The Effect of Home Phototherapy in Jaundice and Bilirubin Levels of Neonates in Urmia City

Subject Areas : Journal of Chemical Health Risks

Milad  Ebrahimi Saeid ¹ (Associate Professor of Neonatal-Perinatal Medicine, Department of Pediatric Disease, School of Medicine Shahid Motahari Hospital, Urmia University of Medical Sciences, Urmia, Iran)
Kamran  Dehghan ² (Associate Professor of Neonatal-Perinatal Medicine, Department of Pediatric Disease, School of Medicine Shahid Motahari Hospital, Urmia University of Medical Sciences, Urmia, Iran)
Zahra  Fakoor ³ (Resident of General Surgery, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran)

Received: 2021-08-12 Accepted : 2021-11-08 Published : 2023-06-01

Keywords: Neonates, Home phototherapy, Jaundice, Bilirubin,

Abstract :

Neonatal jaundice is one of the most common diseases in neonatal medicine. Phototherapy is a safe and secure method and is one of the most common treatments of indirect hyperbilirubinemia. This study aimed to evaluate the effect of home phototherapy in neonatal hyperbilirubinemia in Urmia. The present study is a cross-sectional study by the Cohort method. Two hundred three full-term infants older than 24 hours, who were referred to phototherapy for home phototherapy for two months, were selected as the study population. Neonatal serum bilirubin levels in both groups were measured at the beginning and 24 hours after phototherapy. The collected data were analyzed by using SPSS-20. In this study, the mean neonatal bilirubin level before phototherapy was 14.33 ±2.41 mg/dl before and 8.11 ± 2.29 mg/dl after phototherapy. The reduction rate of bilirubin after home phototherapy was 6.6 mg/dl per day and these differences were statistically significant. During phototherapy at home, phototherapy was successful in 96.6% of the neonates recovered, and only seven neonates (3.4%) had complications. Due to the lower prevalence of complications and low duration of treatment, it can be concluded that home phototherapy can be a good alternative for the treatment of neonatal jaundice. Therefore, this method is recommended for the treatment of neonatal jaundice through proper phototherapy training at home.

References:

1.GolshanTafti M., Eftekhari F., Shajari A., 2019. The Effects of Probiotics on Indirect Bilirubin Level in the Infants with Neonatal Jaundice. Alborz University Medical Journal. 8(1), 61-8.

2. Teixeira M.H, Borges V.M.S., Riesgo R.D.S., Sleifer P., 2020. Hyperbilirubinemia impact on newborn hearing: a literature review. Revista da Associação Médica Brasileira. 66(7), 1002-8.


3. Maisels M., 2005. Prevention and management of neonatal hyperbilirubinemia. Avery’s Neonatology Pathophysiology & Management of the newborn 6th ed Philadelphia. 825-33.


4. Muniyappa P., Kelley D., 2020. Hyperbilirubinemia in pediatrics: Evaluation and care. Current Problems in Pediatric and Adolescent Health Care. 50(8), 1038-42.


5. Burke B.L., Robbins J.M., Mac Bird T., Hobbs C.A., Nesmith C., Tilford J.M., 2009. Trends in hospitalizations for neonatal jaundice and kernicterus in the United States, 1988–2005. Pediatrics. 123(2), 524-32.


6. Mesić I., Milas V., Međimurec M., Rimar Ž., 2014. Unconjugated pathological jaundice in newborns. Collegium Antropologicum. 38(1), 173-8.


7. Khatami F., Soltani M., 2007. Home phototherapy; an alternative method for treatment of jaundice in healthy-term newborns. Iranian Journal of Pediatrics. 17(s2), 193-8.


8. Chu L., Qiao J., Xu C., 2020. Home-Based Phototherapy versus Hospital-Based Phototherapy for Treatment of Neonatal Hyperbilirubinemia: A Systematic Review and Meta-Analysis. Clinical Pediatrics. 59(6), 588-95.


9. Keyvanfar S., Sadeghnia A.R., Namnabati M., 2020. The effects of a neonatal critical Care nurse Companionship with Parents during hospital-home transfer of preterm infants on mothers' mood status. Nursing and Midwifery Studies. 9(1), 16-20.


10. Juarez M.C., Grossberg A.L., 2020. Phototherapy in the Pediatric Population. Dermatologic Clinics. 38(1), 91-108.


11. Sardari S., Mohammadizadeh M., Namnabati M., 2019. Efficacy of Home Phototherapy in Neonatal Jaundice. Journal of Comprehensive Pediatrics. 10(1). e82630.


12. Snook J., 2017. Is home phototherapy in the term neonate with physiological jaundice a feasible practice? A systematic literature review. Journal of Neonatal Nursing. 23(1), 28-39.


13. Khatami F., Soltani  M.,  2007. Home  phototherapy;  an  alternative  method  for  treatment  of  jaundice  in  healthy-term newborns. Iranian Journal of Pediatrics. 17(2), 8-193.


14. Zareipour M., Sadaghianifar A., Valizadeh R., Alinejad M., Noorani S., Ghelichi Ghojogh M., 2017. The Effect of Health Promoting Schools Program in Improving the Health Status of Schools in Urmia, North West of Iran. Int J Pediatr. 5(2), 4319-27.


15. Stevenson D.K., 1986. Home phototherapy: risks versus benefits. Clinical Pediatrics. 25(6), 300-2.


16. Zainab K., Adlina S., 2004. Effectiveness of home versus hospital phototherapy for term infants with uncomplicated hyperbilirubinemia: a pilot study in Pahang, Malaysia. Med J Malaysia. 59(3), 395-401.


17. Wu C., Löfqvist C., Smith L.E., VanderVeen D.K., Hellström A., 2012. Importance of early postnatal weight gain for normal retinal angiogenesis in very preterm infants: a multicenter study analyzing weight velocity deviations for the prediction of retinopathy of prematurity. Archives of Ophthalmology. 130(8), 992-9.


18. Blencowe H., Lawn J.E., Vazquez T., Fielder A., Gilbert C., 2013. Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010. Pediatric Research.74(1), 35-49.


19. El-Beshbishi S.N., Shattuck K.E., Mohammad A.A., Petersen JR., 2009. Hyperbilirubinemia and transcutaneous bilirubinometry. Clinical Chemistry. 55(7), 1280-7.


20. Bhutani V.K., Johnson L.H., Schwoebel A., Gennaro S., 2006. A Systems Approach for Neonatal Hyperbilirubinemia in Term and Near‐Term Newborns. Journal of Obstetric, Gynecologic & Neonatal Nursing. 35(4), 444-55.


21. Walls M., Wright A., Fowlie P., Irvine L., Hume R., 2004. Home phototherapy in the United Kingdom. Archives of Disease in Childhood-Fetal and Neonatal Edition. 89(3), F282-F.


22. Atkinson L.R., Escobar G.J., Takayama J.I., Newman T.B., 2003. Phototherapy use in jaundiced newborns in a large managed care organization: do clinicians adhere to the guideline? Pediatrics. 111(5), e555-e61.


23. Golshan Tafti M., Golzari S., 2018. Characterization of Phototherapy at Home in Neonatal with Jaundice. Alborz University Medical Journal. 7(4), 257-65.


24. Chang P.W., Waite W.M., 2020. Evaluation of home phototherapy for neonatal hyperbilirubinemia. The Journal of Pediatrics. 220(3), 80-5.


25. Zareipour M., Sadaghianifar A., Ghelichi Ghojogh M., Ebrahimi H., Asgharzadeh P.,Valizadeh R., 2017. The Relationship between Developmental Growth of Children and Anthropometric Indices in Urmia City, North West of Iran. Int J Pediatr. 5(5), 4975-84.