Catalyst free synthesis of pyrrole derivatives using multicomponent reactions

Sharifi, Samanehsadat; Haeizadeh, Narjes

doi:10.30495/iranjoc.2023.704940

Manuscript ID : 704940 Visit : 144 Page: 3595 - 3599

10.30495/iranjoc.2023.704940

Article Type: Original Research

Catalyst free synthesis of pyrrole derivatives using multicomponent reactions

Subject Areas : Iranian Journal of Organic Chemistry

Samanehsadat Sharifi ¹ , Narjes Haeizadeh ²

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Received: 2023-08-14 Accepted : 2023-08-14 Published : 2023-05-01

Keywords: Three-component reaction, Primary Amines, Pyrrole, green chemistry, N-formylmorpholine,

Abstract :

A convenient and efficient procedure for the synthesis of substituted pyrroles has been reported based on three component reactions of primary amines and activated acetylenic compounds in the presence of N-formylmorpholine as a green solvent. The above synthetic procedure offers rapid access to novel and diversely substituted pyrrole derivatives.

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Mechanistic Investigation of the [1+4] Cycloaddition Reaction Between Alkyl Isocyanides and 3-benzylidene-2,4-pentanedione: A Theoretical Study
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Synthesis and characterization of PTS and PDATS: Two maiden functionalized energetic polymers having tetrazole and triazine rings
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BF3 catalyzed hydroarylation reactions of arylsubstituted alkynes with different electron rich arenes
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Synthesis of some 3-indolyl heterocycles and evaluation of its antimicrobial activity
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1,3,4-Thiadiazole rings as π-spacers in triphenylamine based dyes: A density functional theory study of reactivity, UV/Visible spectra, structural and optical properties
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Graphical Abstract
Print Date : 2014-05-01

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Catalyst free synthesis of pyrrole derivatives using multicomponent reactions