Investigation into the regioisomeric composition of some fused tetrazoles

الموضوعات : International Journal of Heterocyclic Chemistry

Paria Nasehi ¹ , Omid Baravaye ² , Sanaz Hafezi Birgani ³ , Mohsen Nikpour ⁴

1 - Departmentof Chemistry, School of Sciences, Islamic Azad University, Ahvaz Branch, Ahvaz
2 - Departmentof Chemistry, School of Sciences, Islamic Azad University, Ahvaz Branch, Ahvaz
3 - Departmentof Chemistry, School of Sciences, Islamic Azad University, Ahvaz Branch, Ahvaz
4 - Departmentof Chemistry, School of Sciences, Islamic Azad University, Ahvaz Branch, Ahvaz

تاريخ الإرسال : 25 الأربعاء , شعبان, 1437 تاريخ التأكيد : 25 الأربعاء , شعبان, 1437 تاريخ الإصدار : 10 الثلاثاء , جمادى الثانية, 1433

الکلمات المفتاحية: 3, 7-chloro-1-phenylpyrimido[4, 5e][1, 4]thiadiazines, 7-hydrazinyl-1-phenylpyrimido[4, 5-e][1, 4]thiadiazin, 5H-tetrazolo[1&#039, , 5&#039, :1, 2]pyrimido[4, 4]thiadiazine, 9H-tetrazolo[5&#039, , 1&#039, :2, 3]pyrimido[4, 1HNMR study, diazotization, tetrazole-azide tautomerism,

ملخص المقالة :

Treatment of 7-chloro-1-phenylpyrimido[4,5-e][1,3,4]thiadiazines with hydrazine in boiling ethanol gave corresponding7-hydrazinyl derivatives. Diazotization of the latter compounds acheived a mixture of 5H-tetrazolo[1',5':1,2]pyrimido[4,5-e][1,3,4]thiadiazine and 9H-tetrazolo[5',1':2,3]pyrimido[4,5-e][1,3,4]thiadiazines. Ratio of these two group of products determined by 1HNMR studies and no significant preference was observed for their formation. Efforts for separation of the products were unsuccessful and its reason is discussed.