Hypericum perforatum L. (Hypericaceae): Cultivation, diversity of biochemical composition, antimicrobial activities, active biomolecules and action mode-A review
Subject Areas : Medicinal and Herbal Plants
Hajar Afqir
1
*
,
Saadia Belmalha
2
,
Jihane Laarifi
3
,
Ayoub Farihi
4
,
Soumaya Baataoui
5
,
Brahim Bourkhiss
6
,
Hassane Tahiri
7
,
Mohammed Ouhssine
8
1 - Laboratory of Natural Resources and Sustainable Development, Faculty of Science, Ibn Tofail University - Kenitra, Kingdom of Morocco
2 - Department of Plant and Environment Protection, National School of Agriculture, BP S/40 50 000 Meknes-Maroc
3 - Laboratory of Natural Resources and Sustainable Development, Faculty of Science, Ibn Tofail University - Kenitra, Kingdom of Morocco
4 - Laboratory of Biology and Health, Biology Department, Ibn Tofail University, Faculty of Sciences, Morocco
5 - Laboratory of Natural Resources and Sustainable Development, Faculty of Science, Ibn Tofail University - Kenitra, Kingdom of Morocco
6 - Laboratory of Animal Plant Production and Agro-Industry, Department of Biology, Faculty of Sciences, Ibn Tofail University, B.P. 133, Kenitra 14000, Morocco
7 - Faculty of Science, Department of Biology, Ibn Tofail University, 14000, Kenitra, Morocco
8 - Laboratory of Natural Resources and Sustainable Development, Faculty of Science, Ibn Tofail University - Kenitra, Kingdom of Morocco
Keywords: Antimicrobial activities, Bioactive compounds, Essential oils, Hypericum perforatum L., Hypericaceae, Mechanism, Phytochemical constituents.,
Abstract :
This study analyses the knowledge on the cultivation, diversity, and variation of phytochemical constituents of essential oils and crude extracts from Hypericum perforatum. Equally, we presented a detailed discussion of the antimicrobial activities against pathogens and viruses, and the implicated biomolecules. A complete and organized literature search was carried out in the basic databases. According to the reviewed papers, Hypericum perforatum contains considerable amounts of chemical constituents, including phenolic, flavonoid, and terpene compounds, which are diverse and variable depending on the geography of plants, parts used, and extraction methods. These chemical constituents demonstrated serious inhibitory effects against fungi, bacteria, and viruses.
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