مقایسه تاثیر تمرینات مقاومتی، استقامتی و ترکیبی بر بیان ژن رزیستین دربافت‌های ماهیچه دست و پای موش های نر نژاد ویستار
محورهای موضوعی : نشانگر های زیستی پلاسمافاطمه حاجی قربانی زاده 1 , طاهره باقرپور 2 , نعمت اله نعمتی 3
1 - دانشجو ی دکتری فیزیولوژی ورزشی ، گروه تربیت بدنی ، واحد دامغان ، دانشگاه آزاد اسلامی ، دامغان ، ایران.
2 - استادیار گروه تربیت بدنی ، واحد دامغان ، دانشگاه آزاد اسلامی ، دامغان ، ایران
3 - دانشیار گروه تربیت بدنی ، واحد دامغان ، دانشگاه آزاد اسلامی ، دامغان ، ایران.
کلید واژه: رزیستین, تمرین ترکیبی, تمرین استقامتی , تمرین مقاومتی,
چکیده مقاله :
زمینه و هدف: رزیستین آدیپوکاینی است که توسط بافت‌های مختلف بدن ترشح می‌شود. این آدیپوکاین نقش مهمی در متابولیسم قند و لیپیدها ایفا می‌کند. مطالعه حاضر با هدف بررسی تأثیر تمرینات استقامتی، مقاومتی و ترکیبی بر سطح بیان ژن آدیپونکاین در ماهیچه‌های دست و پای موش‌های صحرایی نر نژاد ویستار انجام شد.
مواد و روش‌ها: در این مطالعه تجربی، 40 سر موش صحرایی نر سالم نژاد ویستار به چهار گروه ده‌تایی کنترل، تمرین مقاومتی، تمرین استقامتی و ترکیبی تقسیم شدند. هر گروه به مدت 8 هفته تمرین‌های مختص خود را انجام دادند. در نهایت، ماهیچه‌های دست و پا برای اندازه‌گیری بیان ژن رزیستین مورد بررسی قرار گرفتند. برای مقایسه گروه‌ها با هم، از آزمون تحلیل واریانس یک طرفه و برای مقایسه درون گروهی از آزمون تی زوجی استفاده شد.
نتایج: این مطالعه نشان داد که تمرینات ورزشی مختلف می‌توانند سطح بیان ژن رزیستین را در عضلات دست و پا نسبت به گروه کنترل افزایش دهند (001/0>P). همچنین، گروه‌های مورد مداخله در مقایسه با یکدیگر سطوح مختلفی از ژن رزیستین را بیان کردند، به طوری که تمرین ترکیبی بیشترین تاثیر را در کاهش بیان ژن رزیستین در مقایسه با تمرین‌های مقاومتی و استقامتی در عضله کند انقباض پا داشت (001/0>P).
نتیجه گیری: تمرین ورزشی ترکیبی، تمرین مقاومتی و تمرین استقامتی می‌توانند سطح بیان ژن رزیستین را در عضلات دست و پا نسبت به گروه کنترل کاهش دهند.
Background & Aim: Resistin is an adipokine secreted by adipocytes, but it can also be produced by other organs. This adipokine is crucial for glucose and lipid metabolism. The study aimed to explore the impact of endurance, resistance, and combined exercises on adiponkine gene expression in the hand and leg muscles of male Wistar rats.
Materials & Methods: In this experimental study, 40 healthy male Wistar rats were divided into four groups: control, resistance training, endurance training, and combined. Each group conducted their respective exercises for 8 weeks. Subsequently, hand and foot muscles were analyzed to measure resistin gene expression. The groups were compared using a one-way analysis of variance test, and intra-group comparisons were made using paired t-tests.
Results: The study's findings indicate that different sports exercises can elevate the expression of the resistin gene in hand and foot muscles compared to the control group (P <0.001). Furthermore, the intervention groups exhibited varying levels of resistin gene expression relative to each other, with concurrent training (0.02 ± 0.12) having the most significant impact on resistin gene expression compared to resistance training (0.04 ± 0.21) and endurance (0.04 ± 0.50) in slow twitch muscle of leg (P<0.001).
Conclusion: Concurrent trainings, resistance training, and endurance training can mitigate the expression level of the resistin compared to the control group.
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