Evaluation of Chitosan Films doped with Niosomal Sage Nanoparticles (NIS-Sag NPs) role in food packaging technology

Subject Areas : Journal of Nanoanalysis

mona__saad eldin__elneklawi mona__saad eldin__elneklawi ¹ , Mirhan Darwish ² , Ebtesam Mohamed ³

1 - Biomedical Equipment department, faculty of Applied Medical sciences, October 6 University, Giza, Egypt.
2 - Biophysics Department, Faculty of Science, Cairo University, Giza, Egypt
3 - Biophysics Department, Faculty of Science, Cairo University, Giza, Egypt

Received: 2022-06-04 Accepted : 2024-06-12 Published : 2024-05-31

Keywords: Chitosan, Sage, Food packaging, Nanoparticles, Niosomes.,

Abstract :

Natural extracts have anti-bacterial power that supports their use in food applications. In this work, sage extract was encapsulated into niosomes nanoparticles. Then, chitosan films were doped with different concentrations (100, 200 and 300 μg) of NIS-Sag NPs. The characteristics of pure chitosan film and chitosan doped NIS-Sag NPs films were studied using Raman spectroscopy and UV/VIS spectrophotometer. Scanning electron microscope (SEM) was used to study the surface topography and morphology of the films. In addition, mechanical properties and antibiotic sensitivity test were investigated. The chemical properties of chitosan film doped with NIS-Sag NPs (100-300 μg) was enhanced compared to pure chitosan film which were confirmed by Raman spectroscopy in addition to the UV absorption measurements. SEM results showed that chitosan doped NIS-Sag NPs films has smooth and compacted surface recommended for further application such as food packaging. The doping process was found to enhance the mechanical properties of the films as it improved the tensile strength and elasticity significantly especially for concentration 300 μg. The antibiotic susceptibility test also confirmed this result. These observed improvements of chitosan film doped with 300 μg NIS-Sag NPs are potentially encouraging to adopt the results in food packaging technology.

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