Green synthesis of morpholine-2-thione by multicomponent reaction of aziridines

الموضوعات : Iranian Journal of Organic Chemistry

Narges Ghasemi ¹ , Samaneh sadat Sharifi ²

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تاريخ الإرسال : 02 الأحد , ربيع الأول, 1445 تاريخ التأكيد : 02 الأحد , ربيع الأول, 1445 تاريخ الإصدار : 14 الثلاثاء , محرم, 1445

الکلمات المفتاحية: multi component reaction, Aziridin, Carbone disulfide, Nitro methane,

ملخص المقالة :

A series of substituted morpholine-2-thione derivatives were synthesized via one-pot multicomponent reactions of nitromethane, carbon disulfide and aziridine in the presence of Et3N under solvent-free conditions. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.