In countries having traditional medicine (TM), one of the main challenges for any researcher is research methodology. Current methodologies are different with what was in past. The main purpose of this article is to present the steps (herbs, claims and methodology) of research in TM fields.1. Assessment of herbsHistory, method of study, quality assessment, efficacy, safety, toxicity and therapeutic effect are included in this part.2. Efficacy and safety of herbsBotany, therapeutic effect, toxicology methods, how to study toxicity will be explained in this part.3. Assessment of TM productsThis part contains herb identification, certification, standardization, claims for therapeutic effect, confirmation of safety of herb.4. Claims for efficacy of herbsIt includes various claims, concept, features, base, importance, and evidence to confirm these claims.5. Method of studyThis includes for in vitro/in vivo studies (observational and interventional). In addition, the role of Meta analysis will be discussed.6. Ethical committeeEthics in research, ethical committee, their activity, check list of committee for any study will be explained. تفاصيل المقالة