Different Geometry Design Structures of Tissue Scaffolds for Additive Manufacturing

الموضوعات :

amirhossein Ehsani ¹ (Department of Mechanical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran)
sadegh rahmati ² (Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran)
Mohammad Nikkhoo ³ (Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran)
Shahram Etemadi Haghighi ⁴ (Department of Mechanical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran)
Mohammad Haghpanahi ⁵ (Biomechanics Group, Department of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran)

تاريخ الإرسال : 17 الثلاثاء , ذو الحجة, 1442 تاريخ التأكيد : 14 الثلاثاء , صفر, 1443 تاريخ الإصدار : 26 الأربعاء , ربيع الثاني, 1443

الکلمات المفتاحية: Pore Geometry, Tissue Engineering, Finite Element Analysis, Additive Manufacturing, Cubic Scaffold, Mechanical strength,

ملخص المقالة :

The design and manufacturing cubic porous scaffolds are a considerable notion in tissue engineering (TE). From Additive manufacturing (AM) perspective, it has attained high appeal in the string of TE during the past decade. In the view of TE, the feasibility of manufacturing intricate porous scaffolds with high accuracy contrast to prominent producing methods has caused AM the outstanding option for manufacturing scaffold. From design perspective, porous scaffold structures play a crucial task in TE as scaffold design with an adequate geometries provide a route to required strength and porosity. The target of this paper is achieve of best geometry to become an optimum mechanical strength and porosity of TE scaffolds. Hence, the cubic geometry has been chosen for scaffold and Cube, Cylinder and Hexagonal prism geometries have been selected for pore of structures. In addition, for noticing the porosity effects, pore size has been chosen in three size, and a whole of nine scaffolds have been designed. Designed scaffolds were generated using Fused Deposition Modeling (FDM) 3D Printer and dimensional specifications of scaffolds were evaluated by comparing the designed scaffolds with Scanning Electron Microscope (SEM). The samples were subjected to mechanical compression test and the results were verified with the Finite Element Analysis (FEA). The results showed that firstly, as the porosity increases, the compressive strength and modulus of elasticity obviously decreased in all geometry pore scaffolds. Secondly, as the geometry changes in similar porosity, cubic pore scaffold achieved higher compressive strength and modulus of elasticity than cylinder and hexagonal prime. Experimental and FEM validated results proposed a privileged feasible pore geometry of cubic scaffold to be used in design and manufacturing of TE scaffolds.

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