Epigallocatechin Gallate, a Unique Natural Compound with Tremendous Health Benefits
Subject Areas : Research On Crop Ecophysiology
Keywords: tea, Key words: Natural Compounds, Caner, Epigallocatechin,
Abstract :
Epigallocatechin Gallate, a Unique Natural Compound with Tremendous Health Benefits Wenli Sun1, Mohamad Hesam Shahrajabian1, and Qi Cheng1,2* 1Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China 2College of Life Sciences, Hebei Agricultural University, Baoding, Hebei, 071000, China; Global Alliance of HeBAU-CLS&HeQiS for BioAl-Manufacturing, Baoding, Hebei 071000, China. *Corresponding author E-mail: chengqi@caas.cn; hesamshahrajabian@gmail.com; Received: 10 Agust 2018 Accepted: 10 January 2019 Abstract Epigallocatechin gallate is a tea catechin. It is predominatly found in tea (green, white, oolong and black teas), fruits (cranberries, strawberries, blackberries, kiwis, cherries, pears, peaches, apples and avocados), and nuts (pecans, pistachios, and hazelnuts). Catechins may be further categorized into a larger group of plant compounds known as polyphenols. Epicatechin, epigallocateching and epicatechin 3-gallate also offer similar benefits. The most important pharmacological activities of EGCG are antineoplastic, HIV infection, hypertension and associated complications, type II diabetes mellitus, its usage as cardioprotective, hepatoprotective, nephroprotective, and its application in Alzheimer, Parkinson, and Osteoporosis. Its importance in cancer treatment is because of natural origin, safety, and low cost, but the main problem is its low bioavailability with various major limitations in EGCG studies. Key words: Natural Compounds, Caner, Tea, Epigallocatechin.