اثربخشی کاربرد موضعی کارواکرول، آمیتراز و ترکیب کارواکرول آمیتراز در درمان سگ‌های مبتلا به دمودیکوزیس عمومیت یافته

Subject Areas : Parasitology

Sina Fereydooni ¹ , Farnoosh Arfaee ^{2 *} , Mohammad Reza Youssefi ³ , Fatemeh Zahra Gharib ⁴ , Mohaddeseh Abouhosseini-Tabari ⁵

1 - گروه علوم درمانگاهی، دانشکده علوم تخصصی دامپزشکی، واحد علوم و تحقیقات ، دانشگاه آزاد اسلامی، تهران ، ایران
2 - گروه علوم درمانگاهی، دانشکده علوم تخصصی دامپزشکی، واحد علوم و تحقیقات ، دانشگاه آزاد اسلامی، تهران ، ایران
3 - بخش انگل شناسی، دانشکده دامپزشکی، واحد بابل ، دانشگاه آزاد اسلامی، بابل ، ایران
4 - گروه علوم درمانگاهی، دانشکده دامپزشکی، واحد بابل ، دانشگاه آزاد اسلامی، بابل ، ایران
5 - دانشکده دامپزشکی، دانشگاه تخصصی فنآوری های مدرن، آمل ، ایران

Received: 2023-11-22 Accepted : 2023-12-23 Published : 2024-03-03

Keywords: دمودیکوزیس, کارواکرول, آمیتراز, پوست, ریختنی,

Abstract :

دمودیکوزیس سگ یک بیماری پوستی انگلی التهابی است که با افزایش جمعیت گونه‌های جرب دمودکس ایجاد می‌شود. بنابراین، نیاز فوری به درمان موثر، ایمن و در دسترس برای دمودیکوزیس وجود خواهد داشت. این مطالعه با هدف ارزیابی فعالیت کارواکرول 5 درصد، آمیتراز 05/0 درصد و ترکیب کارواکرول- آمیتراز در کشتن جرب های دمودکس کنیس پس از استفاده موضعی و تجزیه و تحلیل بهبود علائم پوستی مرتبط انجام شد. 15 سگ مبتلا به دمودیکوز عمومیت یافته اکتسابی طبیعی به طور تصادفی به 3 گروه مطالعه مساوی تقسیم شدند. سگ ها از پناهگاه حیوانات استان مازندران انتخاب شدند. گروه های درمانی شامل محلول ریختنی 50 میلی لیتر کارواکرول 5 درصد، 50 میلی لیتر آمیتراز 05/0 درصد و مخلوط کارواکرول و آمیتراز 1:1 در غلظت های یکسان بودند. ارزیابی فاکتورهای بالینی شامل شمارش کنه شامل تراشیدن پوست، رشد مجدد مو، جوش های زیرپوستی، قرمزی، میزان کبره بستن و پوسته ریزی در فواصل هفت روزه در چهار هفته بود. تعداد جرب ها در تمام گروه ها به ویژه در کارواکرول 5 درصد به طور معنی داری کاهش یافت (05/0>p). تفاوت معنی داری بین آمیتراز و کارواکرول آمیتراز در روزهای 14، 21 و 28 وجود نداشت (05/0

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