Acid functionalized multi-walled carbon nanotubes/CeO2 (MWCNTs)-COOH/CeO2 hybrid was fabricated by the reaction of functionalized (MWCNTs)-COOH and Ce(NO3)2.6H2O in acetic acid. Synthesis of CeO2 nanoparticles and their conjugation on the surface of (MWCNTs)-COOH have been confirmed by FT-IR, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), and Energy-dispersive X-ray spectroscopy (EDX). The modification of MWCNTs-COOH with CeO2 produced an efficient catalyst for the Claisen–Schmidt condensation, soa large variety of chalconeswere obtained in high yield using a catalytic amount of (MWCNTs)-COOH/CeO2 hybrid (5 mol%). تفاصيل المقالة