Salicylic acid an efficient organocatalyst for synthesis of coumarins
الموضوعات : International Journal of Heterocyclic Chemistry
Rushikesh Mane
1
(Post graduate center in Organic Chemistry and Department of Chemistry
Hutatma Rajguru Mahavidyalaya, Rajgurunagar, Pune-410505 India)
Pramod Kulkarnia
2
(Post graduate center in Organic Chemistry and Department of Chemistry
Hutatma Rajguru Mahavidyalaya, Rajgurunagar, Pune-410505 India)
الکلمات المفتاحية: phenol, Pechmann condensation, β-keto esters, Organocatalysis, Coumarins,
ملخص المقالة :
Various substituted coumarins were synthesized in high yield and purity by direct reaction of substituted phenol and β-keto esters in the presence of a catalytic amount of salicylic acid under solvent-free conditions. This method is simple, cost-effective, short reaction time, simple work-up procedure, and avoid the use of transition metals.
