Comparison of Six Weeks of Weight Training with a Combination of Beta‑hydroxy‑Beta‑methylbutyrate and Creatinine and Two Weeks of Non-training on the Concentrations of some Blood Biochemical Factors in Male Powerlifting Athletes

Subject Areas : Journal of Chemical Health Risks

Mojtaba  Darvishkhadem ¹ (Department of Physical Education and Sports Science, Damghan Branch, Islamic Azad University, Damghan, Iran)
Tahereh  Bagherpour ² (Department of Physical Education and Sports Science, Damghan Branch, Islamic Azad University, Damghan, Iran)
Nematollah  Nemati ³ (Department of Physical Education and Sports Science, Damghan Branch, Islamic Azad University, Damghan, Iran)

Received: 2021-04-22 Accepted : 2021-09-13 Published : 2023-09-01

Keywords: Cholesterol, Triglyceride, Creatinine supplement, Beta-hydroxymethyl Butyrate, High-Density Lipoprotein, Low-Density Lipoprotein,

Abstract :

In this study, concentrations of some blood biochemical factors in male powerlifting athletes were compared through 6 weeks of weight training with combined beta-hydroxy-beta-methylbutyrate (HMB) and creatinine (Cr) supplements and 2 weeks of non-training. Thirty-two male athletes aged 21-30 years were randomly divided into four groups of eight individuals: Cr, HMB, HMB + Cr, and weight training. The training program was designed for 6 weeks and four sessions per week. The HMB group consumed 3 g of the supplement on training days and 1g on non-training days, the Cr group consumed three servings of 5 g on training days and 5 g on non-training days, and the HMB +Cr group consumed the same amount of HMB and Cr supplements as the HMB and Cr groups. During 2 weeks of non-training, the HMB, Cr, and HMB + Cr groups received daily 1 g, 5 g, and 1 g of HMB + 5 g of Cr, respectively. The hypotheses were tested by two-way repeated-measures analysis of variance (ANOVA). Results: There were no significant differences in Cholesterol (Chol.), Triglyceride (TG), and Low-Density Lipoprotein (LDL) levels after the post-test and 2 weeks of non-training. There were significant differences in High-Density Lipoprotein (HDL) in post-test between groups of weight training and HMB (p = 0.000), weight training and HMB + Cr (p = 0.002), Cr and HMB (p = 0.000), and Cr and HMB + Cr (P = 0.001). The weight training and HMB (p = 0.000), weight training and HMB + Cr (p = 0.003), Cr and HMB (p 0.000) =), and Cr and HMB + Cr groups (p = 0.001) were significantly different in 2 weeks of non-training. Conclusion: Six-week weight training with combined HMB and Cr supplement and 2 weeks of non-training can significantly change the concentrations of some blood biochemical factors in male powerlifting athletes.

References:

1.Wilmore J.H., David L.C. Physiology of Exercise and Physical Activity, 1rd ed., Mobtakaran Publications, 1999.

2. Shekarvash B. Lifestyle, Exercise and Health. The Second Congress of Scientific and Sports Schools, 1997.


3. Etemad Z., Ismail Nasab N., 2009. The effect of mid-trunk muscle resistance training on changes in body composition and serum lipids Students of Islamic Azad University, Sanandaj Branch. Scientific Journal of Kurdistan University of Medical Sciences. 14, 20-28.4. Saki H., Gaini A.A., 2013. The effect of short-term use of HMB on CRP and LDH changes due to a session of intense resistance exercise in non-athlete male students. Sports and Biomotor Sciences. 2, 53-61.

5. Campbell T.C., Campbell T.M.  The China Study: The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications for Diet, Weight Loss and Long-term Health. Benbella Books: Texas, USA, 2006.  

6. Alijaniai R. Sport nutrition, 2rd ed., Isfahan: University of Isfahan Publications, 2011. pp. 85-86.

7. Mogharnasi M., Gaini A.A., Goodarzi M., 2003. The relationship between body fat percentage and lean body mass (LBM) with blood fats and lipoproteins (cholesterol, triglyceride, HDL, LDL) in male students Physical Education. Birjand University. 20, 147-157.

8. Rahmani Ghobadi M., Hosseini R., 2014. Relationship between the level of physical activity and cardiovascular risk factors in elderly men. Elderly Journal. 9(4), 316-323.9. Thomson J.S., Watson P.E., Rowlands D.S., 2009. Effects of nine weeks of beta-hydroxy-beta- methylbutyrate supplementation on strength and body composition in resistance trained men. J Strength Cond Res. 23(3), 827-35.

 

10. Nissen S.L., Sharp R.L., 2003. Effect of dietary supplements on lean mass and strength gains with resistance exercise: a meta-analysis. J Appl Physiol. 94(2), 651-9.


11. Bachhawat B.K., Robinson W.G., Coon M.J., 1956. Enzymatic carboxylation of beta-droxyisovaleryl oenzyme. J Biol Chem. 219, 539-50.


12. Balsom P., Söderlund K., Sjödin B., Ekblom B., 1995. Skeletal muscle metabolism during short duration high intensity exercise: Influence of creatinine supplementation. Acta Physiologica Scandinavica. 154(3), 303-10.


13. Fillmore C.M., Bartollin L., Bach R., Park Y., 1999. Nutrition and dietary supplements. Physical Medicine and Rehabilitation Clinics of North America. 10(3), 673-703.


14. Garajian Y., Rahmaninia F., Rahnama N., 2007. Comparison of the effects of creatine supplementation and high protein diet on muscle strength and body composition. Olympic Quarterly. 15(4), 73-83.


15. Johnson S., Knopps D., Miller J., Gorshe J., Luzinski C., 2006. The effects of Creatine monohydrate on 1RM bench press. J Undergrand Kin Res. 1(2), 8-14.


16. Joseph L.J., Davey S.L., Evans W.J., Campbell W.W., 1999. Differential effect of resistance training on the body composition and lipoprotein-lipid profile in older men and women. Metabolism. 48(11), 1474-80.


17. Johnson N.A., Sachinwalla T., Walton D.W., Smith K., Armstrong A., Thompson M.W., George J., 2009 .Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss. Hepatology. 50,1105-12.


18. Fleck S.J., Kraemer W. Designing resistance training programs. 4rd ed., New York: Human Kinetics, 2014.


19. Akbarnejad A., Mousavi Mozaffar M., Kowsari E. Hormones and drugs in sports. Tehran: Narsi Publications, 2013. pp. 128-129.


20. Garajian Y., Arazi H., Dadban Shahamat M., Sayvand Z., 2011. The effect of short-term creatine monohydrate supplementation on performance, strength and muscle work of female student-athletes. Sports Physiology. 47-58.


21. Hemmatfar A., Azadi M., Malek F., 2010. The effect of supplementation of betahydroxy betamethyl butyrate acid (HMB) with resistance training on some biochemical factors of wrestlers' blood. Sports Science Research Quarterly. 1, 60-69.22. Nissen S., Sharp R.L., Panton L., Vukovich M., Trappe S., Fuller J.C., 2000. b-Hydroxy-b-Methylbutyrate (HMB) Supplementation in Humans Is Safe and May Decrease Cardiovascular Risk Factors. Human.Nutrition and Metabolism. 1937-1945.