Study the Levels of Total Enzymatic Antioxidants in Patients with Hydatid Cysts

Subject Areas : Journal of Chemical Health Risks

Shaimaa Raheem Hussein ¹ , Hayder Ali Mindeel Neama ²

1 - The Almutafawiqat students` school, The general Directorate of Education, Najaf, Iraq
2 - The Almutafawiqat students` school, The general Directorate of Education, Najaf, Iraq

Received: 2021-07-30 Accepted : 2021-11-27 Published : 2021-10-01

Keywords: Serum, hydatidosis, free radicals, Cystic echinococcosis, ELISA technique, Illiterate,

Abstract :

The current study was done at the Department of Biology, Faculty of Education for Girls, University of Kufa, from May 2019 to April 2020, with the goal of detecting the levels of Total antioxidants in serum of patients before and after hydatid cyst excision. Farmers had the greatest percentages (71.42 %) in the current survey, followed by self-employed people in seven cases (16.67%). This conclusion was supported by additional research. study recorded that the infections was higher among illiterate than literate individuals, and reported that 26 cases (61.90%) were illiterate, 8 cases (19.04%) were primary school, 5 cases (11.90%) were secondary school and 4 cases (9.52%) were of high education which was statistically highly significant (P≤0.05). The results of the concentration of Total antioxidants in serum of patients before hydatid cyst removal using the ELISA technique revealed a significant increase (P 0.05) in the level of Total antioxidants before removing the hydatid cysts, which was 1397.328.35, compared to the level of Total antioxidants after removing the hydatid cysts, which was 1213.413.96, and healthy 1767.913.95. The total antioxidant levels increased significantly (P 0.05) as a function of the ELISA test.

References:

1. Wahlers K., Menezes C.N., Wong M.L., Zeyhle E., 2012. Cystic echinococcosis in sub-Saharan Africa. The Lan. Infect. Dis. 12, 871-880.


2. Ersayit D., Kilic E., Yazar S., Artı T., 2009. Oxidative Stres in Patients with Cystic Echninococcosis: Relationship Between Oxidant and Antioxidant Parameters. Erciyes University. J Health Sci. 18, 159-166.


3. Filippou D., Tselepis D., Filippou G., Papadopoulos V., 2007. Advance in liver echinococcosis: Diagnosis and treatment. Clin. Gastroenterol. Hepatol. 5(2), 152-159


4. Afonso V., Champy R., Mitrovic D., Collin P., Lomri A., 2007. Reactive oxygen species and superoxide dismutases: role in joint diseases. Joint Bone Spine. 74, 324-329.


5. Fattman C.L., Schaefer L.M., Oury T.D., 2003. Extracellular superoxide dismutase in biology and Medicine. Free Radic. Biol Med. 35, 236-256.


6. Lawi Z.K.K., Merza F.A. , Banoon S.R., Al-Saady M.A., Al-Abbood A., 2021. Mechanisms of Antioxidant Actions and their Role in many Human Diseases: A Review. Journal of Chemical Health Risks.11, 45-57.


7. Bertrand K.E., Mathieu N., Inocent G., Honore F.K., 2008. Antioxidant status of bilirubin and uric acid in patients diagnosed with Plasmodium falciparum malaria in Douala. Pak J Biol Sci. 11,1646-1649.


8. Apak R., Gu¨clu¨ K., O¨ zyu¨rek M., Celik S.E., 2008. Mechanism of antioxidant capacity assays and the CUPRAC [cupric ion reducing antioxidant capacity] assay. Microchim Acta. 160(4), 413–419


9. Falih I.Q., Alobeady M.A., Banoon S.R., Saleh M.Y., 2021. Role of Oxidized Low-density Lipoprotein in Human Diseases: A Review. Journal of Chemical Health Risks.11, 71-83.


10. Morgan G.A., Leech N.A., Gloecner G.W., Barrett K.C., 2010. SPSS for introductory statistic: use and interpretation. 2^nd ed. Lawrence Erlbum associates, publisers Mahwah, New Jersey, London.


11. Al-Mukhtar A., Qasim I.K., 2017. Serological Survey of Hydatid Disease in Asymptomatic Peoples in Mosul City, Iraq. Raf J Sci. 26(1), 1-8.


12. Saida L.A., Nouraddin A.S., 2011. Epidemiological study of cystic echinococcosis in Man and slaughtered Animals in Erbil province, Kurdistan Regional-Iraq. Tikrit J Pure Sci. 16(4), 45-50.


13. Mohammed M.O., 2013. The Human Seroprevalence of Echinococcus Granulosus in Sulaimani Governorate. The Iraqi Postgraduate Medical J. 12(1), 45-50.


14. Awatif A.A., 1999. Epidemiology of hydatid disease in Riyadh: a Hospial –based study. Annals Saudi Medicine. 19(5), 450-452


15. Shahrokhabadi R., Rahimi E., Poursahebi R., 2013. Seroepidemiological study of human hydatidosis in Rafsanjan, Kerman. Zahedan J Res Med Sci. 15, 50.16.


16. Yilmaz M., Mert H., Irak K., 2018. The Effect of Fucoidan on the Gentamicin Induced Ne-phrotoxicity in Rats. Fresen Envıron Bull. 27(4), 2235-41.


17. Halliwel B., 1990. How to charecterize a biological antioxidant. Free Radic Res Commun. 1,1-32


18. Irak K., Çelik A.B., Karakoc Z., Çelik Y.Ö., Mert N., Mert K.M., 2018. Oxidant/Antioxidant Status, PON1 and ARES Activities, Trace Element Levels, and Histological Alterations in Sheep with Cystic Echinococcosis Iran. J Paras. 13(3), 448-456.


19. Amanvermez R., 1997. The effectiveness of oxidants [roi, rni] in Echinococcus granulosus hydatid cysts and an investigation of their antioxidant systems. Ph.D.Thesis University of Ondokuz Mayıs, Samsun, Turkey.


20. Halliwell B., 1994. Free radicals antioxidants, human disease: curiosity cause or consequence. Lancet. 344(8924), 721-4.