The Effect of in ovo Injection of Aromatase Inhibitors on the Performance of Broilers
الموضوعات :ت. مکرمی 1 , ب. نویدشاد 2 , ن. هدایت ایوریق 3 , ف. میرزائی آقجه قشلاق 4
1 - Department of Animal Science, University of Mohaghegh Ardabili, Ardabil, Iran
2 - Department of Animal Science, University of Mohaghegh Ardabili, Ardabil, Iran
3 - Department of Animal Science, University of Mohaghegh Ardabili, Ardabil, Iran
4 - Department of Animal Science, University of Mohaghegh Ardabili, Ardabil, Iran
الکلمات المفتاحية: broiler chickens, Aromatase inhibitors, fadrozole hydrochloride, mushroom extract, nettle extract, sexual differentiation,
ملخص المقالة :
Change in sex ratios for broiler chickens, has many economic benefits of the poultry industry. The gonads in chick embryo at an early stage have the potential to convert to both sexes (male and female). Sexual differentiation is due to aromatase expression in the left gonad in 5-6 days of the embryonic period and the production of estrogen from testosterone. Administration of aromatase inhibitors prevents the synthesis of estrogen in genetically female birds and produce males with female genotype. In this study, the effects of in ovo injection of 0.1 mg mushroom extract, nettle extract and fadrozole hydrochloride as aromatase inhibitors on the fifth day of incubation period on hatchability, embryo mortality and performance of hatching chicks were examined. The results of this experiment showed that there were no significant differences in hatchability, embryo mortality during incubation and the weight of hatching chicks. Daily feed intake and body weight gain in chickens hatched from mushroom extract and fadrozole hydrochloride groups were higher than the two other groups (p <0.05). Also, in ovo injection of a mushroom extract, nettle extract or fadrozole hydrochloride had no effect on the dressing percentage and internal organ weights.
Abousaad S., Lassiter K., Piekarski A., Chary P., Striplin K., Christensen K., Bielke L.R., Hargis B.M., Dridi S. and Bottje W.G. (2017). Effect of in ovo feeding of dextrin-iodinated casein in broilers: II. Hatch window and growth performance. Poult. sci. 96, 1478-1484.
Aviagen. (2014). Ross 308: Broiler Nutrition Specification. Aviagen Ltd., Newbridge, United Kingdom.
Azwanida N.N. (2015). A Review on the extraction methods use in medicinal plants, principle, strength and limitation. J. Med. Aroma Plants. 4, 196-201.
Broadbent L.A., Wilson B.J. and Fisher C. (1981). The composition of the broiler chicken at 56 days of age: Output, components and chemical composition. British Poult. Sci. 22, 385-290.
Burke W.H. (1992). Sex differences in incubation length and hatching weights of broiler chicks. J. Poult. Sci. 71, 1933-1938.
Burke W.H. and Henry M.H. (1999). The effects of in ovo administration of testosterone or an antiandrogen on growth of chick embryos and embryonic muscle characteristics. Poult. Sci. 78, 1 006-1013.
Chaurasia N. and Wichtl M. (1987). Flavonoglycosides from Urtica dioica. J. Planta Med. 53, 432-434.
Chen S., Oh S., Phuny S., Hur G., Jingye L., Lingkwok S., Gayle E., Belury M., Adams L. and Dudley W. (2006). Anti-aromatase activity of phytochemicals in White Buttom Mushrooms (Agaricus bisporus). J. Cancer Res. 66, 24-32.
Clinton M. (1998). Sex determination and gonadal development: A bird’s eye view. J. Exp. Zool. 281, 457-465.
Engku A. (1984). Carcass yield of broilers. MARDI Res Bull. 12, 107-115.
Engku A. and Noraziah M. (2000). Straight-run vs sex-segregated production of broilers. Pp. 129-130 in Proc. 22nd Malaysian Soc. Anim. Prod. Ann. Conf., Kota Kinabalu, Malaysia.
Gholami J., Qotbi A.A.A., Seidavi A.R., Meluzzi A., Tavaniello S. and Maiorano G. (2015). Effects of in ovo administration of betaine and choline on atchability results, growth and carcass characteristics and immune response of broiler chickens. Italian J. Anim. Sci. 14, 187-192.
Grey T., Robinson D. and Jones J.M. (1982). Effect of age and sex on the eviscerated yield, muscle and edible offal of a commercial broiler strain. British Poult. Sci. 23, 289-298.
Grove 1.F. (1981). Volatile compounds from the mycelium of the mushroom Agaricus bisporus. J. Phytochem. 20, 2021-2022.
Henrry M.H. and Burke W.H. (1998). Sexual dimorphism in broiler chicks embryos and embryonic muscle development in late incubation. Poult. Sci. 77, 728-736.
Laseinde E.A. and Oluyemi J.A. (1994). Effect of sex separation at the Finisher phase on the comparative growth performance, carcass characteristics and breast muscle development between male and female broiler chicken. Nigerian J. Anim. Prod. 21, 11-18.
Mafi M. (2012). Manipulation of chicken sex differentiation using in ovo injection of Stinging Nettle (Urtica dioica) root extract. MS Thesis. Giulan Univ., Rasht, Iran.
Marks H. (1985). Sexual dimorphism in early feed and water intake of broilers. J. Poult. Sci. 64, 425-428.
Marks H.L. (1986). The role of water intake on sexualdimorphism for early growth of broilers. J. Poult. Sci. 65, 433-435.
Marks H.L. (1987). Sexual dimorphism in broilers following periods of equal water and feed intake. J. Poult. Sci. 66, 381-389.
Matsushita S., Yamashita J., Iwasa T., Tomita T. and Ikeda M. (2006). Effects of in ovo exposure to imazalil and atrazine on sexual differentiation in chick gonads. J. Poult. Sci. 85, 1641-1647.
Merkley J., Weinland B., Malone G. and Chaloupka G. (1980). Evaluation of five commercial broiler crosses. 2. Eviscerated yield and component parts. Poult. Sci. 59, 1755-1760.
Mohammadrezaei M., Toghyani M., Eghbalsaied S., Gheisari A. and Esmaeili M. (2012). Growth performance and sex differentiation in broiler chickens submitted to in ovo injection of fadrozole and insulin-like growth factor I. Pp. 1039-1042 in Proc. Nutr. Feed Technol. Conf., which city??? Brazil.
Mottaghitalab M. and Razani K. (2005). Egg treatment with anti-aromatase: Effects on the chicks male: Female ratio, and their economic performance. Iranian J. Agric. Sci. 36, 375-383.
Pender C.M., Kim S., Potter T.D., Ritzi M.M., Young M. and Dalloul R.A. (2017). In ovo supplementation of probiotics and its effects on performance and immune-related gene expression in broiler chicks. Poult. Sci. 96, 1052-1062.
SAS Institute. (2002). SAS®/STAT Software, Release 9.3. SAS Institute, Inc., Cary, NC. USA.
Shahin K., Ibrahim S. and Elfaham A. (1996). The effects of breed and sex on carcass composition and tissue distribution of chickens. Indian J. Anim. Sci. 66, 504-510.
Shimada K. (1998). Gene expression of steroidogenic enzymes in chicken embryonic gonads. J. Exp. Zool. 281, 450-456.
Shimada K. and Saito N. (2000). Molecular mechanisms of sex determination and sex differentiation. Japanese Poult. Sci. 37, 3-11.
Sumpter J.P. and Fostier A. (1996). Effects offlavonoids on aromatase activity an in vitro study. J. Steroid Biochem. Mol. Biol. 57, 215-223.
Yoshida K., Shimada K. and Saito N. (1996). Expression of P450 (17α) hydroxylase and P450 aromatase genes in the chicken gonad before and after sexual differentiation. Gen. Comp. Endocrinol. 102, 233-240.
Verapeen D.S. and Driver M.F. (2000). Separate sex growing of Ross 208 Broilers and effects on broiler performance and carcass quality. Sci. Technol. Res. J. 4, 145-152.