclusion, the exhaustive aerobic exercise had not significant effects on galectin-3 concentrations in healthy individuals. تفاصيل المقالة

Introduction: Many studies documented the relationship between elevated plasma concentrations of brain natriuretic peptide (BNP) and its aminoterminal propeptide (NT-proBNP) and cardiovascular diseases, especially heart failure (HF). However, it is still uncertain whether physical exercise leads to a significant release of NT-proBNP in healthy subjects. The aim of this study was to determine the effect of an exhaustive aerobic exercise on NT-proBNP levels in healthy males. Material & Methods: In this study, Fifteen healthy male (aged: 22.2 ± 2.3 years; ± SD) volunteered to participate in this study. The subjects were performed Bruce protocol as the exhaustive aerobic exercise. NT-proBNP plasma concentrations were measured before and immediately after the exhaustive aerobic exercise. Paired-sample t- test was used to analyze the data. Results: The results demonstrated that NT-proBNP levels were increased significantly after the exhaustive aerobic exercise (P<0.05). We did not find any correlation between the post-exercise increase of NT-proBNP levels and body mass index (BMI), body fat percentage (%BF) or VO2max. Conclusions: In conclusion, the exhaustive aerobic exercise in healthy individuals led to a fast rise of plasma NT-proBNP concentrations. تفاصيل المقالة