Effect of Replacing Dietary FeSO4 with FeHPO4 Nanoparticles on Growth Performance, Carcass Characteristics and Tissue Iron Content in Broilers
الموضوعات :
M.A. Behroozlak
1
(Department of Animal Science, Faculty of Agriculture, Urmia University, Urmia, Iran)
م. دانشیار
2
(Department of Animal Science, Faculty of Agriculture, Urmia University, Urmia, Iran)
پ. فرهومند
3
(Department of Animal Science, Faculty of Agriculture, Urmia University, Urmia, Iran)
ع. نیکو
4
(Department of Organic Chemistry, Faculty of Chemistry, Urmia University, Urmia, Iran)
الکلمات المفتاحية: performance, broiler chickens, FeSO4, iron content, FeHPO4 nanoparticles,
ملخص المقالة :
A study was conducted to compare the effects of iron hydrogen phosphate nanoparticles (FeHPO4) with iron sulfate (FeSO4-7H2O) on growth performance, carcass characteristics and mineral content of breast muscle in broiler chickens. A total of 200 one-day-old male Ross 308 broiler chicks were assigned randomly into four dietary groups with five replications of ten chicks per replicate. The basal diet (BD) included corn-soybean meal with 87.40, 85.13 and 82.24 mg Fe/kg diet in starter, grower and finisher feeding phases, respectively. Four dietary groups consisted of: group 1) BD + 80 mg/kg FeSO4, as control group; group 2) BD + 6.4 mg/kg FeHPO4 nanoparticles (FNPs); group 3) BD + 3.2 mg/kg FNPs; and group 4) BD + 1.6 mg/kg FNPs were provided during 1-42 d of age. The results showed that dietary groups did not significantly (P>0.05) affect the average daily feed intake (ADFI), average daily weight gain (ADWG), feed conversion ratio (FCR), mortality rate, and European production efficiency factor (EPEF). Adding FNPs in dietary group 2 significantly (P= 0.04) reduced relative weight of abdominal fat compared to control group. Furthermore, there were cubic (P=0.05) and quadratic (P=0.02) responses to the addition of FNPs in dietary group 3 on carcass yield and relative weight of liver, respectively. Compared with birds fed the diet supplemented with 80 mg FeSO4/kg, birds fed supplemental FNPs in groups 2 and 3 had significantly increased Fe and Cu content in the breast muscle (P<0.05). There was no differences in Zn content of breast muscle among the dietary groups (P>0.05). This study concluded that, replacing FeSO4 with FNPs had no significant effect on growth performance, but it could significantly increase the iron content of breast muscle.
Akbari Moghaddam Kakhki R., Bakhshalinejad R., Hassanabadi A. and Ferket P. (2016). Effects of dietary organic zinc and α-tocopheryl acetate supplements on growth performance, meat quality, tissues minerals, and α-tocopherol deposition in broiler chickens. Poult. Sci. 96, 1257-1267.
Akter M., Iji P.A. and Graham H. (2017). Increased iron level in phytase-supplemented diets reduces performance and nutrient utilisation in broiler chickens. Br. Poult. Sci. 58, 409-417.
Amine E.K., Hegsted D.M. and Neff R. (1972). Biological estimation of available iron using chicks or rats. J. Agric. Food Chem. 20, 246-251.
AOAC. (1994). Official Methods of Analysis. 12th Ed. Association of Official Analytical Chemists, Arlington, Washington, DC., USA.
Arredondo M., Munoz P., Mura C. and Nunez M.T. (2003). DMT1, a physiologically relevant apical Cu+1 transporter of intestinal cells. Am. J. Physiol. 284, 1525-1530.
Aviagen. (2014). Ross 308: Broiler Nutrition Specifications. Huntsville, Alabama, USA.
Bano F., Baber M., Ali A., Shah Z. and Muhammad S.A. (2017). Biosynthesis, characterization, and biological activities of iron nanoparticles using Sesamum indicum seeds extract. Pharmacogn. Mag. 13, 33-36.
Buzala M., Slomka A. and Janicki B. (2016). Heme iron in meat as the main source of iron in the human diet, a review. J. Elementol. 21, 303-314.
Chen J., Tan B., Karteris E., Zervou S., Digby J., Hillhouse E.W., Vatish M. and Randeva H.S. (2006). Secretion of adiponectin by human placenta: differential modulation of adiponectin and its receptors by cytokines. Diabetologia. 49, 1292-302.
Collins J.F., Prohaska J.R. and Knutson M.D. (2010). Metabolic crossroads of iron and copper. Nutr. Rev. 68, 133-147.
Diez J.J. and Iglesias P. (2003). The role of the novel adipocyte-derived hormone adiponectin in human disease. European J. Endocrinol. 148, 293-300.
Fisher A. (1984). Fat deposition in broilers. Pp. 437-470 in Fats in Animal Nutrition. J. Wiseman, Ed. Butterworths, London, United Kingdom.
Gabrielsen J.S., Gao Y., Simcox J.A., Huang J., Thorup, D., Jones D., Cooksey R.C., Gabrielsen D., Adams T.D., Hunt S.C., Hopkins P.N., Cefalu W.T. and McClain D.A. (2012). Adipocyte iron regulates adiponectin and insulin sensitivity. J. Clin. Invest. 122, 3529-3540.
Garcia O.P., Long K.Z. and Rosado J.L. (2009). Impact of micronutrient deficiencies on obesity. Nutr. Rev. 67, 559-572.
Garcia O.P., Ronquillo D., del Carmen Caamaño M., Martínez G., Camacho M., López V. and Rosado J.L. (2013). Zinc, iron and vitamins A, C and E are associated with obesity, inflammation, lipid profile and insulin resistance in Mexican school-aged children. Nutrients. 5, 5012-5030.
Garcia-Diaz D.F., Campion J., Milagro F.I., Boque N., Moreno-Aliaga M.J. and Martinez J.A. (2010). Vitamin C inhibits leptin secretion and some glucose/lipid metabolic pathways in primary rat adipocytes. J. Mol. Endocrinol. 45, 33-43.
Gunshin H., Mackenzie B., Berger U.V., Gunshin Y., Romero M.F., Boron W.F., Nussberger S., Gollan J.L. and Hediger M.A. (1997). Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature. 388, 482-488.
Hermier D. (1997). Lipoprotein metabolism and fattening in poultry. J. Nutr. 127, 805-808.
Huang S., Wang L., Liu L., Hou Y. and Li L. (2015). Nanotechnology in agriculture, livestock, and aquaculture in China. A review. Agron. Sustain. Dev. 35, 369-400.
Hussain N., Jaitley V. and Florence A.T. (2001). Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics. Adv. Drug Deliv. Rev. 50, 107-142.
Jani P., Halbert G.W., Langridge J. and Florence A.T. (1990). Nanoparticle uptake by the rat gastrointestinal mucosa: Quantitation and particle size dependency. Pharmacology. 42, 821-826.
Kwiecien M., Samolinska W. and Bujanowicz-Haras B. (2015). Effects of iron-glycine chelate on growth, carcass characteristic, liver mineral concentrations and haematological and biochemical blood parameters in broilers. J. Anim. Physiol. Anim. Nutr. 99, 1184-1196.
Lee J.H., Ju J.E., Kim B.I., Pak P.J., Choi E.K., Lee H.S. and Chung N. (2014). Rod shaped iron oxide nanoparticles are more toxic than sphere-shaped nanoparticles to murine macrophage cells. Environ. Toxicol. Chem. 33, 2759-2766.
Ma X., Liao X., Lu L., Li S., Zhang L. and Luo X. (2016). Determination of dietary iron requirements by full expression of iron-containing enzymes in various tissues of broilers. J. Nutr. 146, 2267-2273.
Mirghelenj S.A., Golian A., Behroozlak M.A. and Moradi S. (2016). Effects of different fat sources in finisher diet of broiler chickens on performance, fat deposition and blood metabolites. Iranian J. Appl. Anim. Sci. 6, 165-172.
Miroshnikova E., Arinzhanov A., Kilyakova Y., Sizova E. and Miroshnikov S. (2015). Antagonist metal alloy nanoparticles of iron and cobalt: impact on trace element metabolism in carp and chicken. Hum. Vet. Med. Bioflux. 7, 253-259.
Moon Y.S., Latasa M.J. and Kim K.H. (2000). Two regions are required for nutritional and insulin regulation of the fatty acid synthase promoter in transgenic mice. J. Biol. Chem. 14, 10121-10127.
Motzok I., Pennell M.D., Davies M.I. and Ross H.U. (1975). Effect of particle size on the biological availability of reduced iron. J. Assoc. Off. Anal. Chem. 58, 99-103.
Nedvidkova J., Smitka K., Kopsky V. and Hainer V. (2005). Adiponectin, an adipocyte-derived protein. Physiol. Res. 54, 133-140.
Nikonov I.N., Yu G., Folmanisb G.E., Folmanisb L.V., Kovalenkob G., Yu Lapteva I., Egorovc A., Fisininc V.I. and Tananaevd I.G. (2011). Iron nanoparticles as a food additive for poultry. Doklady Biol. Sci. 440, 328-331.
NRC. (1994). Nutrient Requirements of Poultry, 9th Rev. Ed. National Academy Press, Washington, DC., USA.
Oliveira F., Rocha S. and Fernandes R. (2014). Iron metabolism: From health to disease. J. Clin. Lab. Anal. 28, 210-218.
Rahi A., Sattarahmady N. and Heli H. (2014). Toxicity of nanomaterials-physicochemical effects. Austin. J. Nanomed. Nanotechnol. 2, 1034-1046.
Rahmatollah D., Farzinpour A., Vaziry A. and Sadeghi G. (2018). Effect of replacing dietary FeSO4 with cysteine coated Fe3O4 nanoparticles on quails. Italian J. Anim. Sci. 17, 121-127.
Rohner F., Ernst F.O., Arnold M., Hilbe M., Biebinger R., Ehrensperger F., Pratsinis S.E., Langhans W., Hurrell R.F. and Zimmermann M.B. (2007). Synthesis, characterization, and bioavailability in rats of ferric phosphate nanoparticles. J. Nutr. 137, 614-619.
Saki A.A., Abbasinezhad M. and Rafati A.A. (2014). Iron nanoparticles and methionine hydroxy analogue chelate in ovo feeding of broiler chickens. Int. J. Nanosci. Nanotechnol. 10, 187-196.
SAS Institute. (2009). SAS®/STAT Software, Release 9.2. SAS Institute, Inc., Cary, NC. USA.
Seo S.H., Lee H.K., Ahn H.J. and Paik I.K. (2008). The effect of level and period of Fe-methionine chelate supplementation on the iron content of broiler meat. Asian-Australasian J. Anim. Sci. 21, 1501-1505.
Shinde D.L., Ingale S.L., Kim J.Y., Pak S.I. and Chae B.I. (2011). Efficiency of inorganic and organic iron sources under iron depleted conditions in broilers. Br. Poult. Sci. 52, 578-583.
Suliburska J., Bogdanski P., Pupek-Musialik D. and Krejpcio Z. (2011). Dietary intake and serum and hair concentrations of minerals and their relationship with serum lipids and glucose levels in hypertensive and obese patients with insulin resistance. Biol. Trace Elem. Res. 139, 137-150.
Ukkola O. and Santaniemi M. (2002). Adiponectin: a link between excess adiposity and associated comorbidities? J. Mol. Med. 80, 696-702.
Underwood E.J. (1977). Trace Elements in Human and Animal Nutrition. Academic Press, New York.
Verma R.S., Motzok I., Chen S.S., Rasper J. and Ross H.U. (1977). Effect of storage in flour and of particle size on the bioavailability of elemental iron powders for rats and humans. J. Assoc. Off. Anal. Chem. 60, 759-765.
Wang L., Hu C. and Shao L. (2017). The antimicrobial activity of nanoparticles: present situation and prospects for the future. Int. J. Nanomed. 12, 1227-1249.
Williams D.B., Wan Z., Frier B.C., Bell R.C., Field C.J. and Wright D.C. (2012). Dietary supplementation with vitamin E and C attenuates dexamethasone-induced glucose intolerance in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 302, 49-58.
Yausheva E., Miroshnikov S. and Sizova S. (2018). Intestinal microbiome of broiler chickens after use of nanoparticles and metal salts. Environ. Sci. Pollut. Res. Int. 25, 18109-18120.
Zavala G., Long K.Z., Garcia O.P., Caamano M.D., Aguilar T., Salgado L.M. and Rosado J.L. (2012). Specific micronutrient concentrations are associated with inflammatory cytokines in a rural population of Mexican women with a high prevalence of obesity. Br. J. Nutr. 109, 686-694.
Zerehdaran A., Vereijken A.L.J., Van Arendok J.A.M. and Van der Waaij E.H. (2004). Estimation of genetic parameters for fat deposition and carcass traits in broilers. Poult. Sci. 83, 521-525.
Zimmermann M.B. and Hilty F.M. (2011). Nano-compounds of iron and zinc: their potential in nutrition. Nanoscale. 3, 2390-2398.
