A Simple and one-pot synthesis of imintriazole derivatives under Solvent-free conditions
الموضوعات : Iranian Journal of Organic Chemistry
Narges Ghasemi
1
()
Parvaneh Firoozi Khanghah
2
()
Mahboubeh Ghasemian Dazmiri
3
()
الکلمات المفتاحية: Solvent-free, One-pot reaction, Acid chlorides, Hydrazonoyl chloride, 3-amino-2-butanone,
ملخص المقالة :
An efficient synthesis of iminetriazole derivatives is described via an one-pot reaction between acid chlorides, 3-amino-2-butanone, primary amines and hydrazonoyl chloride under solvent-free conditions at room temperature in good yields. Also, the antimicrobial activity of some synthesized compounds proved by employing the disk diffusion test on Gram-positive and Gram-negative bacteria. This procedure has some benefits such as short reaction time, product with excellent yields, simple catalyst and products separation.
