The Biginelli Reaction is a one-pot acid catalysed cyclocondensation of -keto ester, urea and aromatic aldehyde which leads to the synthesis of functionalised 3,4-dihydro-2(H)-pyrimidinones (DHPMs). This three-component reaction for the synthesis of dihydropyrimidinone and corresponding dihydropyrimidinethiones has now been known for more than a century since first reported in 1893. The classical reaction has been modified in the recent past by using various catalysts and several structural variants in different solvents to synthesize large number of Biginelli type compounds. Also, these DHPMs (synthetic and natural) possess a wide range of pharmacological activities. تفاصيل المقالة

در این مطالعه، اکسید مس به‌عنوان یک جاذب خوب و ارزان برای حذف رنگ‌های اریتروزین و کارموزین قرمز از چندین محلول آبی با موفقیت معرفی و مورد استفاده قرار گرفته است. تأثیر پارامترهای مختلف مانند pH ، غلظت رنگ، مقدار جاذب، زمان تماس و دما بر فرآیند حذف بررسی شد. داده‌های هم‌دما جذب را می‌توان با مدل‌های ایزوترم لانگمویر و فروندلیچ تفسیر کرد. مقادیر K بالاتر از 103/43 و 162/10 میلی‌گرم در لیتر برای اریتروزین و کارموزین قرمز نشان می‌دهد که اکسید مس در مقایسه با سایر جاذب‌ها میل ترکیبی بیشتری برای رنگ‌ها دارد تفاصيل المقالة

Oxidative coupling of thiols to the corresponding symmetrical disulfides were performed in the presence of silica gel supported tributylammonium fluorochromate(VI), (TriBAFC), and tributylammonium chlorochromate(VI), (TriBACC). Silica gel supported TriBAFC and TriBACC are versatile reagents for the effective and selective oxidation of organic substrates, in particular of thiol, under mild conditions. Disulfides are also key intermediates in a wide variety of organic synthetic routes .Considerable improvements are observed in the presence of the absorbent and making the work-up much more convenient. The nature of the solvent does not appear to be particularly critical. Hydrocarbons, benzene, ethers and chlorinated hydrocarbons are equally effective, the practical choice being oriented by the solubility of the products and the desired reaction temperature. The IR spectra of TriBAFC and TriBACC are similar to that of other fluoro and chlorochromates, TriBAFC and TriBACC are soluble in water, dimethylformamide, acetonitrile, acetone and dichloromethane; they are only sparingly soluble in benzene, carbon tetrachloride, chloroform and hexane. تفاصيل المقالة