کاربردهای بالقوه گیاه صبر زرد Alo vere L. در صنایع دارویی، آرایشی، بهداشتی و غذایی- بیوسنتز نانو ذرات: بررسی جامع
الموضوعات :
محمد حیدری
1
(گروه محیط زیست، واحد بوشهر، دانشگاه آزاد اسلامی بوشهر، ایران)
طیبه طباطبایی
2
(گروه محیط زیست، واحد بوشهر، دانشگاه آزاد اسلامی بوشهر، ایران)
فاضل امیری
3
(گروه محیط زیست، واحد بوشهر، دانشگاه آزاد اسلامی بوشهر، ایران)
سید عنایت هاشمی
4
(استاد مدعو، گروه محیط زیست، واحد بوشهر، دانشگاه آزاد اسلامی بوشهر، ایران- گروه مهندسی بهداشت محیط، دانشکده بهداشت و تغذیه، دانشگاه)
الکلمات المفتاحية: ژل, نانوذرات, بیوسنتز, آسیبار, صبر زرد آلوئه ورا (Alo vere L.),
ملخص المقالة :
گیاه صبر زرد، آلوئه ورا (Alo vere L.) یکی از قدیمی ترین و سنتی ترین گیاهان دارویی تاریخ است که قدمت آن به بیش از هزار سال می رسد. امروزه فعالیت بیولوژیکی آن به اهداف درمانی محدود نمی شود. گسترش صنعت صبر زرد آلوئه ورا در طول دهه 90 آشکار شد، زمانی که توسعه این محصول به دلیل تقاضای جهانی از سوی مصرف کنندگان بیشتر به یک سبک زندگی سالم شروع شد. با توجه به ارتباط کشت و صنعت و اقتصادی که این گیاه کسب کرده است، این کار به بررسی ویژگی های شیمیایی، بیولوژیکی و تغذیه ای، روش های فرآوری گیاه، نوآوری ها، بیوسنتز نانو ذرات و کاربردهای صنعتی آن می پردازد. در این مقاله کاربردهای آن در صنایع دارویی، آرایشی و بهداشتی، غذایی ارائه شده است و چشم انداز جهانی بازار میلیون دلاری پیرامون این محصول پرداخته شده است. همچنین، در این بررسی، روش بیوسنتز نانو ذرات را با استفاده از صبر زرد آلوئه ورا به عنوان یک عامل کاهنده آورده شده است. مقالات اخیر نشان داد که از گیاه صبر زرد آلوئه ورا برای تولید نانو مواد از طریق بیوسنتز استفاده شده است. این گیاه دارای ویژگی های منحصر به فرد بسیاری است و به دلیل خواص آنتی اکسیدانی، ضد التهابی، ضد دیابتی، تسکین آفتاب سوختگی، تقویت سیستم ایمنی، ضد پیری و ضد سرطان شناخته شده است. بعلاوه، می توان نتیجه گرفت که نانوذرات بیوسنتز شده با گیاه صبر زرد آلوئه ورا، سازگاری با محیط زیست، ساده، مقرون به صرفه و بی ضرر است.
Ahlawat, K. S., & Khatkar, B. S. 2011. Processing, food applications and safety of aloe vera products: a review. Journal of Food Science and Technology, 48(5), 525-533.
Ahmed, M., & Hussain, F. 2013. Chemical composition and biochemical activity of Aloe vera (Aloe barbadensis Miller) leaves. International Journal of chemical and biochemical sciences, 3(5), 29-33.
Ahmed, N. K., Abbady, A., Elhassan, Y. A., & Said, A. H. 2023. Green Synthesized Titanium Dioxide Nanoparticle from Aloe Vera Extract as a Promising Candidate for Radiosensitization Applications. BioNanoScience.
Alvarado-Morales, G., Minjares-Fuentes, R., Contreras-Esquivel, J. C., Montañez, J., Meza-Velázquez, J. A., & Femenia, A. 2019. Application of thermosonication for Aloe vera (Aloe barbadensis Miller) juice processing: Impact on the functional properties and the main bioactive polysaccharides. Ultrasonics Sonochemistry, 56, 125-133.
Añibarro-Ortega, M., Pinela, J., Barros, L., Ćirić, A., Silva, S. P., Coelho, E., Mocan, A., Calhelha, R. C., Soković, M., & Coimbra, M. A. 2019. Compositional features and bioactive properties of Aloe vera leaf (fillet, mucilage, and rind) and flower. Antioxidants, 8(10), 444.
Antignac, E., Nohynek, G. J., Re, T., Clouzeau, J., & Toutain, H. 2011. Safety of botanical ingredients in personal care products/cosmetics. Food and Chemical Toxicology, 49(2), 324-341.
Baldi, A., Sommella, E., Campiglia, P., & Daglia, M. 2021. Aloe gel-base food products: Chemical, toxicological, and regulatory aspects. Regulatory Toxicology and Pharmacology, 119, 104818.
Baruah, A., Bordoloi, M., & Deka Baruah, H. P. 2016. Aloe vera: A multipurpose industrial crop. Industrial Crops and Products, 94, 951-963.
Basannavar, S., Pothuraju, R., & Sharma, R. K. 2014. Effect of Aloe vera (Aloe barbadensis Miller) on survivability, extent of proteolysis and ACE inhibition of potential probiotic cultures in fermented milk. Journal of the Science of Food and Agriculture, 94(13), 2712-2717.
Borges-Argáez, R., Chan-Balan, R., Cetina-Montejo, L., Ayora-Talavera, G., Sansores-Peraza, P., Gómez-Carballo, J., & Cáceres-Farfán, M. 2019. In vitro evaluation of anthraquinones from Aloe vera (Aloe barbadensis Miller) roots and several derivatives against strains of influenza virus. Industrial Crops and Products, 132, 468-475.
Bozzi, A., Perrin, C., Austin, S., & Arce Vera, F. 2007. Quality and authenticity of commercial aloe vera gel powders. Food Chemistry, 103(1), 22-30.
Canche-Escamilla, G., Colli-Acevedo, P., Borges-Argaez, R., Quintana-Owen, P., May-Crespo, J. F., Cáceres-Farfan, M., Yam Puc, J. A., Sansores-Peraza, P., & Vera-Ku, B. M. 2019. Extraction of phenolic components from an Aloe vera (Aloe barbadensis Miller) crop and their potential as antimicrobials and textile dyes. Sustainable Chemistry and Pharmacy, 14, 100168.
Castillo, S., Navarro, D., Zapata, P. J., Guillén, F., Valero, D., Serrano, M., & Martínez-Romero, D. 2010. Antifungal efficacy of Aloe vera in vitro and its use as a preharvest treatment to maintain postharvest table grape quality. Postharvest Biology and Technology, 57(3), 183-188.
Cavasana, A. L., Santos, C. H. M. d., Dourado, D. M., Guimarães, F. d. S., Barros, F. H. R., de Campos, G. C. O., Leme, G. A. L., Silva, L. D. M. d., Wahl, L. M., & Gutterres, N. B. d. A. 2020. Eficácia do extrato de Aloe Vera no tratamento da fístula anal. Journal of Coloproctology (Rio de Janeiro), 40(1), 67-72.
Chandran, S. P., Chaudhary, M., Pasricha, R., Ahmad, A., & Sastry, M. 2006. Synthesis of gold nanotriangles and silver nanoparticles using Aloevera plant extract. Biotechnology progress, 22(2), 577-583.
Dammak, I., Lasram, S., Hamdi, Z., Ben Moussa, O., Mkadmini Hammi, K., Trigui, I., Houissa, H., Mliki, A., & Hassouna, M. 2018. In vitro antifungal and anti-ochratoxigenic activities of Aloe vera gel against Aspergillus carbonarius isolated from grapes. Industrial Crops and Products, 123, 416-423.
Das, K., Krishna, P., Sarkar, A., Ilangovan, S. S., & Sen, S. 2017. A review on pharmacological properties of Solanum tuberosum. Research Journal of Pharmacy and Technology, 10(5), 1517-1522.
de Rodriguez, D. J., Angulo-Sanchez, J. L., da Silva, J. A. T., & Aguilar-Gonzalez, C. N. 2006. Review of Aloe species' medicinal properties and bioactive compounds. Floriculture, ornamental and plant biotechnology, 460-471.
Denius Jr, H. R., & Homann, P. H. 1972. The relation between photosynthesis, respiration, and Crassulacean acid metabolism in leaf slices of Aloe arborescens Mill. Plant Physiology, 49(6), 873-880.
Domínguez-Fernández, R., Arzate-Vazquez, I., Chanona-Perez, J. J., Welti-Chanes, J., Alvarado-González, J., Calderon-Dominguez, G., Garibay-Febles, V., & Gutierrez-Lopez, G. F. 2012. El gel de Aloe vera: estructura, composición química, procesamiento, actividad biológica e importancia en la industria farmacéutica y alimentaria. Revista mexicana de ingeniería química, 11(1), 23-43.
El-Sayed, S. M., & El-Sayed, H. S. 2020. Production of UF-soft cheese using probiotic bacteria and Aloe vera pulp as a good source of nutrients. Annals of Agricultural Sciences, 65(1), 13-20.
Eshun, K., & He, Q. 2004. Aloe vera: a valuable ingredient for the food, pharmaceutical and cosmetic industries—a review. Critical reviews in food science and nutrition, 44(2), 91-96.
Farhadi, N., Tabatabaie, T., Ramavandi, B., & Amiri, F. 2020. Optimization and characterization of zeolite-titanate for ibuprofen elimination by sonication/hydrogen peroxide/ultraviolet activity. Ultrasonics Sonochemistry, 67, 105122.
Farhadi, N., Tabatabaie, T., Ramavandi, B., & Amiri, F. 2021. Ibuprofen elimination from water and wastewater using sonication/ultraviolet/hydrogen peroxide/zeolite-titanate photocatalyst system. Environmental Research, 198, 111260.
Femenia, A., Sánchez, E. S., Simal, S., & Rosselló, C. 1999. Compositional features of polysaccharides from Aloe vera (Aloe barbadensis Miller) plant tissues. Carbohydrate Polymers, 39(2), 109-117.
Flores-López, M. L., Romaní, A., Cerqueira, M. A., Rodríguez-García, R., Jasso de Rodríguez, D., & Vicente, A. A. 2016. Compositional features and bioactive properties of whole fraction from Aloe vera processing. Industrial Crops and Products, 91, 179-185.
Flórez Martínez, D. H. 2018. Estudio de inteligencia competitiva para la cadena productiva de la sábila.
Gao, Y., Kuok, K. I., Jin, Y., & Wang, R. 2019. Biomedical applications of Aloe vera. Critical reviews in food science and nutrition, 59(sup1), S244-S256.
Ghani, U., Naeem, M., Rafeeq, H., Imtiaz, U., Amjad, A., Ullah, S., Rehman, A., & Qasim, F. 2019. A novel approach towards nutraceuticals and biomedical applications. Sch Int. J. Biochem, 2, 245-252.
Guerrero-Beltr· n, J., & Barbosa-C· novas, G. 2004. Advantages and limitations on processing foods by UV light. Food science and technology international, 10(3), 1.37-147.
Gunalan, S., Sivaraj, R., & Rajendran, V. 2012. Green synthesized ZnO nanoparticles against bacterial and fungal pathogens. Progress in Natural Science: Materials International, 22(6), 693-700.
Hamman, J. 2008. Composition and applications of Ocimum gratissimum leaf. Molecules, 13(8), 1599-1616.
Heydari, M., Tabatabaie, T., Amiri, F., & Hashemi, S. E. 2023a. BTEXS Removal From Aqueous Phase by MCM-41 Green Synthesis Using Rice Husk Silica. Iranica Journal of Energy & Environment, 14(4), 321-335.
Heydari, M., Tabatabaie, T., Amiri, F., & Hashemi, S. E. 2023b. Comparative study of green synthesis of nanoparticles for removal of oily industrial wastewater by Taguchi method. International Journal of Environmental Science and Technology.
Heydari, M., Tabatabaie, T., Amiri, F., & Hashemi, S. E. 2023. Investigating photocatalytic removal of BTEXS in aqueous solution using a green synthesis of ALV-TiO2/Co-MCM-41 nanocomposite under visible light. Biomass Conversion and Biorefinery.
Huang, C.-T., Hung, C.-Y., Hseih, Y.-C., Chang, C.-S., Velu, A. B., He, Y.-C., Huang, Y.-L., Chen, T.-A., Chen, T.-C., Lin, C.-Y., Lin, Y.-C., Shih, S.-R., & Dutta, A. 2019. Effect of aloin on viral neuraminidase and hemagglutinin-specific T cell immunity in acute influenza. Phytomedicine, 64, 152904.
Hussain, S. A., Patil, G. R., Reddi, S., Yadav, V., Pothuraju, R., Singh, R. R. B., & Kapila, S. 2017. Aloe vera (Aloe barbadensis Miller) supplemented probiotic lassi prevents Shigella infiltration from epithelial barrier into systemic blood flow in mice model. Microbial Pathogenesis, 102, 143-147.
Javed, S., & Atta ur, R. (2014). Chapter 9 - Aloe Vera Gel in Food, Health Products, and Cosmetics Industry. In R. Atta ur (Ed.), Studies in Natural Products Chemistry. 41, 261-285).
Khatri, D., Panigrahi, J., Prajapati, A., & Bariya, H. 2020. Attributes of Aloe vera gel and chitosan treatments on the quality and biochemical traits of post-harvest tomatoes. Scientia Horticulturae, 259, 108837.
Kluge, M., Knapp, I., Kramer, D., Schwerdtner, I., & Ritter, H. 1979. Crassulacean acid metabolism (CAM) in leaves of Aloe arborescens Mill. Planta, 145(4), 357-363.
Liontakis, A., Sintori, A., & Tzouramani, I. 2021. The Role of the Start-Up Aid for Young Farmers in the Adoption of Innovative Agricultural Activities: The Case of Aloe Vera. Agriculture, 11(4), 349.
López-Cervantes, J., Sánchez-Machado, D. I., Cruz-Flores, P., Mariscal-Domínguez, M. F., Servín de la Mora-López, G., & Campas-Baypoli, O. N. 2018. Antioxidant capacity, proximate composition, and lipid constituents of Aloe vera flowers. Journal of Applied Research on Medicinal and Aromatic Plants, 10, 93-98.
López-Cervantes, J., Sendón, R., Sanches-Silva, A., & Sánchez-Machado, D. 2017. Aloe vera: Ancient knowledge with new frontiers. Trends Food Sci. Technol, 61, 94-102.
Maan, A. A., Nazir, A., Khan, M. K. I., Ahmad, T., Zia, R., Murid, M., & Abrar, M. 2018. The therapeutic properties and applications of Aloe vera: A review. Journal of Herbal Medicine, 12, 1-10.
Majumder, R., Das, C. K., & Mandal, M. 2019. Lead bioactive compounds of Aloe vera as potential anticancer agent. Pharmacological Research, 148, 104416.
Manvitha, K., & Bidya, B. 2014. Aloe vera: a wonder plant its history, cultivation and medicinal uses. Journal of Pharmacognosy and Phytochemistry, 2(5), 85-88.
Maret, R. H. (1975). Process for preparing extracts of Aloe vera. In: Google Patents.
Martínez-Burgos, W. J., Serra, J. L., MarsigliaF, R. M., Montoya, P., Sarmiento-Vásquez, Z., Marin, O., Gallego-Cartagena, E., & Paternina-Arboleda, C. D. 2022. Aloe vera: From ancient knowledge to the patent and innovation landscape – A review. South African Journal of Botany, 147.993-1006.
Martínez, E., Criollo, J., Calderón, C., & Torres, R. 2017. Pruebas de cocción de pastas alimenticias elaboradas con harina de trigo-almidón de banano. Cumbres, 4(1), 9-16.
Maughan, R. G. (1984). Controlled temperature process for manufacturing of improved stabilized aloe vera. In: Google Patents.
Mukherjee, P. K., Nema, N. K., Maity, N., Mukherjee, K., & Harwansh, R. K. 2014. Phytochemical and therapeutic profile of Aloe vera. Journal of Natural Remedies, 1-26.
Nagaraj, G., Brundha, D., Kowsalya, V., Chandraleka, C., Sangavi, S., Jayalakshmi, R., Arulpriya, M., Sathya, N., Prasath, M., & Tamilarasu, S. 2021. Biosynthesis of zinc doped Aloe Vera for green nanoparticles. Materials Today: Proceedings, 43, 3354-3358.
Nicolau-Lapeña, I., Aguiló-Aguayo, I., Kramer, B., Abadias, M., Viñas, I., & Muranyi, P. 2021. Combination of ferulic acid with Aloe vera gel or alginate coatings for shelf-life prolongation of fresh-cut apples. Food Packaging and Shelf Life, 27, 100620.
Nithya, A., Rokesh, K., & Jothivenkatachalam, K. 2013. Biosynthesis, characterization and application of titanium dioxide nanoparticles. Nano vision, 3(3), 169-174.
Ortega-Toro, R., Collazo-Bigliardi, S., Roselló, J., Santamarina, P., & Chiralt, A. 2017. Antifungal starch-based edible films containing Aloe vera. Food Hydrocolloids, 72, 1-10.
Pandey, A., & Singh, S. 2016. Aloe Vera: A Systematic Review of its Industrial and Ethno-Medicinal Efficacy. International Journal of Pharmaceutical Research & Allied Sciences, 5.(1).
Patra, J. K., Kwon, Y., & Baek, K.-H. 2016. Green biosynthesis of gold nanoparticles by onion peel extract: Synthesis, characterization and biological activities. Advanced Powder Technology, 27(5), 2204-2213.
Priya, G. S., Kanneganti, A., Kumar, K. A., Rao, K. V., & Bykkam, S. 2014. Biosynthesis of Cerium oxide nanoparticles using Aloe barbadensis miller gel. Int J Sci Res Publ, 4(6), 199-224.
Raygan Shirazi Nejad, A. R., Jorfi, S., Tabatabaei, T., & Amiri, F. 2022. Photocatalytic Degradation of Gentamicin Antibiotics Using Fe3O4 / SiO2 / TiO2 Nanocomposites Synthesized in Aqueous Solutions in the Presence of Sunlight. yums-armaghan, 27(3), 349-364.
Reynolds, T., & Dweck, A. C. 1999. Aloe vera leaf gel: a review update. Journal of Ethnopharmacology, 68(1), 3-37.
Rodríguez-Rodríguez, M. Z., Meléndez-Pizarro, C. O., Espinoza-Hicks, J. C., Quintero-Ramos, A., Sánchez-Madrigal, M. Á., Meza-Velázquez, J. A., & Jiménez-Castro, J. A. 2019. Effects of UV-C irradiation and traditional thermal processing on acemannan contained in Aloe vera gel blends. Carbohydrate Polymers, 222, 114998.
Ronald, M., Shelton, M., & Usaf, M. 1991. Aloe vera: its chemical and therapeutic properties. Int J dermatol, 30(10), 679-673.
Rumpf, H. 1990. The characteristics of systems and their changes of state disperse. Particle Technology, Chapman and Hall; Springer: Berlin/Heidelberg, Germany, 8-54.
Sahu, P. K., Giri, D. D., Singh, R., Pandey, P., Gupta, S., Shrivastava, A. K., Kumar, A., & Pandey, K. D. 2013. Therapeutic and medicinal uses of Aloe vera: a review. Pharmacology & Pharmacy, 4(08), 599.
Sangeetha, G., Rajeshwari, S., & Venckatesh, R. 2011. Green synthesis of zinc oxide nanoparticles by aloe barbadensis miller leaf extract: Structure and optical properties. Materials Research Bulletin, 46(12), 2560-2566.
Scala, K. D., Vega-Gálvez, A., Ah-Hen, K., Nuñez-Mancilla, Y., Tabilo-Munizaga, G., Pérez-Won, M., & Giovagnoli, C. 2013. Chemical and physical properties of aloe vera (Aloe barbadensis Miller) gel stored after high hydrostatic pressure processing. Food Science and Technology, 33, 52-59.
Steenkamp, E. 2015. A profile on the aloe industry for export-A focus on South Africa. Directorate International Trade, Department of Agriculture. Forestry and Fisheries, Pretoria.
Steenkamp, V., & Stewart, M. 2007. Medicinal applications and toxicological activities of Aloe. Products. Pharmaceutical biology, 45(5), 411-420.
Tavasol, F., Tabatabaie, T., Ramavandi, B., & Amiri, F. 2021. Photocatalyst production from wasted sediment and quality improvement with titanium dioxide to remove cephalexin in the presence of hydrogen peroxide and ultrasonic waves: A cost-effective technique. Chemosphere, 284, 131337.
Teplicki, E., Ma, Q., Castillo, D. E., Zarei, M., Hustad, A. P., Chen, J., & Li, J. 2018. The effects of aloe vera on wound healing in cell proliferation, migration, and viability. Wounds: a compendium of clinical research and practice, 30(9), 263-268.
Vandenberghe, L. d. S., Pandey, A., Carvalho, J. d., Letti, L., Woiciechowski, A., Karp, S., Thomaz-Soccol, V., Martínez-Burgos, W., Penha, R. d. O., & Herrmann, L. 2020. Solid-state fermentation tech-nology and innovation for the production of agricultural and animal feed bioprod-ucts. Syst. Microbiol. Biomanufact. 1, 142–165. In.
Vargas Hernández, J., Coste, S., García Murillo, A., Carrillo Romo, F., & Kassiba, A. 2017. Effects of metal doping (Cu, Ag, Eu) on the electronic and optical behavior of nanostructured TiO2. Journal of Alloys and Compounds, 710, 355-363.
Vega-Gálvez, A., Uribe, E., Perez, M., Tabilo-Munizaga, G., Vergara, J., Garcia-Segovia, P., Lara, E., & Di Scala, K. 2011. Effect of high hydrostatic pressure pretreatment on drying kinetics, antioxidant activity, firmness and microstructure of Aloe vera (Aloe barbadensis Miller) gel. LWT - Food Science and Technology, 44(2), 384-391.
Vega, A., Ampuero, N., Díaz, L., & Lemus, R. 2005. El Aloe vera (Aloe barbadensis Miller) como componente de alimentos funcionales. Revista chilena de nutrición, 32(3), 208-214.
Vickers, N. J. 2017. Animal Communication: When I’m Calling You, Will You Answer Too? Current Biology, 27(14), R713-R715.
Vijayaraghavan, K., & Ashokkumar, T. 2017. Plant-mediated biosynthesis of metallic nanoparticles: A review of literature, factors affecting synthesis, characterization techniques and applications. Journal of Environmental Chemical Engineering, 5(5), 4866-488.
Vinson, J. A., Al Kharrat, H., & Andreoli, L. 2005. Effect of Aloe vera preparations on the human bioavailability of vitamins C and E. Phytomedicine, 12(10), 760-765.
Yuvasree, P., Nithya, K., & Neelakandeswari, N. (2013, 24-26 July 2013). Biosynthesis of silver nanoparticles from Aloe vera plant extract and its antimicrobial activity against multidrug resistant pathogens. International Conference on Advanced Nanomaterials & Emerging Engineering Technologies,
Zapata, P. J., Navarro, D., Guillén, F., Castillo, S., Martínez-Romero, D., Valero, D., & Serrano, M. 2013. Characterisation of gels from different Aloe spp. as antifungal treatment: Potential crops for industrial applications. Industrial Crops and Products, 42, 223-230.
_||_Ahlawat, K. S., & Khatkar, B. S. 2011. Processing, food applications and safety of aloe vera products: a review. Journal of Food Science and Technology, 48(5), 525-533.
Ahmed, M., & Hussain, F. 2013. Chemical composition and biochemical activity of Aloe vera (Aloe barbadensis Miller) leaves. International Journal of chemical and biochemical sciences, 3(5), 29-33.
Ahmed, N. K., Abbady, A., Elhassan, Y. A., & Said, A. H. 2023. Green Synthesized Titanium Dioxide Nanoparticle from Aloe Vera Extract as a Promising Candidate for Radiosensitization Applications. BioNanoScience.
Alvarado-Morales, G., Minjares-Fuentes, R., Contreras-Esquivel, J. C., Montañez, J., Meza-Velázquez, J. A., & Femenia, A. 2019. Application of thermosonication for Aloe vera (Aloe barbadensis Miller) juice processing: Impact on the functional properties and the main bioactive polysaccharides. Ultrasonics Sonochemistry, 56, 125-133.
Añibarro-Ortega, M., Pinela, J., Barros, L., Ćirić, A., Silva, S. P., Coelho, E., Mocan, A., Calhelha, R. C., Soković, M., & Coimbra, M. A. 2019. Compositional features and bioactive properties of Aloe vera leaf (fillet, mucilage, and rind) and flower. Antioxidants, 8(10), 444.
Antignac, E., Nohynek, G. J., Re, T., Clouzeau, J., & Toutain, H. 2011. Safety of botanical ingredients in personal care products/cosmetics. Food and Chemical Toxicology, 49(2), 324-341.
Baldi, A., Sommella, E., Campiglia, P., & Daglia, M. 2021. Aloe gel-base food products: Chemical, toxicological, and regulatory aspects. Regulatory Toxicology and Pharmacology, 119, 104818.
Baruah, A., Bordoloi, M., & Deka Baruah, H. P. 2016. Aloe vera: A multipurpose industrial crop. Industrial Crops and Products, 94, 951-963.
Basannavar, S., Pothuraju, R., & Sharma, R. K. 2014. Effect of Aloe vera (Aloe barbadensis Miller) on survivability, extent of proteolysis and ACE inhibition of potential probiotic cultures in fermented milk. Journal of the Science of Food and Agriculture, 94(13), 2712-2717.
Borges-Argáez, R., Chan-Balan, R., Cetina-Montejo, L., Ayora-Talavera, G., Sansores-Peraza, P., Gómez-Carballo, J., & Cáceres-Farfán, M. 2019. In vitro evaluation of anthraquinones from Aloe vera (Aloe barbadensis Miller) roots and several derivatives against strains of influenza virus. Industrial Crops and Products, 132, 468-475.
Bozzi, A., Perrin, C., Austin, S., & Arce Vera, F. 2007. Quality and authenticity of commercial aloe vera gel powders. Food Chemistry, 103(1), 22-30.
Canche-Escamilla, G., Colli-Acevedo, P., Borges-Argaez, R., Quintana-Owen, P., May-Crespo, J. F., Cáceres-Farfan, M., Yam Puc, J. A., Sansores-Peraza, P., & Vera-Ku, B. M. 2019. Extraction of phenolic components from an Aloe vera (Aloe barbadensis Miller) crop and their potential as antimicrobials and textile dyes. Sustainable Chemistry and Pharmacy, 14, 100168.
Castillo, S., Navarro, D., Zapata, P. J., Guillén, F., Valero, D., Serrano, M., & Martínez-Romero, D. 2010. Antifungal efficacy of Aloe vera in vitro and its use as a preharvest treatment to maintain postharvest table grape quality. Postharvest Biology and Technology, 57(3), 183-188.
Cavasana, A. L., Santos, C. H. M. d., Dourado, D. M., Guimarães, F. d. S., Barros, F. H. R., de Campos, G. C. O., Leme, G. A. L., Silva, L. D. M. d., Wahl, L. M., & Gutterres, N. B. d. A. 2020. Eficácia do extrato de Aloe Vera no tratamento da fístula anal. Journal of Coloproctology (Rio de Janeiro), 40(1), 67-72.
Chandran, S. P., Chaudhary, M., Pasricha, R., Ahmad, A., & Sastry, M. 2006. Synthesis of gold nanotriangles and silver nanoparticles using Aloevera plant extract. Biotechnology progress, 22(2), 577-583.
Dammak, I., Lasram, S., Hamdi, Z., Ben Moussa, O., Mkadmini Hammi, K., Trigui, I., Houissa, H., Mliki, A., & Hassouna, M. 2018. In vitro antifungal and anti-ochratoxigenic activities of Aloe vera gel against Aspergillus carbonarius isolated from grapes. Industrial Crops and Products, 123, 416-423.
Das, K., Krishna, P., Sarkar, A., Ilangovan, S. S., & Sen, S. 2017. A review on pharmacological properties of Solanum tuberosum. Research Journal of Pharmacy and Technology, 10(5), 1517-1522.
de Rodriguez, D. J., Angulo-Sanchez, J. L., da Silva, J. A. T., & Aguilar-Gonzalez, C. N. 2006. Review of Aloe species' medicinal properties and bioactive compounds. Floriculture, ornamental and plant biotechnology, 460-471.
Denius Jr, H. R., & Homann, P. H. 1972. The relation between photosynthesis, respiration, and Crassulacean acid metabolism in leaf slices of Aloe arborescens Mill. Plant Physiology, 49(6), 873-880.
Domínguez-Fernández, R., Arzate-Vazquez, I., Chanona-Perez, J. J., Welti-Chanes, J., Alvarado-González, J., Calderon-Dominguez, G., Garibay-Febles, V., & Gutierrez-Lopez, G. F. 2012. El gel de Aloe vera: estructura, composición química, procesamiento, actividad biológica e importancia en la industria farmacéutica y alimentaria. Revista mexicana de ingeniería química, 11(1), 23-43.
El-Sayed, S. M., & El-Sayed, H. S. 2020. Production of UF-soft cheese using probiotic bacteria and Aloe vera pulp as a good source of nutrients. Annals of Agricultural Sciences, 65(1), 13-20.
Eshun, K., & He, Q. 2004. Aloe vera: a valuable ingredient for the food, pharmaceutical and cosmetic industries—a review. Critical reviews in food science and nutrition, 44(2), 91-96.
Farhadi, N., Tabatabaie, T., Ramavandi, B., & Amiri, F. 2020. Optimization and characterization of zeolite-titanate for ibuprofen elimination by sonication/hydrogen peroxide/ultraviolet activity. Ultrasonics Sonochemistry, 67, 105122.
Farhadi, N., Tabatabaie, T., Ramavandi, B., & Amiri, F. 2021. Ibuprofen elimination from water and wastewater using sonication/ultraviolet/hydrogen peroxide/zeolite-titanate photocatalyst system. Environmental Research, 198, 111260.
Femenia, A., Sánchez, E. S., Simal, S., & Rosselló, C. 1999. Compositional features of polysaccharides from Aloe vera (Aloe barbadensis Miller) plant tissues. Carbohydrate Polymers, 39(2), 109-117.
Flores-López, M. L., Romaní, A., Cerqueira, M. A., Rodríguez-García, R., Jasso de Rodríguez, D., & Vicente, A. A. 2016. Compositional features and bioactive properties of whole fraction from Aloe vera processing. Industrial Crops and Products, 91, 179-185.
Flórez Martínez, D. H. 2018. Estudio de inteligencia competitiva para la cadena productiva de la sábila.
Gao, Y., Kuok, K. I., Jin, Y., & Wang, R. 2019. Biomedical applications of Aloe vera. Critical reviews in food science and nutrition, 59(sup1), S244-S256.
Ghani, U., Naeem, M., Rafeeq, H., Imtiaz, U., Amjad, A., Ullah, S., Rehman, A., & Qasim, F. 2019. A novel approach towards nutraceuticals and biomedical applications. Sch Int. J. Biochem, 2, 245-252.
Guerrero-Beltr· n, J., & Barbosa-C· novas, G. 2004. Advantages and limitations on processing foods by UV light. Food science and technology international, 10(3), 1.37-147.
Gunalan, S., Sivaraj, R., & Rajendran, V. 2012. Green synthesized ZnO nanoparticles against bacterial and fungal pathogens. Progress in Natural Science: Materials International, 22(6), 693-700.
Hamman, J. 2008. Composition and applications of Ocimum gratissimum leaf. Molecules, 13(8), 1599-1616.
Heydari, M., Tabatabaie, T., Amiri, F., & Hashemi, S. E. 2023a. BTEXS Removal From Aqueous Phase by MCM-41 Green Synthesis Using Rice Husk Silica. Iranica Journal of Energy & Environment, 14(4), 321-335.
Heydari, M., Tabatabaie, T., Amiri, F., & Hashemi, S. E. 2023b. Comparative study of green synthesis of nanoparticles for removal of oily industrial wastewater by Taguchi method. International Journal of Environmental Science and Technology.
Heydari, M., Tabatabaie, T., Amiri, F., & Hashemi, S. E. 2023. Investigating photocatalytic removal of BTEXS in aqueous solution using a green synthesis of ALV-TiO2/Co-MCM-41 nanocomposite under visible light. Biomass Conversion and Biorefinery.
Huang, C.-T., Hung, C.-Y., Hseih, Y.-C., Chang, C.-S., Velu, A. B., He, Y.-C., Huang, Y.-L., Chen, T.-A., Chen, T.-C., Lin, C.-Y., Lin, Y.-C., Shih, S.-R., & Dutta, A. 2019. Effect of aloin on viral neuraminidase and hemagglutinin-specific T cell immunity in acute influenza. Phytomedicine, 64, 152904.
Hussain, S. A., Patil, G. R., Reddi, S., Yadav, V., Pothuraju, R., Singh, R. R. B., & Kapila, S. 2017. Aloe vera (Aloe barbadensis Miller) supplemented probiotic lassi prevents Shigella infiltration from epithelial barrier into systemic blood flow in mice model. Microbial Pathogenesis, 102, 143-147.
Javed, S., & Atta ur, R. (2014). Chapter 9 - Aloe Vera Gel in Food, Health Products, and Cosmetics Industry. In R. Atta ur (Ed.), Studies in Natural Products Chemistry. 41, 261-285).
Khatri, D., Panigrahi, J., Prajapati, A., & Bariya, H. 2020. Attributes of Aloe vera gel and chitosan treatments on the quality and biochemical traits of post-harvest tomatoes. Scientia Horticulturae, 259, 108837.
Kluge, M., Knapp, I., Kramer, D., Schwerdtner, I., & Ritter, H. 1979. Crassulacean acid metabolism (CAM) in leaves of Aloe arborescens Mill. Planta, 145(4), 357-363.
Liontakis, A., Sintori, A., & Tzouramani, I. 2021. The Role of the Start-Up Aid for Young Farmers in the Adoption of Innovative Agricultural Activities: The Case of Aloe Vera. Agriculture, 11(4), 349.
López-Cervantes, J., Sánchez-Machado, D. I., Cruz-Flores, P., Mariscal-Domínguez, M. F., Servín de la Mora-López, G., & Campas-Baypoli, O. N. 2018. Antioxidant capacity, proximate composition, and lipid constituents of Aloe vera flowers. Journal of Applied Research on Medicinal and Aromatic Plants, 10, 93-98.
López-Cervantes, J., Sendón, R., Sanches-Silva, A., & Sánchez-Machado, D. 2017. Aloe vera: Ancient knowledge with new frontiers. Trends Food Sci. Technol, 61, 94-102.
Maan, A. A., Nazir, A., Khan, M. K. I., Ahmad, T., Zia, R., Murid, M., & Abrar, M. 2018. The therapeutic properties and applications of Aloe vera: A review. Journal of Herbal Medicine, 12, 1-10.
Majumder, R., Das, C. K., & Mandal, M. 2019. Lead bioactive compounds of Aloe vera as potential anticancer agent. Pharmacological Research, 148, 104416.
Manvitha, K., & Bidya, B. 2014. Aloe vera: a wonder plant its history, cultivation and medicinal uses. Journal of Pharmacognosy and Phytochemistry, 2(5), 85-88.
Maret, R. H. (1975). Process for preparing extracts of Aloe vera. In: Google Patents.
Martínez-Burgos, W. J., Serra, J. L., MarsigliaF, R. M., Montoya, P., Sarmiento-Vásquez, Z., Marin, O., Gallego-Cartagena, E., & Paternina-Arboleda, C. D. 2022. Aloe vera: From ancient knowledge to the patent and innovation landscape – A review. South African Journal of Botany, 147.993-1006.
Martínez, E., Criollo, J., Calderón, C., & Torres, R. 2017. Pruebas de cocción de pastas alimenticias elaboradas con harina de trigo-almidón de banano. Cumbres, 4(1), 9-16.
Maughan, R. G. (1984). Controlled temperature process for manufacturing of improved stabilized aloe vera. In: Google Patents.
Mukherjee, P. K., Nema, N. K., Maity, N., Mukherjee, K., & Harwansh, R. K. 2014. Phytochemical and therapeutic profile of Aloe vera. Journal of Natural Remedies, 1-26.
Nagaraj, G., Brundha, D., Kowsalya, V., Chandraleka, C., Sangavi, S., Jayalakshmi, R., Arulpriya, M., Sathya, N., Prasath, M., & Tamilarasu, S. 2021. Biosynthesis of zinc doped Aloe Vera for green nanoparticles. Materials Today: Proceedings, 43, 3354-3358.
Nicolau-Lapeña, I., Aguiló-Aguayo, I., Kramer, B., Abadias, M., Viñas, I., & Muranyi, P. 2021. Combination of ferulic acid with Aloe vera gel or alginate coatings for shelf-life prolongation of fresh-cut apples. Food Packaging and Shelf Life, 27, 100620.
Nithya, A., Rokesh, K., & Jothivenkatachalam, K. 2013. Biosynthesis, characterization and application of titanium dioxide nanoparticles. Nano vision, 3(3), 169-174.
Ortega-Toro, R., Collazo-Bigliardi, S., Roselló, J., Santamarina, P., & Chiralt, A. 2017. Antifungal starch-based edible films containing Aloe vera. Food Hydrocolloids, 72, 1-10.
Pandey, A., & Singh, S. 2016. Aloe Vera: A Systematic Review of its Industrial and Ethno-Medicinal Efficacy. International Journal of Pharmaceutical Research & Allied Sciences, 5.(1).
Patra, J. K., Kwon, Y., & Baek, K.-H. 2016. Green biosynthesis of gold nanoparticles by onion peel extract: Synthesis, characterization and biological activities. Advanced Powder Technology, 27(5), 2204-2213.
Priya, G. S., Kanneganti, A., Kumar, K. A., Rao, K. V., & Bykkam, S. 2014. Biosynthesis of Cerium oxide nanoparticles using Aloe barbadensis miller gel. Int J Sci Res Publ, 4(6), 199-224.
Raygan Shirazi Nejad, A. R., Jorfi, S., Tabatabaei, T., & Amiri, F. 2022. Photocatalytic Degradation of Gentamicin Antibiotics Using Fe3O4 / SiO2 / TiO2 Nanocomposites Synthesized in Aqueous Solutions in the Presence of Sunlight. yums-armaghan, 27(3), 349-364.
Reynolds, T., & Dweck, A. C. 1999. Aloe vera leaf gel: a review update. Journal of Ethnopharmacology, 68(1), 3-37.
Rodríguez-Rodríguez, M. Z., Meléndez-Pizarro, C. O., Espinoza-Hicks, J. C., Quintero-Ramos, A., Sánchez-Madrigal, M. Á., Meza-Velázquez, J. A., & Jiménez-Castro, J. A. 2019. Effects of UV-C irradiation and traditional thermal processing on acemannan contained in Aloe vera gel blends. Carbohydrate Polymers, 222, 114998.
Ronald, M., Shelton, M., & Usaf, M. 1991. Aloe vera: its chemical and therapeutic properties. Int J dermatol, 30(10), 679-673.
Rumpf, H. 1990. The characteristics of systems and their changes of state disperse. Particle Technology, Chapman and Hall; Springer: Berlin/Heidelberg, Germany, 8-54.
Sahu, P. K., Giri, D. D., Singh, R., Pandey, P., Gupta, S., Shrivastava, A. K., Kumar, A., & Pandey, K. D. 2013. Therapeutic and medicinal uses of Aloe vera: a review. Pharmacology & Pharmacy, 4(08), 599.
Sangeetha, G., Rajeshwari, S., & Venckatesh, R. 2011. Green synthesis of zinc oxide nanoparticles by aloe barbadensis miller leaf extract: Structure and optical properties. Materials Research Bulletin, 46(12), 2560-2566.
Scala, K. D., Vega-Gálvez, A., Ah-Hen, K., Nuñez-Mancilla, Y., Tabilo-Munizaga, G., Pérez-Won, M., & Giovagnoli, C. 2013. Chemical and physical properties of aloe vera (Aloe barbadensis Miller) gel stored after high hydrostatic pressure processing. Food Science and Technology, 33, 52-59.
Steenkamp, E. 2015. A profile on the aloe industry for export-A focus on South Africa. Directorate International Trade, Department of Agriculture. Forestry and Fisheries, Pretoria.
Steenkamp, V., & Stewart, M. 2007. Medicinal applications and toxicological activities of Aloe. Products. Pharmaceutical biology, 45(5), 411-420.
Tavasol, F., Tabatabaie, T., Ramavandi, B., & Amiri, F. 2021. Photocatalyst production from wasted sediment and quality improvement with titanium dioxide to remove cephalexin in the presence of hydrogen peroxide and ultrasonic waves: A cost-effective technique. Chemosphere, 284, 131337.
Teplicki, E., Ma, Q., Castillo, D. E., Zarei, M., Hustad, A. P., Chen, J., & Li, J. 2018. The effects of aloe vera on wound healing in cell proliferation, migration, and viability. Wounds: a compendium of clinical research and practice, 30(9), 263-268.
Vandenberghe, L. d. S., Pandey, A., Carvalho, J. d., Letti, L., Woiciechowski, A., Karp, S., Thomaz-Soccol, V., Martínez-Burgos, W., Penha, R. d. O., & Herrmann, L. 2020. Solid-state fermentation tech-nology and innovation for the production of agricultural and animal feed bioprod-ucts. Syst. Microbiol. Biomanufact. 1, 142–165. In.
Vargas Hernández, J., Coste, S., García Murillo, A., Carrillo Romo, F., & Kassiba, A. 2017. Effects of metal doping (Cu, Ag, Eu) on the electronic and optical behavior of nanostructured TiO2. Journal of Alloys and Compounds, 710, 355-363.
Vega-Gálvez, A., Uribe, E., Perez, M., Tabilo-Munizaga, G., Vergara, J., Garcia-Segovia, P., Lara, E., & Di Scala, K. 2011. Effect of high hydrostatic pressure pretreatment on drying kinetics, antioxidant activity, firmness and microstructure of Aloe vera (Aloe barbadensis Miller) gel. LWT - Food Science and Technology, 44(2), 384-391.
Vega, A., Ampuero, N., Díaz, L., & Lemus, R. 2005. El Aloe vera (Aloe barbadensis Miller) como componente de alimentos funcionales. Revista chilena de nutrición, 32(3), 208-214.
Vickers, N. J. 2017. Animal Communication: When I’m Calling You, Will You Answer Too? Current Biology, 27(14), R713-R715.
Vijayaraghavan, K., & Ashokkumar, T. 2017. Plant-mediated biosynthesis of metallic nanoparticles: A review of literature, factors affecting synthesis, characterization techniques and applications. Journal of Environmental Chemical Engineering, 5(5), 4866-488.
Vinson, J. A., Al Kharrat, H., & Andreoli, L. 2005. Effect of Aloe vera preparations on the human bioavailability of vitamins C and E. Phytomedicine, 12(10), 760-765.
Yuvasree, P., Nithya, K., & Neelakandeswari, N. (2013, 24-26 July 2013). Biosynthesis of silver nanoparticles from Aloe vera plant extract and its antimicrobial activity against multidrug resistant pathogens. International Conference on Advanced Nanomaterials & Emerging Engineering Technologies,
Zapata, P. J., Navarro, D., Guillén, F., Castillo, S., Martínez-Romero, D., Valero, D., & Serrano, M. 2013. Characterisation of gels from different Aloe spp. as antifungal treatment: Potential crops for industrial applications. Industrial Crops and Products, 42, 223-230.
