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        1 - The effects of glutamine on serum LDH and CK in rats following a session of resistance activity
        Shima Ebadi Ardeshir Zafari
        Muscle pain after resistance activities, which occurs due to the destruction of sarcolema, increases the serum levels of LDH and CK enzymes as indicators of muscle damage. The results have shown that the use of food supplements such as glutamine can be useful in reducin More
        Muscle pain after resistance activities, which occurs due to the destruction of sarcolema, increases the serum levels of LDH and CK enzymes as indicators of muscle damage. The results have shown that the use of food supplements such as glutamine can be useful in reducing the serum indicators of muscle damage. The aim of the present study is to determine the effect of glutamine supplementation on serum indicators of muscle damage, including the serum levels of LDH and CK enzymes following a session of resistance activity. The present experimental study was carried out using an animal model in the form of a 3 group’s research design with a control group. To this end, 30 six-week-old adult male Wistar rats were kept under controlled conditions for 2 weeks and were then divided into three equal groups, including control, and resistance activity with/ without glutamine supplementation. The glutamine supplementation group received the prepared emulsion by gavage of 200 mg/kg of body weight. After five days, both experimental groups participated in a session of resistance activity (namely, climbing a smooth ramp with one and a half meters height and a 85° decline) with 4 sets, 5 repetitions, 30 seconds of rest between repetitions and 2 minutes of rest between sets. The initial load was considered equal to 50% of the rats' body weight. One-way analysis of variance and Bonferroni's post hoc test were used at a significance level of p ≥ 0.05. The levels of CK and LDH enzymes were different in groups. A five-day glutamine supplementation before performing a session of resistance activity can cause a lower increase in the serum levels of CK and LDH enzymes as serum indicators of muscle damage, which indicates the protective effect of glutamine in maintaining the integrity and structure of cell membrane. Manuscript profile
      • Open Access Article

        2 - The effect of eight weeks of aerobic training and Anethum herbal supplementation on lipid risk factors for cardiovascular disease in inactive obese men
        Ardeshir Zafari Taher Jalili
        Introduction:Studies show that the effects of different types of physical activity vary in various intensities and periods on body composition, lipid profile, and liver enzymes in men and women with varying levels of age, fitness, and health. Anethum herbal supplement c More
        Introduction:Studies show that the effects of different types of physical activity vary in various intensities and periods on body composition, lipid profile, and liver enzymes in men and women with varying levels of age, fitness, and health. Anethum herbal supplement can reduce cholesterol and triglycerides and help prevent and treat atherosclerosis. The effects of Anethum in interaction with exercise on blood lipids, body composition, and liver enzymes are unclear.Material & Methods:28 healthy and inactive male obese volunteers (age 20-30 years old) were randomly divided into four groups: Training, Anethum, Training+Anethum, and Control group. Independent variables included performing eight weeks of aerobic training and taking 650 mg of Anethum tablets for eight weeks, three times a day after meals. Dependent variables included lipid profile factors, body composition, and serum levels of liver enzymes. The intensity of aerobic training was set at 50 - 75% Vo2max using the HRR method to observe the principle of increasing overload. The main stage of training consisted of 45 minutes of aerobic activities. Paired samples t-test, one-way ANOVA, and Tukey's post hoc test were used to determine the within-groups and between-groups differences, respectively, at a significance level of 5%.Results: Performing eight weeks of aerobic training combined with Anethum herbal supplementation reduces LDL_c, TC, TG, BMI, WHR, ALT, ALP, and AST in the fasting state of inactive obese men(P<0.05). These variables' reduction rate was more significant in all intervention groups than in the control group. However, the groups did not observe significant differences (P>0.05).Conclusions: Therefore, to lose weight, blood lipids, and liver enzymes, intend to reduce the risk of cardiovascular disease, probably, performing aerobic exercises along with taking Antom tablets has a greater effect in reducing lipid risk factors for cardiovascular disease. Manuscript profile