شارک

عنوان URL للمقالة


رقم المقالة : JCHR-2108-1380 (R1) زيارة : 323 الصفحة: 597 - 607

10.22034/jchr.2021.1937630.1380

نوع المخطوط: ابحاث

Health Risk Assessment of Heavy Metals in Edible Mushrooms and their Effect on Anemia: A Review Study

الموضوعات :

Alireza Esmaeili 1 , Shabnam Shamaei 2 , Ebrahim Molaee Aghaee 3 , Zabih Nosrati Akhtar 4 , Seyede Fatemeh Hosseini 5 , Samira shokri 6

1 - Non-Communicable Disease Research Center, Ilam University of Medical Sciences, Ilam, Iran|Assistant Professor of Hematology and Oncology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
2 - Department of Chemistry, Khorramabad Branch, Islamic Azad University, Khorramabad, Iran
3 - Department of Environmental Health, Food Safety Division, Faculty of Public Health, Tehran University of Medical Sciences, Tehran, Iran
4 - Master of Veterinary Parasitology, Boroujerd Branch, Islamic Azad University, Boroujerd, Iran
5 - Department of Biology Faculty of Basic University of Mazandaran, Babolsar, Iran
6 - Department of Environmental Health, Food Safety Division, Faculty of Public Health, Tehran University of Medical Sciences, Tehran, Iran

تاريخ الإرسال : 01 الجمعة , ذو القعدة, 1442 تاريخ التأكيد : 25 الخميس , محرم, 1443 تاريخ الإصدار : 07 الخميس , جمادى الأولى, 1444

الکلمات المفتاحية: Mushroom, Risk Assessment, Anemia, Toxic, Heavy metal, Carcinogenic,

ملخص المقالة :

Anemia patients are more susceptible to environmental contaminations such as heavy metals. The present study aimed at risk assessment of heavy metals in edible mushrooms and Anemia.The databases searched in those articles were Google Scholar, SID, Scopus, PubMed, Science Direct, and ISI. Related human health risks were calculated using the target hazard quotient (THQ). THQ ratio of Cd, Cu, Fe, Pb, Cr, Ni, and Mn were 3×10−3, 2.31, 8.43×10 −1, 2.35, 2.92×10−1, 6.6×10− 2 and 1.96×10− 1 m m-1 respectively. The highest non-carcinogenic diseases risk for adults were found in Pb (2.35 m m-1) while the lowest value was observed in Cd (3×10− 3 m m-1). The risk of carcinogenicity of lead was at the level of acceptable (10−4 to 10−6 m m-1). There is no concern about the non-carcinogenic risk of consuming heavy metals in edible mushrooms, in Iran except Cu and Pb. In some countries, adults and children can be exposed to non-cancerous foods by eating mushrooms. And can aggravate anemia in the consumer.

المصادر:


  1. Ouzouni P.K., 2009. Nutritional value and metal content of wild edible mushrooms collected from West Macedonia and Epirus, Greece. Food Chemistry. 115(4), 1575-1580.
    2.
  2. Firenzuoli F., L. Gori L., Lombardo G., 2008. The medicinal mushroom Agaricus blazei murrill: review of literature and pharmaco-toxicological problems. Evidence-Based Complementary and Alternative Medicine. 5(1), 3-15.
    3.
  3. Kula I., 2011. Determination of mercury, cadmium, lead, zinc, selenium and iron by ICP-OES in mushroom samples from around thermal power plant in Muğla, Turkey. Bulletin of Environmental Contamination and Toxicology. 87(3), 276-281.
    4.
  4. Mendil D., 2004. Determination of trace elements on some wild edible mushroom samples from Kastamonu, Turkey. Food Chemistry. 88(2), 281-285.
    5.
  5. Isildak Ö., 2004. Analysis of heavy metals in some wild-grown edible mushrooms from the middle black sea region, Turkey. Food Chemistry. 86(4), 547-552.
    6.
  6. Liu Y., Fukuwatari Y., Okumura K., Takeda K., Ishibashi K.I. Furukawa M., Ohno N., Mori Ming Gao K., Motoi  M., 2008. Immunomodulating activity of Agaricus brasiliensis KA21 in mice and in human volunteers. Evidence-Based Complementary and Alternative Medicine. 5(2), 205-219.
    7.
  7. Manzi P., 1999. Mushrooms as a source of functional ingredients. Euro Food Chemistry 10. In Europien Conference on: Functional foods, A new challenge fort the food chemist, Budapest. 3.
    8.
  8. Alloway B.J., 2012. Heavy metals in soils: trace metals and metalloids in soils and their bioavailability. Environmental Pollution book series. 22, 4.
    9.
  9. Tchounwou P.B., Yedjou C.G., Patlolla A.K., Sutton D.J., 2012. Heavy metal toxicity and the environment. Molecular, Clinical and Environmental Toxicology. 133-164.
    10.
  10. Singh A., Kumar R., Sharma R., Agrawal M., Marshall F.M., 2010. Health risk assessment of heavy metals via dietary intake of foodstuffs from the wastewater irrigated site of a dry tropical area of India. Food and Chemical Toxicology. 48(2), 611-619.
    11.
  11. Marx J., Hockberger R., Walls R., 2013. Rosen's Emergency Medicine-Concepts and Clinical Practice E-Book: 2-Volume Set. 2013: Elsevier Health Sciences. 8-11.
    12.
  12. Fesharakinia A., 2014. The prevalence of iron deficiency and its anemia in 1-5 years old children and their mothers in Birjand City. Journal of Fasa University of Medical Sciences. 3(4), 325- 329.
    13.
  13. Turgut S., 2007. Interaction between anemia and blood levels of iron, zinc, copper, cadmium and lead in children. The Indian Journal of Pediatrics. 74(9), 827-830.
    14.
  14. Neoh K., 2017.Estimating prevalence of functional iron deficiency anaemia in advanced cancer. Supportive Care in Cancer. 25(4), 1209-1214.
    15.
  15. Eslami M., 2013. Importance of pre-pregnancy counseling in Iran: results from the high risk pregnancy survey 2012. International Journal of Health Policy and Management. 1(3), 213-215.
    16.
  16. Joint F., W.E.C.o.F. Additives, and W.H., 1990. Organization, Evaluation of certain food additives and contaminants: thirty-fifth report of the Joint FAO. 1990: World Health Organization.
    17.
  17. Cheraghi M., Lorestani B., Mardokh Rohani N., 2013.Evaluation of heavy metal concentration in compost, soil cover and button mushroom in Kurdistan greenhouses. Food Hygiene. 2(4 (8)), 81-96.
    18.
  18. Anbari M., 2011. Investigation of lead and Cadmium contents of cultivated edible mushrooms consumed in Tehran, 2011. Technology. 30, 8, 85-91.
    19.
  19. USEPA (US Environmental Protection Agency). 1992. Guidelines for exposure assessment. Available at http://www.epa.gov/ncea/pdfs/guidline.pdf.
    20.
  20. Institute of Standards and Industrial Research of Iran. Food and feed-maximum limit of heavy metals. Standard No. 12968. Tehran: Institute of Standards and Industrial Research of Iran, 2010.
    21.
  21. Shokrzadeh M., 2014. The Levels of Lead, Cadmium and Chromium in Edible Mushrooms in Sari. Journal of Mazandaran University of Medical Sciences. 24 (117), 165-172.
    22.
  22. Ardakani S., Jahangard A., 2017.Toxicological assessment of inorganic arsenic and zinc content in button mushrooms. Journal of Advances in Environmental Health Research. 5(4), 246-251.
    23.
  23. Khudabakhshi A., Sedehi Shakeri K., 2016. Determination of some heavy metals in edible fungi in Shahrekord. Journal of Shahrekord University of Medical Sciences.18(1), 3-9.
    24.
  24. Karami H., 2021. The Concentration and Probabilistic Health Risk of Potentially Toxic Elements (PTEs) in Edible Mushrooms (Wild and Cultivated) Samples Collected from Different Cities of Iran. Biological Trace Element Research. 199(1), 389-400.
    25.
  25. Kumari B., Atri N.S., 2014. Nutritional and nutraceutical potential of wild edible macrolepiotoid mushrooms of north India. International Journal of Pharmacy and Pharmaceutical Sciences. 6(2), 200-204.
    26.
  26. Sevindik M., Akata I., 2020. Antioxidant, oxidant potentials and element content of edible wild mushroom Helvella leucopus. Indian Journal of Natural Products and Resources (IJNPR)[Formerly Natural Product Radiance. 10(4), 266-271.
    27.
  27. Gast C., Jansen E., Bierling J., Haanstra L., 1988. Heavy metals in mushrooms and their relationship with soil characteristics. Chemosphere. 17(4)789-799.
    28.
  28. Isildak O., 2007. Bioaccumulation of heavy metals in some wild‐grown edible mushrooms. Analytical Letters. 40(6), 1099-1116.
    29.
  29. Zhu F., 2011. Assessment of heavy metals in some wild edible mushrooms collected from Yunnan Province, China. Environmental Monitoring and Assessment. 179(1), 191-199.
    30.
  30. Sesli E., Tuzen M., Soylak M., 2008. Evaluation of trace metal contents of some wild edible mushrooms from Black sea region, Turkey. Journal of Hazardous Materials. 160(2-3), 462- 467.
    31.
  31. Sarikurkcu C., 2011. Metal concentration of wild edible mushrooms in Soguksu National Park in Turkey. Food Chemistry. 128(3), 731-734.
    32.
  32. Lalotra P., 2016. Bioaccumulation of heavy metals in the sporocarps of some wild mushrooms. Curr. Res. Environ. Appl Mycol J Fungal Biol. 6, 159-165.
    33.
  33. Türkmen M., Budur D., 2018. Heavy metal contaminations in edible wild mushroom species from Turkey’s Black Sea region. Food Chemistry. 254, 256-259.
    34.
  34. Radulescu C., 2010. Studies concerning heavy metals bioaccumulation of wild edible mushrooms from industrial area by using spectrometric techniques. Bulletin of Environmental Contamination and Toxicology. 84(5), 641-646.
    35.

35.Árvay J., Tomáš J., Hauptvogl M., Kopernická M.,  Kováčik A., Bajčan D., Massányi P., Contamination of wild-grown edible mushrooms by heavy metals in a former mercury-mining area. Journal of Environmental Science and Health, Part B. 49(11), 815- 827.

  1. Bahadori M.B., kcu C.S., Yalcin O.U., Cengiz M., Gungor H., 2019. Metal concentration, phenolics profiling, and antioxidant activity of two wild edible Melanoleuca mushrooms (M. cognata and M. stridula). Microchemical Journal. 150, 104172-104173.
    2.
  2. Cvetkovic J.S., 2015. Elemental composition of wild edible mushrooms from Serbia. Analytical Letters. 48(13), 2107-2121.
    3.
  3. Durkan N., 2011. Concentrations of trace elements aluminum, boron, cobalt and tin in various wild edible mushroom species from Buyuk Menderes River Basin of Turkey by ICP-OES. Trace Elements and Electrolytes. 28(4), 242.
    4.
  4. Tsegay M.B., Asgedom A.G., Belay M.H., 2019. Content of major, minor and toxic elements of different edible mushrooms grown in Mekelle, Tigray, Northern Ethiopia. Cogent Food & Agriculture. 5(1), 13-19.
    5.
  5. Golalipour M.J., Roshandel D., Roshandel G.R., Ghafari S., Kalavi M., Kalavi K., 2007. Effect of lead intoxication and D-penicillamine treatment on hematological indices in rats. International Journal of Morphology. 25(4), 717-722.
    6.
  6. Gallagher C.M., Chen J.J., Kovach J.S., 2011. The relationship between body iron stores and blood and urine cadmium concentrations in US never-smoking, non-pregnant women aged 20–49 years. Environmental Research, 111(5), 702-707.
    7.
  7. Boudaghi H., Younesian M., Mahvi A.H., Mohammadi M.A., Dehghani M.H., Nazm ara Sh., 2011. Determination of arsenic, cadmium and lead in soil and groundwater and its relationship with chemical fertilizer in Ghaem shahr city (case study farm in Vahdat). Journal of Mazandaran UniversitY of Medical Sciences. 21(86), 21-29.
    8.
  8. Manouchehri A.A., Pirhadi, M., Parsaei, P., Alikord, M., Safian Boldaji H., 2021. A review of aflatoxin M1 in milk and dairy products and new procedure for evaluating aflatoxin M1. J Chem Health Risks. [In press].
    9.
  9. Pirhadi M., Shariatifar N., Bahmani M., Manouchehri A.A., 20121. Heavy metals in wheat grain and its impact on human health: A review. J Chem Health Risks. [In press].
    10.
  10. Farzan B., Shahsavari S., Abbaszadeh S., Teimouri H., 2019. Phytotherapy for seizure: An overview of the most important indigenous Iranian medicinal plants with anticonvulsant properties. Plant Science Today. 6(4), 367-372.
    11.
  11. Manouchehri A., Shakib P., Biglaryan F., Nazer M., Darvishi M., 2021. The most important medicinal plants affecting bee stings: A systematic review study. Uludag Aricilik Dergisi. 21(1), 91-103.
    12.
  12. Esmaeili A., Parsaei, P., Nazer, M.R., Bakhtiari R., Mirbehresi H., Safian Boldaji H., 20121. Phytotherapy in Burn Wound Healing: A Review of Native Iranian Medicinal Plants. J Chem Health Risks. [In press].
    13.
  13. Alizadeh M., Safarzadeh, A., Bahmani, M., Beyranvand, F., Rafieian-Kopaei, M., Abbaszadeh, S., 2018. Brucellosis: Pathophysiology and new promising treatments with medicinal plants and natural antioxidants. Asian Pacific J Trop Med. 11(11), 597-608.
    14.
  14. Abbaszadeh S., Andevari A.N., Koohpayeh, A., Naghdi, N., Alizadeh, M., Beyranvand, F., Harsej, Z., 2018. Folklore medicinal plants used in liver disease: A review. Int J Green Pharmacy.12(3), 463-472.
    15.
  15. Sedighi M., Sewell R.D.E., Nazari A., Abbaszadeh S., Cheraghi M., Amini A., Heydari Z., Rafieian-Kopaei M., 2019. A review on the most important medicinal plants effective in cardiac ischemia-reperfusion injury. Current Pharmaceutical Design. 25(3), 352-358.
    16.

51.Nouri A., Heidarian E., Amini-Khoei H., Abbaszadeh S., Basati G., 2019.  Quercetin through mitigation of inflammatory response and oxidative stress exerts protective effects in rat model of diclofenac-induced liver toxicity. J Pharmacy Pharmacog Res. 7(3), 200-212.

52.Abbasi N., Khalighi Z., Eftekhari Z.,  Bahmani M., 2020. Extraction and phytoanalysis of chemical compounds of Eucalyptus globulus leaf native to Dehloran, Ilam province, Iran by HS-SPME and GC-MS. Advances in Animal and Veterinary Sciences. 8(6), 647-652.

  1. Eftekhari Z., 2020. Garlic: A brief overview of its interaction with chemical drugs. Plant Biotechnol Persa. 2(2), 31-32
    2.
  2. Aidy A., Karimi E., Ghaneialvar H., Mohammadpour S., Abbasi N., 2020. Protective effect of Nectaroscordum tripedale extract and its bioactive component tetramethylpyrazine against acetaminophen-induced hepatotoxicity in rats. Advances in Traditional Medicine. 20(3), 471-477.
    3.
  3. Karimi E., Abbasi S., Abbasi N., 2019. Thymol polymeric nanoparticle synthesis and its effects on the toxicity of high glucose on OEC cells: Involvement of growth factors and integrin-linked kinase. Drug Design, Development and Therapy. 13, 2513-2532.
    4.

56.Abbasi N., Khosravi A., Aidy A., Shafiei M., 2016. Biphasic response to luteolin in MG-63 osteoblast-like cells under high glucose-induced oxidative stress. Iranian Journal of Medical Sciences. 41(2), 118-125.

سند

Sanad is a platform for managing Azad University publications

الروابط

المراكز ذات الصلة

دعامة

الصفحات الرسمية

حقوق هذا الموقع الإلكتروني مملوكة لنظام SANAD Press Management. © 1442-1446

الصفحة الرئيسية| دخول| معلومات عنا| اتصل بنا|
[English] [فارسی] [en] [fa]