A novel three-component reactions of 4-hydroxycumarine for the synthesis of oxazine derivatives in water

Shams Najafi, Seyyed Jalal; Ghazvini, Maryam; Navabi, Atefeh

doi:10.30495/iranjoc.2023.706237

Manuscript ID : 706237 Visit : 84 Page: 3651 - 3656

10.30495/iranjoc.2023.706237

Article Type: Original Research

A novel three-component reactions of 4-hydroxycumarine for the synthesis of oxazine derivatives in water

Subject Areas : Iranian Journal of Organic Chemistry

Seyyed Jalal Shams Najafi ¹ ()
Maryam Ghazvini ² ()
Atefeh Navabi ³ ()

Received: 2023-09-17 Accepted : 2023-09-17 Published : 2023-08-01

Keywords: 1, Three-component reaction, isocyanide, 2-hydroxyacetophenone, 3-benzoxazine, Isoquinoline,

Abstract :

A simple and proficient method for the synthesis of 1,3-benzoxazine derivatives via three-component reaction of isocyanide and isoquinoline with 2-naphthol in water in the presence of piperidine at 70oC is reported.

References:

Mechanistic Investigation of the [1+4] Cycloaddition Reaction Between Alkyl Isocyanides and 3-benzylidene-2,4-pentanedione: A Theoretical Study
Print Date : 2020-07-17
Synthesis and characterization of PTS and PDATS: Two maiden functionalized energetic polymers having tetrazole and triazine rings
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BF3 catalyzed hydroarylation reactions of arylsubstituted alkynes with different electron rich arenes
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Synthesis of some 3-indolyl heterocycles and evaluation of its antimicrobial activity
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1,3,4-Thiadiazole rings as π-spacers in triphenylamine based dyes: A density functional theory study of reactivity, UV/Visible spectra, structural and optical properties
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Graphical Abstract
Print Date : 2014-05-01

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A novel three-component reactions of 4-hydroxycumarine for the synthesis of oxazine derivatives in water